Prof. Kavi Devraj

Associate Professor
Department of Biological Sciences

Neuroscience and Biomedical Engineering - Blood-Brain Barrier (BBB), Infections, AD, Neurovascular Unit (NVU), Transport Mechanisms and Kinetics, CNS Diseases (Stroke, Cancers), BBB Targeted Therapeutics, CNS Drug Delivery, Microfluidic Devices
Birla Institute of Technology & Science, Pilani
Hyderabad Campus
Jawahar Nagar, Kapra Mandal
Dist.-Medchal-500 078
Telangana, India

Sponsored Projects  

Targeting neurovascular unit (NVU) for therapeutic modulation of blood-brain barrier (BBB) function in CNS diseases” DBT Ramalingaswamy Fellowship,  BITS-Pilani, Hyderabad Campus, India (80 Lakhs) (2023-2027)
Establishment of a blood-brain barrier model (BBB) for studying the invasion of Toxoplasma gondi into the brain across BBB in cerebral toxoplasmosis” in collaboration with Prof. Dr. Nishith Gupta, BITS-Pilani, Hyderabad Campus, India (10 Lakhs)  (2023-2024)
Effect of Wnt signalling on transcellular transport in an in vitro model of the blood-brain barrier (BBB) ” funded by Goethe University Clinic, Germany (8.5 Lakhs) (2010-2012)
Role of muscarinic receptors at the blood-brain barrier in amyloid beta transport” funded by AC Immune Inc., Switzerland (26.5 Lakhs) (2012-2014)
Role of the VE-PTP inhibitor AKB 9785 in the rescue of VEGF mediated brain endothelial permeability”  funded by Aerpio Pharmaceuticals Inc., USA (35 Lakhs) (2015-2018)
Transmigration of meningeal pathogens into the brain across the blood-brain barrier and its therapeutic targeting in preclinical disease models” in collaboration with Prof. Dr. Volkhard Kempf, funded by German Research Foundation, Germany (90 Lakhs) (2015-2020)
Dual role of S1P signalling at the BBB: early tightening & late disruptive effects” funded by Leducq Foundation Sphingonet Consortium, USA (18 Lakhs) (2017-2019)
Development of FACS-based method for isolation and analysis of NVU cells, and its application to neurological diseases with BBB dysfunction” funded by Edinger Foundation, Germany (65 Lakhs) (2019-2022)