Assistant Professor
Department of Biological Sciences
Publications:
Jayaprakash JP, Sridhanya VM, Khandelia P* (2025). Tumor‑suppressive role of m6A eraser proteins FTO and ALKBH5 in oral squamous cell carcinoma. The Nucleus. https://doi.org/10.1007/s13237-025-00566-x. (*Corresponding Author)
Jayaprakash JP, Karemore P, Khandelia P* (2025). METTL3 promotes oral squamous cell carcinoma by regulating miR-146a-5p/SMAD4 axis. Oncotarget. May 8;16:291-309. doi: 10.18632/oncotarget.28717. (*Corresponding Author)
Saravanan L, Mahale A, Gota V, Khandelia P, Kulkarni OP. (2025). Necrostatin-1 attenuates oral squamous cell carcinoma by modulating tumour immune response in mice. Fundam Clin Pharmacol. Jun;39(3):e70008. doi: 10.1111/fcp.70008.
Satya Sri Kotipalli, R., Sharma, M., Siva Kumar, N., Kumar, A., Dhiman, C., Rawat, M., Khandelia P, Pranav Narayan, K. (2025). Targeting Cancer Stem Cells in Gynecological Malignancies: Emerging Advanced Therapeutic Approaches. IntechOpen. doi: 10.5772/intechopen.1007910.
Janakiraman, P., Jayaprakash, J. P., Muralidharan, S. V., Narayan, K. P., Khandelia, P* (2024). N6-methyladenosine RNA modification in head and neck squamous cell carcinoma (HNSCC): current status and future insights. Medical oncology (Northwood, London, England), 42(1), 12. https://doi.org/10.1007/s12032-024-02566-4. (*Corresponding Author)
Bhattacharya, D., Bharati, M. R., Sakhare, K., Khandelia, P., Banerjee, R., & Narayan, K. P. (2024). Steroid hormone receptor based gene delivery systems as potential oral cancer therapeutics. Biomedical materials (Bristol, England), 19(2), 10.1088/1748-605X/ad2407. https://doi.org/10.1088/1748-605X/ad2407.
Jalan, A., Jayasree, P. J., Karemore, P., Narayan, K. P., Khandelia, P* (2024). Decoding the 'Fifth' Nucleotide: Impact of RNA Pseudouridylation on Gene Expression and Human Disease. Molecular biotechnology, 66(7), 1581–1598. https://doi.org/10.1007/s12033-023-00792-1 (*Corresponding Author)
Karemore, P., Jayaprakash, J.P., Narayan, K.P., Khandelia P* (2024). Regulatory crosstalk between TGF-β signaling and miRNAs: a head and neck cancer perspective. The Nucleus . https://doi.org/10.1007/s13237-024-00499-x. (*Corresponding Author)
Jayasree, P. J., Dutta, S., Karemore, P., Khandelia, P* (2024). Crosstalk Between m6A RNA Methylation and miRNA Biogenesis in Cancer: An Unholy Nexus. Molecular biotechnology, 66(11), 3042–3058. https://doi.org/10.1007/s12033-023-00921-w. (*Corresponding Author)
Priyadarshini, N., Venkatarama Puppala, N., Jayaprakash, J. P., Khandelia, P., Sharma, V., & Mohannath, G. (2023). Downregulation of ribosomal RNA (rRNA) genes in human head and neck squamous cell carcinoma (HNSCC) cells correlates with rDNA promoter hypermethylation. Gene, 888, 147793. https://doi.org/10.1016/j.gene.2023.147793.
Karthiya, R., Wasil, S. M., Khandelia, P* (2020). Emerging role of N4-acetylcytidine modification of RNA in gene regulation and cellular functions. Molecular biology reports, 47(11), 9189–9199. https://doi.org/10.1007/s11033-020-05963-w. (*Corresponding Author)
Rajappa, A., Banerjee, S., Sharma, V., Khandelia, P* (2020). Circular RNAs: Emerging Role in Cancer Diagnostics and Therapeutics. Frontiers in molecular biosciences, 7, 577938. https://doi.org/10.3389/fmolb.2020.577938. (*Corresponding Author)
Karthiya, R., & Khandelia, P* (2020). m6A RNA Methylation: Ramifications for Gene Expression and Human Health. Molecular Biotechnology, 62(10), 467–484. https://doi.org/10.1007/s12033-020-00269-5. (*Corresponding Author)
Vijaykrishna N, Melangath G, Kumar R, Khandelia P, Bawa P, Varadarajan R, Vijayraghavan U (2016) The fission yeast pre-mRNA processing factor spprp18+ has intron-specific splicing functions with links to G1-S cell cycle progression. Journal of Biological Chemistry, 291(53): 27387-401.
Neo WH, Yap K, Lee SH, Looi LS, Khandelia P, Neo SX, Makeyev EV, Su IH (2014) Micro RNA miR-124 controls the choice between neuronal and astrocyte differentiation by fine-tuning Ezh2 expression. Journal of Biological Chemistry, 289(30): 20788-801.
*Banerjee S, *Khandelia P, Melangath G, Bashir S, Vijaykrishna N, Vijayraghavan U (2013) Splicing functions and global dependency on fission yeast SpSlu7 reveal diversity in spliceosome assembly. Molecular and Cellular Biology, 33(16): 3125-36. (*equal first author)
*Yap K, *Lim ZQ, *Khandelia P, Friedman B, Makeyev EV (2012) Coordinated regulation of neuronal mRNA steady-state levels through developmentally controlled intron retention. Genes and Development, 26(11): 1209-23. (*equal first author)
Juvvuna PK, Khandelia P, Lee LM, Makeyev EV (2012) Argonaute identity defines the length of mature mammalian microRNAs. Nucleic Acids Research, 40(14): 6808-20.
Saha D, Khandelia P, O'Keefe RT, Vijayraghavan U (2012) Saccharomyces cerevisiae NineTeen complex (NTC)-associated factor Bud31/Ycr063w assembles on precatalytic spliceosomes and improves first and second step pre-mRNA splicing efficiency. Journal of Biological Chemistry, 287(8): 5390-9.
Khandelia P, Yap K, Makeyev EV (2011) Streamlined platform for short hairpin RNA interference and transgenesis in cultured mammalian cells. Proceedings of the National Academy of Sciences USA, 108(31): 12799-804.
*Sapra AK, *Khandelia P, Vijayraghavan U. (2008) The splicing factor Prp17 interacts with the U2, U5 and U6 snRNPs and associates with the spliceosome pre- and post-catalysis. Biochemical Journal, 416(3):365-74. (*equal first author)
Sapra AK, Arava Y, Khandelia P, Vijayraghavan U (2004) Genome-wide analysis of pre-mRNA splicing: intron features govern the requirement for the second-step factor, Prp17 in Saccharomyces cerevisiae and Schizosaccharomyces pombe. Journal of Biological Chemistry, 279(50):52437-46.
This website uses cookies or similar technologies, to enhance your browsing experience.