BITS Pilani

  • Page last updated on Wednesday, March 25, 2015


Research & Development
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Sponsored Projects

Research at the department of biological sciences is multidisciplinary.
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Vijayashree Nayak's Lab

Research focus is to study molecular cell signalling mechanisms involved in chronic infections associated carcinogenesis with cell cycle regulation loss and epithelial mesenchymal transition (EMT). Our interest also lies in developing novel scaffolds for tissue engineering applications, Nano technology in drug delivery and screening drugs for anticancer activity.  
Selected Publications:
  • Priyanka Dwivedi, Sumrita Bhat, Vijayashree Nayak, Ashok Kumar. Study of Different Delivery Modes of Chondroitin Sulfate Using Microspheres and Cryogel Scaffold for Application in Cartilage Tissue Engineering, International Journal of Polymeric Materials. Nov 2014, Vol. 63: 859-872.
  • Yogesh D. Walwalkar, Rajni Gaind and Vijayashree Nayak. Study on Salmonella typhi occurrence in gall bladder of patients suffering from chronic cholelithiasis - a predisposing factor for carcinoma of gall bladder; Diagnostic Microbiology and Infectious Disease;2013,  77, 1, 69–73.
  • Archana Sharma, Sumrita Bhat, Tanusree Vishnoi, Vijayashree Nayak and Ashok Kumar. Three dimensional supermacroporous carrageenaan-gelatin cryogel matrix for tissue engineering applications; Biomed Research International, 2013, Article ID 478279.
  • Ganesh Chandra Jagetia and Vijayashree Nayak. Activity by Accelerating Chromosome Damage in HeLa Cells Exposed to Diff erent Doses of γ-Radiation, Medicinal and Aromatic Plant Science and Biotechnology ©2012 Global Science Books , June, 2012.
  • L. Nirmala, Vijayashree Nayak, Deecaraman. Immunoevaluation of Typhoid antigen by using potato starch natural biodegradable polymer as a single contact used as an adjuvant, Research Article, International Journal of Pharmacy and Pharmaceutical Sciences, ISSN- 0975-1491, vol 3, issue 4.2011.
List of Projects:
  • A novel Biodegradable scaffold for cartilage tissue engineering
  • To study the correlation between S. typhi infection and gall bladder cancer
  • Study on EMT regulation through TGFβ/SMADs in gall bladder disease
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Annotate Biomolecules Computationally

Understanding of complex biological processes by integrating data from many inter-related yet heterogeneous resources, which help to improve drug discovery.
We explore in protein interaction biology :
  • Functional classification
  • Sequence-structure-function relationship
  • Molecular-mechanisms
  • Protein mobility, flexibility and specificity  implication
Contact: Sukanta Mondal, Ph.D.

Selected Publications:
  • Dhole K, Singh G, Pai PP, Mondal S*. (2014) Sequence-based prediction of protein-protein interaction sites with L1-logreg classifier. J Theor Biol. 348:47-54.
    [Featured on Global Medical Discovery as a Key Scientific Article contributing to excellence in biomedical research.]
  • Mondal S, Nagao C, Mizuguchi K. (2010) Detecting subtle functional differences in ketopantoate reductase and related enzymes using a rule-based approach with sequence-structure homology recognition scores. Protein Eng Des Sel.23:859-869.
  • Mondal S, Babu RM, Bhavna R, Ramakumar S.  (2007) In silico detection of binding mode of J-superfamily conotoxin pl14a with Kv1.6 channel.  In Silico Biol.7:175-186.

Research collaborations


Ghent University, Ghent, Belgium
Laboratoire de Biotechnologie de l’Environnement, INRA, Narbonne, France
Helmholtz Centre for Environmental Research, Leipzig, Germany
Technical University Hamburg Harburg, Germany
Institute of Agricultural and Urban Ecological Projects, Berlin, Germany
Department of Endocrinology, Diabetes and Rheumatology, Düsseldorf, Germany
Department of Biotechnology, University of Pune, India
National Centre for Cell Science, Pune, India
Indian Institute of Science, Bangalore, India
Bose Institute, Kolkata, India
Department of Physiology, University of Calcutta, India
Indian Institute of Technology, Kharagpur, India
CAS in Crystallography and Biophysics, University of Madras, India
Department of Zoology, Banaras Hindu University, Varanasi, India
Safdurjung Hospital, ICMR, New Delhi, India
Goa Medical College, Goa, India
Department of Anatomy, National University of Singapore, Singapore
Rutgers University, New Brusnwick, USA
University at Buffalo, The State University of New York, USA
Department of Health Sciences, University of Delaware, USA
Cancer Nanotechnology Platform, University of Missouri, USA
Cell Science and Proteomics, GE healthcare Life Sciences, Bangalore, India
German Technical Cooperation (GIZ), New Delhi, India
Hitachi India Pvt. Ltd, India
Oil Natural Gas corporation limited, India

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