Development of nano-particulate based carrier system for anticancer therapeutics delivery, Development of vesicular carrier system for enhancing drug efficacy and safety, Oral Bioavailability enhancement using novel approaches, Lyophilization Technique, Differentiated Product Development (505b2 based approaches), Cancer therapeutics, 505b2, Liposomes, Lipid Emulsion, LIpid Crystal, Formulation Development, Nanoparticles
Birla Institute of Technology & Science, Pilani Hyderabad Campus Jawahar Nagar, Kapra Mandal Dist.-Medchal-500 078 Telangana, India
23rd Biotechnology Ignition Grant (BIG), BIRAC setup by DBT awarded to Dr. Akash Chaurasiya and Kanan Panchal (Budget: Rs.49.96 Lakhs).
Article accepted in Drug Delivery and Translational Research (Impact Factor: 5.4) entitled "Dynamic intervention to enhance the stability of PEGylated Ibrutinib loaded lipidic nano-vesicular systems: transitioning from colloidal dispersion to lyophilized product" by Ms. Kanan Panchal (Ph.D. student)
Published book chapter on “ Fundamentals of targeted drug delivery system” published in Molecular pharmaceutics and nano drug delivery: Fundamentals and Challenges, Elsevier. pp 289- 309. co-contributed by Ms. Sonali Singh (Ph.D. student) and Ms. Kanan Panchal (Ph.D.student).https://doi.org/10.1016/B978-0-323-91924-1.00007-1
Patent listed in Orange Book entitled "Stable liquid formulations of cyclophosphamide and processes to prepare the same", Patent No. 11,382,923 B2, Jul . 12 , 2022, Riyaz Ahmed Shaik, Ananya Saha, Syb Janardhan Garikipati, Akash Chaurasiya, Bhavesh Vallabhbhai Patel, Harshal Bhagwatwar, Sumitra Ashok Pillai
An Industry funded research project sanctioned entitled " Development, optimization and characterization of anticancer drug loaded stable liposomal formulation" to Dr. Akash Chaurasiya (Budget: Rs.22 Lakhs).
An Industry funded research project sanctioned entitled "Development, optimization and evaluation of stable multidose injectable formulation of anticancer drug" to Dr. Akash Chaurasiya (Budget: Rs.21.44 Lakhs).
Article accepted in Bioconjugate Chemistry Manuscript (Impact Factor: 6.06) entitled "Sialic Acid Engineered Prodrug Nanoparticles for Co-delivery of Bortezomib and Selenium in Tumor Bearing Mice"
Article published in Life Science (Impact Factor: 6.78) entitled "Multifunctional targetable liposomal drug delivery system in the management of leukemia: Potential, opportunities, and emerging strategies"
Article published in AAPS PharmSciTech (Impact Factor: 4.026) entitled "Lipid Based Nanocarriers in the Treatment of Glioblastoma Multiforme (GBM): Challenges and Opportunities", co-authored by Mr. Sumeet Katke (Ph.D. student).
Article published in Molecular Pharmaceutics (Impact Factor: 5.364) entitled “HPMA-PCL polymeric micelles in co-delivery of proteasome inhibitor and polyphenol: Exploration of synergism or antagonism”, co-authored by Mr. Sumeet Katke (Ph.D. student).
Ms. Kanan Panchal (Ph.D. student) was awarded with 'Best E-poster Presentation' at National Seminar on "Pharmaceutical Product Development: A Context of Indian Pharmaceutical Industry and Research" organized by the Department of Pharmacy, Indira Gandhi National Tribal University, Amarkantak, Madhya Pradesh, India held on April 12, 2022.
Book chapter on “Stability Testing Parameters of Nano scaled Product Development” published in Multifunctional Nanocarriers, Elsevier, pp 475-500, 2022.
Article published in Drug Delivery and Translational Research (Scopus indexed; Impact Factor: 5.671) entitled “An expanding horizon of complex injectable products: Development and regulatory considerations”, co-authored by Ms. Kanan Panchal (Ph.D. student) & Mr. Sumeet Katke (Ph.D. student). https://doi.org/10.1007/s13346-022-01223-5
Article published in International Journal of Biological Macromolecules (Scopus indexed; Impact Factor: 8.025) entitled “Polysaccharide-based nanofibers for pharmaceutical and biomedical applications: A review”. https://doi.org/10.1016/j.ijbiomac.2022.07.118
Book chapter on “Engineering and functionalization of nanomaterials for theranostic applications in infectious diseases” published in Nanotheranostics for Treatment and Diagnosis of Infectious Diseases, Elsevier, pp 45-71, 2022, co-contributed by Ms. Kanan Panchal (Ph.D. student). https://doi.org/10.1016/B978-0-323-91201-3.00003-7
Patent application is filed by Dr. Akash Chaurasiya for 'Lipid Based pharmaceutical composition of BTK inhibitor', co-invented by Ms. Kanan Panchal (Ph.D. student).
Patent application is filed by Dr. Akash Chaurasiya for 'Stable oral compositions of posaconazole for treating fungal infections', co-invented by Ms. Kanan Panchal (Ph.D. student) and Mr. Sumeet Katke (Ph.D. student).
Novartis Healthcare has sanctioned a consultancy project on Long-Acting Injectables (LAI) to Dr. Akash Chaurasiya (Budget: Rs.5.25 Lakhs). Ms. Nikita Raheja (M. Pharm. student) & Ms. Srusthi Mhatre (M. Pharm. student) are appointed as a research intern for this project.
Article published in Therapies (Scopus indexed; Impact Factor: 3.367) entitled “Tyrosine kinase inhibitors as next generation oncological therapeutics: Current strategies, limitations and future perspective”, co-authored by Ms. Aishwarya Shinde (M.Pharm student), Ms. Kanan Panchal (Ph.D. student) & Mr. Sumeet Katke (Ph.D. student). https://doi.org/10.1016/j.therap.2021.10.010
Article published in Current Pharmaceutical Design (Scopus indexed; Impact Factor: 3.310) entitled “Development of nanomedicines and nanosimilars: Recent advances in regulatory landscape”, co-authored by Mr. Sumeet Katke (Ph.D. student). https://doi.org/10.2174/1381612827666211115170001
Article published in Drug Delivery and Translational Research (Scopus indexed; Impact Factor: 5.671) entitled “A review on multivesicular liposomes for pharmaceutical aplications: Preparation, characterization and translational challenges”, co-authored by Mr. Sumeet Katke (Ph.D. student) & Ms. Kanan Panchal (Ph.D. student). https://doi.org/10.1007/s13346-021-01060-y
Mr. Sumeet Katke (Ph.D. student) presented paper titled 'Formulation development and characterization of DNMT inhibitor loaded liposomes for the treatment of Pancreatic ductal adenocarcinoma (PDAC)' at the Controlled Release Society 2021 Virtual Annual Meeting July 25 - July 29, 2021.
Ms. Kanan Panchal (Ph.D. student) presented paper titled 'Development & characterization of BTK inhibitor loaded liposomes' at the Controlled Release Society 2021 Virtual Annual Meeting July 25 - July 29, 2021.
Ms. Kanan Panchal (Ph.D. student) was felicitated with 'Best M. Pharm Student 2020' award at Department of Pharmacy, BITS Hyderabad Campus.
Article published in International Immunopharmacology (Scopus Indexed; Impact factor: 5.714) entitled "Role of Targeted Immunotherapy for Pancreatic Ductal Adenocarcinoma (PDAC) Treatment: An Overview" authored by Ms. Kanan Panchal (Ph.D. student). https://doi.org/10.1016/j.intimp.2021.107508
Ms. Sucharitha Enakolla (M. Pharm. student) was awarded 'Tata Medical and Healthcare Scholarship' for the year 2020-21.
Ms. Kanan Panchal (Ph.D. student) has attended prestigious "Novartis Biotechnology Leadership Camp (BioCamp) 2021" during January 10-13 2021.