With the advent of revolutionary technologies such as artificial intelligence, machine learning, cloud computing, big data, and IoT; Secure Knowledge Management (SKM) continues to be an important research area that deals with methodologies for systematically gathering, organizing, and disseminating information in a secure manner. The recent development of Artificial Intelligence (AI) in the security arena shows a promising future, and there is no doubt that AI can provide new ideas and tools for SKM. Therefore, this conference on SKM will bring together researchers & practitioners from academia, industry, and government on a global scale. The scope and focus of SKM-2021 conference are to present and discuss the most recent innovations, trends, and concerns including practical challenges encountered and solution adopted with special emphasis on AI.