Research Articles

1. Arundhoti Das, Gustavo Ulises Martinez-Ruiz, Nicolas Bouladoux, Apollo Stacy, Josquin Moraly, Maria Vega-Sendino, Yongge Zhao, Marieke Lavaert, Yi Ding, Abigail Morales-Sanchez, Christelle Harly, Mina O. Seedhom, Raj Chari, Parirokh Awasthi, Tomoko Ikeuchi, Yueqiang Wang, Jinfang Zhu, Niki M. Moutsopoulos, WanJun Chen, Jonathan W. Yewdell, Virginia Smith Shapiro, Sergio Ruiz, Naomi Taylor, Yasmine Belkaid, Avinash Bhandoola

“Transcription factor Tox2 is required for metabolic adaptation and tissue residency of ILC3 in the gut”

Immunity (2024): Immunity 2024 Volume 57, Issue 5, 14 May 2024, Pages 1019-1036.e9

https://www.sciencedirect.com/science/article/pii/S1074761324002061?via%3Dihub

2. Danish Umar*, Arundhoti Das*, Suman Gupta, Somdeb Chattopadhyay, Debayan Sarkar, Gauri Mirji, Jeet Kalia, Gopalakrishnan Aneeshkumar Arimbasseri, Jeannine Marie Durdik, Satyajit Rath, Anna George, Vineeta Bal

“Febrile temperature change modulates CD4 T cell differentiation via a TRPV channel-regulated Notch-dependent pathway”.

PNAS (2020): PNAS (2020) Sep8, 2020 117 (36) 22357-22366

*Joint first author

https://www.pnas.org/doi/full/10.1073/pnas.1922683117

3. Arundhoti Das, Vidya Ranganathan, Danish Umar, Shipra Thukral, Anna George, Satyajit Rath, Vineeta Bal

“Effector/memory CD4 T cells making either Th1 or Th2 cytokines commonly co-express T-bet and GATA-3”.

PLosONE (2017); Oct 31;12(10):e0185932

https://pubmed.ncbi.nlm.nih.gov/29088218/

4. Masaki Ishikawa, Zainul S Hasanali, Yongge Zhao, Arundhoti Das, Marieke Lavaert, Carly J. Roman, Jennifer Londregan, David Allman, Avinash Bhandoola

“The purinergic receptor P2RX4 sustains long-lived plasma cells by sensing extracellular ATP”

2024 Feb 14; 10.1038/s41586-024-07047-2

Nature (2024): Nature https://pubmed.ncbi.nlm.nih.gov/38355795/

5. Yi Ding, Marieke Lavaert, Simon Grassmann, Victor Band, Liang Chi, Arundhoti Das, Sumit Das, Christelle Harly, Susannah C. Shissler, Justin Malin, Yongge Zhao, Jinfang Zhu, Yasmine Belkaid, Joseph C. Sun, Avinash Bhandoola

"Different developmental pathways generate functionally distinct populations of natural killer cells"

Nature Immunology (2024): Nat Immuno. 2024 Jul;25(7):1183-1192. doi: 10.1038/s41590-024-01865-2

https://www.nature.com/articles/s41590-024-01865-2

6. Justin Malin*, Gustavo Ulises Martinez Ruiz*, Yongge Zhao*, Susannah C. Shissler, Jennifer E. Cowan, Yi Ding, Abigail Morales-Sanchez, Masaki Ishikawa, Marieke Lavaert, Arundhoti Das, Donna Butcher, Andrew C. Warner, Melissa Kallarakal, Jingqiu Chen, Avinash Bhandoola Noemi Kedei, Michael Kelly, Lauren R. Brinster, David Allman and

“Expression of the transcription factor Klf6 by thymic epithelial cells is required for thymus development”

Science Advances (2023): Sci Adv.2023 Nov

7. Rameez Raja, Chenyao Wang, Ritu Mishra, Arundhoti Das, Amjad Ali, Akhil C Banerjea

“Host AKT-mediated phosphorylation of HIV-1 accessory protein Vif potentiates infectivity via enhanced degradation of the restriction factor APOBEC3G”

Journal of Biological Chemistry (2022): JBC (2022) 298(4) 101805

https://pubmed.ncbi.nlm.nih.gov/35259395/

8. Daniel B Stamos, Lauren M Clubb, Apratim Mitra, Laura B Chopp, Jia Nie, Yi Ding, Arundhoti Das, Harini Venkataganesh, Jan Lee, Dalal El-Khoury, LiQi Li, Avinash Bhandoola, Remy Bosselut, Paul E Love

“The histone demethylase Lsd1 regulates multiple repressive gene programs during T cell development”

Journal of Experimental Medicine (2021): J Exp Med (2021) 218 (12): e20202012

https://pubmed.ncbi.nlm.nih.gov/34726730/

9. Maryam Ghaedi, Zi Yi Shen, Mona Orangi, Itziar Martinez-Gonzalez, LisaWei, Xiaoxiao Lu, Arundhoti Das, Alireza Heravi-Moussavi, Marco A. Marra, Avinash Bhandoola and Fumio Takei

“Single-cell analysis of RORα tracer mouse lung reveals ILC progenitors and effector ILC2 subsets”.

Journal of Experimental Medicine (2019): J Exp Med. 2020 Mar 2;217(3)

https://pubmed.ncbi.nlm.nih.gov/31816636/

10. Lara K. Abramowitz, Christelle Harly, Arundhoti Das, Avinash Bhandoola & John A. Hanover

“Blocked O-GlcNAc cycling disrupts mouse hematopoeitic stem cell maintenance and early T cell development”.

Scientific Reports (2019): Sci Rep (2019) 9:12569

https://www.nature.com/articles/s41598-019-48991-8

11. Hyungseok Seo, Joyce Chen, Edahí González-Avalos, Daniela Samaniego-Castruita, Arundhoti Das, Yueqiang H. Wang, Isaac F. López-Moyado, Romain O. Georges, Wade Zhang, Atsushi Onodera, Cheng-Jang Wuk, Li-Fan Luk, Patrick G. Hogan, Avinash Bhandoola and Anjana Rao

“TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8+ T cell exhaustion”.

PNAS (2019): Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12410-12415

https://www.pnas.org/doi/10.1073/pnas.1905675116

12. Amy P. Hsu, Agnes Donkó, Megan E. Arrington, Muthulekha Swamydas, Danielle Fink, Arundhoti Das, Omar Escobedo, Vincent Bonagura, Paul Szabolcs, Harry N. Steinberg, Jenna Bergerson, Amanda Skoskiewicz, Melanie Makhija, Joie Davis, Ladan Foruraghi, Cindy Palmer, Ramsay L. Fuleihan, Joseph A. Church, Avinash Bhandoola, Michail S. Lionakis, Sharon Campbell, Thomas L. Leto, Douglas Kuhns and Steven M. Holland

“Dominant activating RAC2 mutation with lymphopenia, immunodeficiency and cytoskeletal defects”.

Blood (2019): Blood. 2019 May 2;133(18):1977-1988

https://ashpublications.org/blood/article/133/18/1977/260465/Dominant-activating RAC2-mutation-with-lymphopenia

13. Sanket Rane, Rituparna Das, Vidya Ranganathan, Savit Prabhu, Arundhoti Das, Hamid Mattoo, Jeannine Durdik, Anna George, Satyajit Rath, Vineeta Bal

“Peripheral residence of naïve CD4 T cells induces MHC class II-dependent alterations in phenotype and function”.

BMC Biology (2014); 12(1): 106.

https://pubmed.ncbi.nlm.nih.gov/25528158/

Reviews

1. Arundhoti Das, Christelle Harly, Qi Yang, Avinash Bhandoola

“Lineage specification in innate lymphocytes”.

Cytokine and Growth Factor Reviews (2018): Volume 42, August 2018, Pages 20-26

https://www.sciencedirect.com/science/article/pii/S1359610117301946

Book Chapters

1. Arundhoti Das, Christelle Harly, Yi Ding, Avinash Bhandoola

“ILC Differentiation from Progenitors in the Bone Marrow”.

Springer, Nature (2022): Book Chapter, Book: Innate Lymphoid Cells

https://pubmed.ncbi.nlm.nih.gov/35567738/

2. Yi Ding, Christelle Harly, Arundhoti Das, Avinash Bhandoola

“Early development of Innate Lymphoid Cells”.

Methods in molecular biology (2022)

https://pubmed.ncbi.nlm.nih.gov/36374450/