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Dr. Akash Chaurasiya 

Assistant Professor
Department of Pharmacy

Oral Bioavailability enhancement using novel approaches, Cancer therapeutics, Liposomes, Lipid Emulsion, Development of nano-particulate/vesicular carrier system for enhancing drug efficacy and safety, Advanced lyophilization technique, Differentiated product development (505b2 based approaches)
Birla Institute of Technology & Science, Pilani
Hyderabad Campus
Jawahar Nagar, Kapra Mandal
Dist.-Medchal-500 078
Telangana, India

Book Chapters

  1. Keerti Mishra, Sonia Verma, Pooja Yadav, Amrendra K. Tiwari, J.V.U.S. Chakradhar, Pavan K. Yadav, Akash Chaurasiya, Manish K. Chourasia, Chapter 20 - Methods for preparation of giant liposomes: Conventional methods; modified electro-techniques, In:Liposomes in Drug Delivery, Academic Press, 2024, Pages 517-538, ISBN 9780443154911, https://doi.org/10.1016/B978-0-443-15491-1.00002-X.
  2. Akash Chaurasiya, Sonali Singh, Kanan Panchal, Rishi Paliwal, Akanksha Malaiya, Chapter 12 - Fundamentals of a targeted drug delivery system, In:Molecular Pharmaceutics and Nano Drug Delivery, Academic Press, 2024, Pages 289-309, ISBN 9780323919241, https://doi.org/10.1016/B978-0-323-91924-1.00007-1.
  3. Akash Chaurasiya, Amruta Gorajiya, Jayabalan Nirmal, Chapter 19 - Stability testing parameters of nanoscaled product development, In: Micro and Nano Technologies, Multifunctional Nanocarriers, Elsevier, 2022, Pages 475-500, ISBN 9780323850414, https://doi.org/10.1016/B978-0-323-85041-4.00010-X.
  4. Rishi Paliwal, Akash Chaurasiya, Kanan Panchal, Puja Nayak, Nilosha Parveen, Shivani Rai Paliwal, Chapter 3 - Engineering and functionalization of nanomaterials for theranostic applications in infectious diseases, In: Developments in Microbiology, Nanotheranostics for Treatment and Diagnosis of Infectious Diseases, Academic Press, 2022, Pages 45-71, ISBN 9780323912013, https://doi.org/10.1016/B978-0-323-91201-3.00003-7.
  5. Akash Chaurasiya, Sumeet Katke, Kanan Panchal, Jayabalan Nirmal, Chapter 9 - Biologics for the management of dementia, In: Nanomedicine-Based Approaches for the Treatment of Dementia, Academic Press, 2023, Pages 193-234, ISBN 9780128243312, https://doi.org/10.1016/B978-0-12-824331-2.00001-7.
  6. Akash Chaurasiya, Parameswar Patra, Pranathi Thathireddy, Amruta Gorajiya. Chapter 6 - PLGA-based Micro- and Nano-particles: From Lab to Market. In: Micro- and Nanotechnologies-Based Product Development, CRC-Taylor & Francis, 2021, Pages 83-95. https://doi.org/10.1201/9781003043164
  7. Ridahunlang Nongkhlaw, Parameswar Patra, Akash Chaurasiya, Nirmal Jayabalan, Sachin Dubey, Chapter 6 - Biologics: Delivery options and formulation strategies, Drug Delivery Aspects, Elsevier, 2020, Pages 115-155, ISBN 9780128212226, https://doi.org/10.1016/B978-0-12-821222-6.00006-3.
  8. Akash Chaurasiya, Sumeet Katke & Kanan Panchal, “Nanotechnology-based approaches for Cancer Therapeutics”. In Nanomedicine, Nanotheranostics and Nanobiotechnology: Fundamentals and Applications, CRC-Taylor and Francis (In press), 2024. https://www.taylorfrancis.com/books/mono/10.1201/9781003130055/nanomedicine-nanotheranostics-nanobiotechnology-rishi-paliwal-shivani-rai-paliwal
  9. Farhan Jalees Ahmad & Akash Chaurasiya, ‘Pharmaceutical Utility’, Leon Lachman & Herbert A Lieberman–Theory and Practice of industrial Pharmacy, IV Edition, 2013, CBS Publishers and Distributors, Pvt Ltd., New Delhi.

Publications

After joining BITS Pilani (TPRL)

  1. Patra, P., Katke, S., Singh, S., Panchal, K., Johari, A., Pawar, A., Paliwal, R., & Chaurasiya, A. (2024). Development and Evaluation of Stable Long Circulating Decitabine-loaded Copolymeric Nanoparticles: Harnessing QbD Approach and Lyophilization Technique. Journal of Pharmaceutical Innovation. https://doi.org/10.1007/s12247-024-09836-8
  2. Shinde, A., Panchal, K., Patra, P., Singh, S., Enakolla, S., Paliwal, R., & Chaurasiya, A. (2024). QbD Enabled Development and Evaluation of Pazopanib Loaded Nanoliposomes for PDAC Treatment. AAPS PharmSciTech25(5), 97. https://doi.org/10.1208/s12249-024-02806-w
  3. Panchal, K., Reddy, A., Paliwal, R., & Chaurasiya, A. (2024). Dynamic intervention to enhance the stability of PEGylated Ibrutinib loaded lipidic nano-vesicular systems: transitioning from colloidal dispersion to lyophilized product. Drug delivery and translational research, 10.1007/s13346-024-01555-4. Advanced online publication. https://doi.org/10.1007/s13346-024-01555-4
  4. Nessa, S., Lavanya, S., Routray, R. K., Chaurasiya, A., Kulkarni, O. P., & Begum, A. S. (2024). Anti-rheumatoid arthritis potential of Halodule pinifolia: development, characterization and in vivo evaluation of H. pinifolia-based oral suspension and lipid nano-emulsion. Inflammopharmacology32(2), 1203–1223. https://doi.org/10.1007/s10787-024-01431-0
  5. Rani, S., Sahoo, R. K., Mahale, A., Panchal, K., Chaurasiya, A., Kulkarni, O., Kuche, K., Jain, S., Nakhate, K. T., Ajazuddin, & Gupta, U. (2023). Sialic Acid Engineered Prodrug Nanoparticles for Codelivery of Bortezomib and Selenium in Tumor Bearing Mice. Bioconjugate chemistry34(9), 1528–1552. https://doi.org/10.1021/acs.bioconjchem.3c00210
  6. Pardhi, E., Yadav, R., Chaurasiya, A., Madan, J., Guru, S. K., Singh, S. B., & Mehra, N. K. (2023). Multifunctional targetable liposomal drug delivery system in the management of leukemia: Potential, opportunities, and emerging strategies. Life sciences325, 121771. https://doi.org/10.1016/j.lfs.2023.121771
  7. Gupta, T., Sahoo, R. K., Singh, H., Katke, S., Chaurasiya, A., & Gupta, U. (2023). Lipid-Based Nanocarriers in the Treatment of Glioblastoma Multiforme (GBM): Challenges and Opportunities. AAPS PharmSciTech24(4), 102. https://doi.org/10.1208/s12249-023-02555-2
  8. Kumar, R. M., Kumar, H., Bhatt, T., Jain, R., Panchal, K., Chaurasiya, A., & Jain, V. (2023). Fisetin in Cancer: Attributes, Developmental Aspects, and Nanotherapeutics. Pharmaceuticals (Basel, Switzerland)16(2), 196. https://doi.org/10.3390/ph16020196
  9. Rani, S., Sahoo, R. K., Kumar, V., Chaurasiya, A., Kulkarni, O., Mahale, A., Katke, S., Kuche, K., Yadav, V., Jain, S., Nakhate, K. T., Ajazuddin, & Gupta, U. (2023). N-2-Hydroxypropylmethacrylamide-Polycaprolactone Polymeric Micelles in Co-delivery of Proteasome Inhibitor and Polyphenol: Exploration of Synergism or Antagonism. Molecular pharmaceutics20(1), 524–544. https://doi.org/10.1021/acs.molpharmaceut.2c00752
  10. Panchal, K., Katke, S., Dash, S. K., Gaur, A., Shinde, A., Saha, N., Mehra, N. K., & Chaurasiya, A. (2023). An expanding horizon of complex injectable products: development and regulatory considerations. Drug delivery and translational research13(2), 433–472. https://doi.org/10.1007/s13346-022-01223-5
  11. Priya, S., Batra, U., R N, S., Sharma, S., Chaurasiya, A., & Singhvi, G. (2022). Polysaccharide-based nanofibers for pharmaceutical and biomedical applications: A review. International journal of biological macromolecules218, 209–224. https://doi.org/10.1016/j.ijbiomac.2022.07.118
  12. Panchal, K., Sahoo, R. K., Gupta, U., & Chaurasiya, A. (2021). Role of targeted immunotherapy for pancreatic ductal adenocarcinoma (PDAC) treatment: An overview. International immunopharmacology95, 107508. https://doi.org/10.1016/j.intimp.2021.107508
  13. Chaurasiya, A., Gorajiya, A., Panchal, K., Katke, S., & Singh, A. K. (2022). A review on multivesicular liposomes for pharmaceutical applications: preparation, characterization, and translational challenges. Drug delivery and translational research12(7), 1569–1587. https://doi.org/10.1007/s13346-021-01060-y
  14. Shinde, A., Panchal, K., Katke, S., Paliwal, R., & Chaurasiya, A. (2022). Tyrosine kinase inhibitors as next generation oncological therapeutics: Current strategies, limitations and future perspectives. Therapie77(4), 425–443. https://doi.org/10.1016/j.therap.2021.10.010
  15. Paliwal, R., Kumar, P., Chaurasiya, A., Kenwat, R., Katke, S., & Paliwal, S. R. (2022). Development of Nanomedicines and Nano-Similars: Recent Advances in Regulatory Landscape. Current pharmaceutical design28(2), 165–177. https://doi.org/10.2174/1381612827666211115170001
  16. Chaurasiya, A, Patra, P, Singh, S & Chourasiya, M. (2020). Potential of nanotechnology based approaches for HIV/AIDS treatment, ISSRF Newletter, Indian Society for the Study of Reproduction and Fertility, 26, 63-66.

Before joining BITS Pilani

  1. Singh, A. K., Chaurasiya, A., Warsi, M. H., Chourasiya, M., Jain, G. K., Asati, D., Khar, R.K. & Mukherjee, R. (2012) Oral pharmacokinetic study of exemestane SMEDDS and suspension in rat plasma by Liquid Chromatography-Mass Spectrometric analysis, Journal of Liquid Chromatography & Related Technologies, 35, 2162-2174.
  2. Chaurasiya, A., Singh, A. K., Upadhyay, S. C., Asati, A., Ahmad, F. J., Mukherjee, R., & Khar,  K. (2012) Lipidic nanocarrier for oral bioavailability enhancement of an anticancer agent: Formulation design & evaluation, Advance Science Letter, 11, 43-52.
  3. Maheshwari, C., Pandey, R. S., Chaurasiya, A., Kumar, A., Selvam, D. T., Prasad, G. B., & Dixit, V. K. (2011). Non-ionic surfactant vesicles mediated transcutaneous immunization against hepatitis B. International immunopharmacology, 11(10), 1516–1522.
  4. Warsi, M.H., Chaurasiya, A., Jain, G. K., Pathan, S., Chander, P., Singh, A. K., Talegaonkar, S., Ahmad, F. J., & Khar, R. K. (2011) Aqueous Humor Pharmacokinetics of Dorzolamide Loaded PLGAChitosan Nanoparticles by Ultra Performance Liquid Chromatography, Current Pharmaceutical Analysis,, 7, 189-194.
  5. Singh, A. K., Chaurasiya, A., Awasthi, A., Mishra, G., Asati, D., Khar, R. K., & Mukherjee, R. (2009). Oral bioavailability enhancement of exemestane from self-microemulsifying drug delivery system (SMEDDS). AAPS PharmSciTech10(3), 906–916.
  6. Singh, A. K., Chaurasiya, A., Jain, G. K., Awasthi, A., Asati, D., Mishra, G., Khar, R. K., & Mukherjee, R. (2009). High performance liquid chromatography method for the pharmacokinetic study of bicalutamide SMEDDS and suspension formulations after oral administration to rats. Talanta78(4-5), 1310–1314.
  7. Jain, S. K., Chaurasiya, A., Gupta, Y., Jain, A., Dagur, P., Joshi, B., & Katoch, V. M. (2008). Development and characterization of 5-FU bearing ferritin appended solid lipid nanoparticles for tumour targeting. Journal of microencapsulation25(5), 289–297.
  8. Singh, A. K., Chaurasiya, A., Singh, M., Upadhyay, S. C., Mukherjee, R., & Khar, R. K. (2008). Exemestane loaded self-microemulsifying drug delivery system (SMEDDS): development and optimization. AAPS PharmSciTech9(2), 628–634. https://doi.org/10.1208/s12249-008-9080-6