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Dr. Akash Chaurasiya 

Assistant Professor
Department of Pharmacy

Development of nano-particulate based carrier system for anticancer therapeutics delivery, Development of vesicular carrier system for enhancing drug efficacy and safety, Oral Bioavailability enhancement using novel approaches, Lyophilization Technique, Differentiated Product Development (505b2 based approaches), Cancer therapeutics, 505b2, Liposomes, Lipid Emulsion, LIpid Crystal, Formulation Development, Nanoparticles
Birla Institute of Technology & Science, Pilani
Hyderabad Campus
Jawahar Nagar, Kapra Mandal
Dist.-Medchal-500 078
Telangana, India

Former team members

  1.  Ms. Akhila M (M.Pharm - 2023) - Pursuing Ph.D. (NIPER Guwahati) India
  2.  Mr. Vishal Galave (M.Pharm - 2023) - Working in Jodas, Hyderabad, India
  3.  Mr. Harish Alladi (M.Pharm - 2023) - Anjamma healthcare pvt. ltd., Hyderabad, India
  4. Srushti Mhatre (M.Pharm - 2023)- Working in Aragen Life Sciences, Hyderabad, India
  5. Ms. Gauri Majage (M.Pharm - 2023) - Working in Pfizer, Chennai, India
  6. Mr. Shivam Narsikar (M.Pharm - 2023) - Working in Zydus, Ahmedabad, India
  7. Ms. Nikita Raheja (M. Pharm. - 2022) - Working in Biocon, Bengaluru, India
  8. Mr. Nikhil Lohar (M. Pharm. - 2022) - Working in Orbicular, Hyderabad, India
  9. Mr. Shubham Khanuja (B. Pharm. - 2022)
  10. Mr. Sanat Kumar Dash (Industry Sponsored Project)
  11. Ms. Hardi Parekh (M. Pharm. - 2022) - Working in Biocon, Bengaluru, India
  12. Mr. Rohan Sable (M. Pharm. - 2022) - Working in IQVIA, India
  13. Ms. Sucharitha Enakolla (M. Pharm. - 2022) - Working in Biocon, Bengaluru, India
  14. Ms. Aishwarya Shinde (M. Pharm. - 2021) - Working in Cipla, Mumbai, India
  15. Mr. Manan Doshi (M. Pharm. - 2021) - Working in Pfizer, Chennai, India
  16. Ms. Mrunali Mahalpure (M. Pharm. - 2021) - Working in Orbicular, Hyderabad, India
  17. Mr. Yatharth Agarwal (M. Pharm. - 2021) - Working in Jodas Expiom, Hyderabad, India
  18. Mr. Raghav Rathi (M. Pharm. - 2020) - Working in Pfizer, Chennai, India
  19. Ms. Tanishka Pruthi (M. Pharm. - 2020) -  Working in IQVIA, Bengaluru, India
  20. Ms. Pranathi Thathireddy (M. Pharm. - 2020) - Working in Aurigene Discovery, Hyderabad, India
  21. Ms. G. Pradeeptha Reddy  (M. Pharm. - 2020)
  22. Ms. Radhika Mahajan (M. Pharm. - 2019) - Pursuing Ph.D. at BITS Pilani - Hyderabad Campus, India
  23. Mr. Chiranjeev Singh (Industry Sponsored Project - 2020-21)

PhD Students

 
 
1.   Mr. Parameswar Patra
Ph.D. Student (ICMR SRF Fellow)
Research Area: Nanotechnology based approaches for Leukemia Therapy 
M. Pharm.: Roland Institute of Pharmaceutical Sciences, Berhampur, Orissa, India
 
Publications (TPRL Group):
  1. Akash Chaurasiya, Parameswar Patra, Pranathi Thathireddy, Amruta Gorajiya. “PLGA-based Micro- and Nano-particles: From Lab to Market”. In Micro- and Nanotechnologies-Based Product Development, CRC-Taylor & Francis. pp 83-95, 2021. 
    https://www.taylorfrancis.com/chapters/edit/10.1201/9781003043164-6/plga-based-micro-nano-particles-akash-chaurasiya-parameswar-patra-pranathi-thathireddy-amruta-gorajiya?context=ubx&refId=02cf4fa7-fa8f-45a1-be57-77ed7789533e
    https://doi.org/10.1201/9781003043164
  2. Ridahunlang Nongkhlaw, Parameswar Patra, Akash Chaurasiya, Nirmal Jayabalan, Sachin Dube, “Biologics: Delivery options and formulation strategies”. In Drug Delivery Aspects, Volume 4: Expectations and Realities of Multifunctional Drug Delivery Systems, Elsevier. pp 115-155, 2020.  https://doi.org/10.1016/B978-0-12-821222-6.00006-3
  3. Akash Chaurasiya, Parameswar Patra, Chiranjeev Singh and Manika Chourasiya, "Potential of nanotechnology based approaches for HIV/AIDS treatment", ISSRF Newsletter, Indian Society for the Study of Reproduction and Fertility, 26, 63-66 (2020).
  
 
 
 
 
 
 
2.   Mr. Sumeet Katke
Ph.D. Student (PDA Sponsored Project)
Research Area: Investigation of liposomal carrier system for anticancer drug delivery
M. Pharm.: BITS Pilani - Hyderabad Campus
 
Publications (TPRL Group):

  1. Tanisha Gupta, Rakesh Kumar Sahoo, Himani Singh, Sumeet Katke, Akash Chaurasiya, Umesh Gupta, "Lipid Based Nanocarriers in the Treatment of Glioblastoma (GBM): Challenges and Opportunities", AAPS PharmSciTech, 24, 102, 2023 - Published online:11 April 2023. (Impact Factor: 4.026).    https://link.springer.com/02555-2article/10.1208/s12249-023-                                                                            
  2. Sarita  Rani,  Rakesh Kumar Sahoo, Vinay Kumar, Akash Chaurasiya, Onkar Kulkarni, Ashutosh Mahale, Sumeet Katke, Kaushik Kuche, Vivek Yadav, Sanyog Jain, Kartik Nakhate, Ajazuddin, Umesh Gupta, “N-2-hydroxypropylmethacrylamide–polycaprolactone polymeric micelles in co-delivery of proteasome inhibitor and polyphenol: Exploration of synergism or antagonism”, Molecular Pharmaceutics, 20, 524-544, 2023. (Impact Factor: 5.364).
    https://doi.org/10.1021/acs.molpharmaceut.2c00752
  3. Akash Chaurasiya, Kanan Panchal, Sumeet Katke, Stable Oral Compositions of Posaconazole for Treating Fungal Infections, Indian Patent Authority, Application No. 202211001449, Application Submission Date: Jan 11 2022.
  4. Kanan Panchal, Sumeet Katke, Sanat Kumar Dash, Ankit Gaur, Aishwarya Shinde, Nithun Saha, Neelesh Kumar Mehra, Akash Chaurasiya, “An expanding horizon of complex injectable products: Development and regulatory considerations”, Drug Delivery & Translational Research, 13, 433-472, 2023. (Scopus indexed; Impact Factor: 5.671). https://doi.org/10.1007/s13346-022-01223-5
  5. Akash Chaurasiya, Amruta Gorajiya, Kanan Panchal, Sumeet Katke & Ajeet Kumar Singh, “A review on multivesicular liposomes for pharmaceutical applications: Preparation, characterization and translational challenges”, Drug Delivery & Translational Research, 12, 1569-1587, 2022. (Scopus indexed; Impact Factor: 5.671). https://doi.org/10.1007/s13346-021-01060-y 
  6. Aishwarya Shinde, Kanan Panchal, Sumeet Katke, Rishi Paliwal, Akash Chaurasiya, “Tyrosine kinase inhibitors as next generation oncological therapeutics: Current strategies, limitations and future perspective”, Therapies, 77, 425-443, 2022. (Scopus indexed; Impact Factor: 3.367).  https://doi.org/10.1016/j.therap.2021.10.010 
  7. Rishi Paliwal, Pramod Kumar, Akash Chaurasiya, Rameshroo Kenwat, Sumeet Katke, Shivani Rai Paliwal, “Development of nanomedicines and nanosimilars: Recent advances in regulatory landscape”, Current Pharmaceutical Design, 28, 165-177, 2022. (Impact Factor: 3.310).  https://doi.org/10.2174/1381612827666211115170001 
  8. Akash Chaurasiya, Sumeet Katke, Kanan Panchal & Nirmal Jayabalan “Biologics for the management of dementia”. In Nanomedicine-Based Approaches for the Treatment of Dementia, Elsevier. pp 193-234, 2022. https://doi.org/10.1016/B978-0-12-824331-2.00001-7
  9. Akash Chaurasiya, Sumeet Katke & Kanan Panchal “Nanotechnology-based approaches for Cancer Therapeutics”. In Nanomedicine, Nanotheranostics and Nanobiotechnology: Fundamentals and Applications, CRC - Taylor and Francis (In press). 2021.
 
 
 
 
 
 
 
3.   Ms. Kanan Panchal

Ph.D. Student (ICMR JRF Fellow)

Research Area: Development of liposomal carrier system for anticancer drug delivery

M. Pharm.: BITS Pilani - Hyderabad Campus

Novartis Bio-Camp 2021 Participant
 
Publications (TPRL Group):
 
  1. Kanan Panchal, Akhila Reddy, Rishi Paliwal, Akash Chaurasiya, "Dynamic intervention to enhance the stability of PEGylated Ibrutinib loaded lipidic nano-vesicular systems: transitioning from colloidal dispersion to lyophilized product"Drug Delivery and Translational Research, in press (Scopus indexed; Impact Factor: 5.4).
  2. Akash Chaurasiya, Sonali Singh, Kanan Panchal, Rishi Paliwal, Akanksha Malviya “ Fundamentals of targeted drug delivery system”.Molecular pharmaceutics and nano drug delivery: Fundamentals and Challenges, Elsevier. pp 289-309.https://doi.org/10.1016/B978-0-323-91924-1.00007-1 
  3. Rani, Sarita, Sahoo Rakesh Kumar, Mahale Ashutosh,  Panchal Kanan, Chaurasiya Akash, Kulkarni Onkar, Kuche Kaushik, Jain Sanyog, Nakhate Kartik Ajazuddin, Gupta Umesh, "Sialic Acid Engineered Prodrug Nanoparticles for Co-delivery of Bortezomib and Selenium in Tumor Bearing Mice"  Bioconjugate Chemistry Manuscript ID: bc-2023-00210n.R3                  
  4. Akash Chaurasiya, Kanan Panchal, Lipid Based Pharmaceutical Composition of BTK Inhibitor, Indian Patent Authority, Application No. 202211003679, Application Submission Date: Jan 22 2022.
  5. Akash Chaurasiya, Kanan Panchal, Sumeet Katke, Stable Oral Compositions of Posaconazole for Treating Fungal Infections, Indian Patent Authority, Application No. 202211001449, Application Submission Date: Jan 11 2022.
  6. Rachna M. Kumar, Hitesh Kumar, Tanvi Bhatt, Rupshee Jain, Kanan Panchal, Akash Chaurasiya, Vikas Jain, “Fisetin in Breast Cancer: Attributes, Developmental Aspects and Nanotherapeutics”, Pharmaceuticals, 16, 196, 2023. (Impact Factor: 5.215). https://doi.org/10.3390/ph16020196
  7. Kanan Panchal, Sumeet Katke, Sanat Kumar Dash, Ankit Gaur, Aishwarya Shinde, Nithun Saha, Neelesh Kumar Mehra, Akash Chaurasiya, “An expanding horizon of complex injectable products: Development and regulatory considerations”, Drug Delivery & Translational Research, 13, 433-472, 2023. (Scopus indexed; Impact Factor: 5.671). https://doi.org/10.1007/s13346-022-01223-5
  8. Kanan Panchal, Rakesh Kumar Sahoo, Umesh Gupta, Akash Chaurasiya, Role of Targeted Immunotherapy for Pancreatic Ductal Adenocarcinoma (PDAC) Treatment: An Overview, International Immunopharmacology, 95, 107508, 2021. (Scopus indexed; Impact Factor: 5.714). https://doi.org/10.1016/j.intimp.2021.107508
  9. Akash Chaurasiya, Amruta Gorajiya, Kanan Panchal, Sumeet Katke & Ajeet Kumar Singh, “A review on multivesicular liposomes for pharmaceutical applications: Preparation, characterization and translational challenges”, Drug Delivery & Translational Research, 12, 1569-1587, 2022. (Scopus indexed; Impact Factor: 5.671). https://doi.org/10.1007/s13346-021-01060-y 
  10. Aishwarya Shinde, Kanan Panchal, Sumeet Katke, Rishi Paliwal, Akash Chaurasiya, “Tyrosine kinase inhibitors as next generation oncological therapeutics: Current strategies, limitations and future perspective”, Therapies, 77, 425-443, 2022. (Scopus indexed; Impact Factor: 3.367). https://doi.org/10.1016/j.therap.2021.10.010 
  11. Akash Chaurasiya, Sumeet Katke, Kanan Panchal & Nirmal Jayabalan “Biologics for the management of dementia”. In Nanomedicine-Based Approaches for the treatment of Dementia, Elsevier. pp 193-234, 2022. https://doi.org/10.1016/B978-0-12-824331-2.00001-7
  12. Rishi Paliwal, Akash Chaurasiya, Kanan Panchal, Pooja Nayak, Nilosha Parveen & Shivani Rai Paliwal, “Engineering and functionalization of nanomaterials for theranostic applications in infectious diseases”. In Nanotheranostics for Treatment and Diagnosis of Infectious Diseases, Elsevier. pp 45-71, 2022. https://doi.org/10.1016/B978-0-323-91201-3.00003-7
  13. Akash Chaurasiya, Sumeet Katke & Kanan Panchal, “Nanotechnology-based approaches for Cancer Therapeutics”. In Nanomedicine, Nanotheranostics and Nanobiotechnology: Fundamentals and Applications, CRC - Taylor and Francis (In press), 2021. 
 
 
 
 
 
 
 
 
4.   Ms. Sonali Singh

Ph.D. Student

Research Area: Nanomedicine based approaches for tumor targeting
MS Pharm.: NIPER, Raebareli, UP, India
Project Trainee: CSIR-CDRI, Lucknow, UP, India
 
Publications (TPRL Group):
  1. Akash Chaurasiya, Sonali Singh, Kanan Panchal, Rishi Paliwal, Akanksha Malviya “ Fundamentals of targeted drug delivery system”.Molecular pharmaceutics and nano drug delivery: Fundamentals and Challenges, Elsevier. pp 289-309.https://doi.org/10.1016/B978-0-323-91924-1.00007-1 
 
 
 
 
 
 
5. Mr. Siddhant Padhi
Ph.D. Student 
Research Area: Nanocarrier mediated drug delivery for anticancer drugs
M. Pharm.: Manipal College of Pharmaceutical Sciences, MAHE, Manipal, India
 
 
 
 
 
 
 
 
 
 
6. Mr. Rahul Bhise
Sr. Manager - Slayback Pharma 
Ph.D. Student: Part time under Industrial Collaboration
Research Area: Complex injectables product development 
M. Pharm.: Manipal College of Pharmaceutical Sciences, MAHE, Manipal, India
 
 
 
 
 
 
7. Mr. Sushant Dube
Director - Slayback Pharma 
Ph.D. Student: Part time under Industrial Collaboration
Research Area: Development and evaluation of oral drug-loaded nanocarrier system for cancer treatment 
M. Pharm.: University Department of Pharmaceutical Sciences, Nagpur University, Maharashtra, India
 
Publications (TPRL Group):
  1. Sushant Omprakash Dube, Ajay Kumar Singh, Akash Chaurasiya, Chiranjeev Singh, Suprit Dilip Saoji, Pharmaceutical Combinations of Ibrutinib, Patent Application No. IN202041053973, Application Submission Date: Dec 11 2020.