Current Activities

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Areas of Research

  • Biochemistry and Enzyme Biotechnology
  • Bio-Informatics and Computational Biology
  • Cancer Biology and Chronic Diseases
  • Environmental and Microbial Biotechnology
  • Parasitology and Vector Biology
  • Plant Biotechnology

  • Biochemistry and Enzyme Biotechnology

    Dr. Pankaj Sharma:
    • Phytochemical characterization of desert plants with respect to the presence of medicinally important compounds
    • Purification and biochemical characterization of enzymes participating in metabolism of flavonoids and other secondary metabolites in legumes

    Dr. Santosh K Padhi:
    • Engineering enzymes using advanced protein engineering techniques towards the synthesis of pharmaceutical intermediates, optically pure compounds, and fine chemicals
    • Developing new engineered enzymes and exploring their novel biocatalytic properties
    • Exploring new enzymes and enzymatic sources for novel biotransformations
    • Exploring new enzymatic routes for the synthesis of chiral compounds, fine chemicals and pharmaceutical intermediates

  • Bio-Informatics and Computational Biology

    Prof. Shibasish Chowdhury:
    • Understanding structure-function relationship of Protein and DNA
    • Understanding protein evolution process

  • Cancer Biology and Chronic Diseases

    Dr. Uma S Dubey:
    • Evaluating anti-cancer properties of camel milk and studying its mechanism of action
    • Experimental approaches to validate mathematical models on cancer and immune cell interaction kinetics in presence or absence of potent anti-cancer drugs  and immunopotentiating agents

    Dr. Praphulla C Shukla:
    • To understand the non-coding genome in the settings of myocardial infarction and atherosclerosis. The experimental systems that we use are vascular smooth muscles and endothelial cells along with in-vivo mouse myocardial infarction models

    Dr. Rajdeep Chowdhury:
    • Characterizing molecular mechansims involved in cancer chemo-resistance
    • Role of autophagy and associated signaling in cancer chemo-resistance in hepatocellular carcinoma
    • Role of non-coding RNAs in cancer chemo-resistance in hepatocellular carcinoma

    Dr. Sudeshna Mukherjee:
    • Role of pro-inflammatory cytokines in cancer progression, especially in epithelial to mesenchymal transition (EMT)

  • Environmental and Microbial Biotechnology

    Prof. S.K. Verma:

    • Development of recombinant DNA based biosensor device for detection of arsenic in water samples
    • Characterization and pharmacological evaluation of bioactive compounds
    • Development of bioleaching technology for recovery of metal from ores and biosorption technology for removal of radio nuclide from nuclear industry waste
    • Biodegradation of organic pollutants
    • Bio-Diesel production from microalgae

    Prof. Jitendra Panwar:
    • Development of novel biomimetic approach towards synthesis of metal and metal oxide nanoparticles and their characterization
    • Mechanistic studies behind biosynthesis of nanoparticle emphasizing protein-nanoparticle interactions

    Dr. Prabhat N. Jha:
    • Screening and optimization of plant growth promoting endophytic bacteria for their potential as biofertilizer candidate
    • To investigate molecular mechanism for endophytic colonization in crop plants such as wheat and pearl millet
    • Study of immune response of host plants to beneficial bacteria
    • Isolation and characterization of plant associated bacteria which can ameliorate abiotic stress in host plants through induced systemic tolerance
    • Study of expression and regulation of ACC deaminase in associative bacteria
    • Endophytic bacteria assisted phytoremediation of organic contaminants
    • Developing new enzyme assays

  • Parasitology and Vector Biology

    Prof. A.K. Das:
    • Understanding complicated malaria (Plasmodium falciparum & Plasmodium vivax), using patient derived samples
    • Possible bio markers, for severe malaria
    • Creating and using Systems networks for identifying important molecules
    • Investigation of identified molecules
    • New diagnostic approaches and concepts, focused on, but not restricted to malaria
    • Understanding molecules involved in immune perturbation in malaria and comparison with immune perturbation in other human diseases
    • Using novel plasmid sequences from isolated Lactobacilli, for different purposes

    Prof. Sanjeev Kumar:
    • Importance of reactive oxygen species (ROS) in innate immunity
    • Role of peroxidases in immunity against Plasmodium and bacteria
    • Role of mosquito metabolic and oxidative pathways in regulation of Plasmodium development
    • Screening of natural photochemical as anti-mosquito agent

    Prof. Lalita Gupta:
    • Analysis of mosquito immune signaling pathways in Anopheles culicifacies mosquitoes  
    • Surveillance and mapping of vector populations and prediction of vector borne disease transmission in Rajasthan region
    • Arresting Plasmodium development inside the mosquito gut by utilizing mosquito immune genes and micro biota  
    • Role of lipoproteins in Aedes aegypti development and diseases transmission

    Dr. Vishal Saxena:
    • Characterization of vaccine candidate antigens of the malarial parasites of Plasmodium falciparum and Plasmodium vivax
    • Characterization of apicoplast targeted nuclear encoded proteins in Plasmodium vivax Indian isolates
    • Characterization of the apicoplast genome from Plasmodium vivax
    • Characterization of nuclear encoded protein particiapting in the apicoplast division
    • Characterization of Isoprenoid biosynthetic pathway genes in apicoplast of Plasmodium vivax
    • Modeling of hypothetical proteins using bioinformatic tools to identify novel drug targets in malaria parasite

    Dr. Shilpi Garg:
    • Studies on drug resistance marker genes in Plasmodium falciparum and Plasmodium vivax
    • Analysis of metabolic pathway genes in Plasmodium falciparum and Plasmodium vivax
    • Characterization of Fe-S cluster pathway in apicoplast of Plasmodium vivax
    • Analysis of hypothetical/ putative proteins dual targeted to apicoplast and mitochondria in Plasmodium vivax

  • Plant Biotechnology

    Dr. Rajesh Mehrotra:
    • Understanding the circuitary of gene regulation of abiotic and biotic stress inducible gene focussing on cis regulatory modules
    • Understanding the patterns and landscape of cis regulatory modules across different plant species with special emphasis on evolutionary significance of ACGT repeat element
    • Designing inducible promoters for dehydration tolerance
    Dr. Sandhya Mehrotra:
    • Tracing evolutionary history of carbon concentration mechanisms across all autotrophic organisms
    • Introducing carbon concentration mechanisms into C3 plants to increase their productivity
    • Designing abiotic stress responsive designer promoter for plants
    Dr. B Vani:
    • Nitrate assimilatory mechanism in Spirulina platensis

MOU Signed with National Institute of Health, USA

BITS, Pilani has signed a MOU with National Institute of Health, USA for research collaboration in the area of epigenetics and human health. The collaboration is aimed at students and faculty exchange programme for completing doctoral thesis work.

An institution deemed to be a University estd. vide Sec.3 of the UGC Act,1956 under notification # F.12-23/63.U-2 of Jun 18,1964

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