Dr. Piyush Khandelia

Assistant Professor
Department of Biological Sciences

Role of RNA epigenetics and regulatory RNAs in regulation of skeletal myogenesis and oral cancer
Birla Institute of Technology & Science, Pilani
Hyderabad Campus
Jawahar Nagar, Kapra Mandal
Dist.-Medchal-500 078
Telangana, India


From BITS:

1. Karthiya R, Khandelia P*. m6A RNA Methylation: Ramifications for Gene Expression and Human Health. Mol Biotechnol. 2020 Oct;62(10):467-484. doi: 10.1007/s12033-020-00269-5. (*Corresponding Author) (IF: 2.86) (Scopus Indexed)

2. Rajappa A, Banerjee S, Sharma V*, Khandelia P*. Circular RNAs: Emerging Role in Cancer Diagnostics and Therapeutics. Front Mol Biosci. 2020 Oct 28;7:577938. doi: 10.3389/fmolb.2020.577938. (*Corresponding Author) (IF: 4.188) (Scopus Indexed)

3. Karthiya R, Wasil SM, Khandelia P*. Emerging role of N4-acetylcytidine modification of RNA in gene regulation and cellular functions. Mol Biol Rep. 2020 Nov;47(11):9189-9199. doi: 10.1007/s11033-020-05963-w. (*Corresponding Author) (IF: 2.3) (Scopus Indexed) 
4. Priyadarshini N, Venkatarama Puppala N, Jayaprakash JP, Khandelia P, Sharma V and Mohannath G. Downregulation of ribosomal RNA (rRNA) genes in human head and neck squamous cell carcinoma (HNSCC) cells correlates with rDNA promoter hypermethylation. Gene. 2023 Dec 20;888:147793. doi: 10.1016/j.gene.2023.147793. (IF: 3.5) (Scopus Indexed)
5. Jayasree PJ, Dutta S, Karemore P, Khandelia P*. Crosstalk Between m6A RNA Methylation and miRNA Biogenesis in Cancer: An Unholy Nexus. Mol Biotechnol. 2023 Oct 13. doi: 10.1007/s12033-023-00921-w. (IF: 2.86) (Scopus Indexed) 
6. Jalan A, Jayasree PJ, Karemore P, Narayan KP, Khandelia P*. Decoding the 'Fifth' Nucleotide: Impact of RNA Pseudouridylation on Gene Expression and Human Disease. Mol Biotechnol. 2023 Jun 21. doi: 10.1007/s12033-023-00792-1. (IF: 2.86) (Scopus Indexed)

Before BITS:

1. Vijaykrishna N, Melangath G, Kumar R, Khandelia P, Bawa P, Varadarajan R, Vijayraghavan U (2016) The fission yeast pre-mRNA processing factor spprp18+ has intron-specific splicing functions with links to G1-S cell cycle progression. Journal of Biological Chemistry, 291(53): 27387-401. 

2. Neo WH, Yap K, Lee SH, Looi LS, Khandelia P, Neo SX, Makeyev EV, Su IH (2014) Micro RNA miR-124 controls the choice between neuronal and astrocyte differentiation by fine-tuning Ezh2 expression. Journal of Biological Chemistry, 289(30): 20788-801.  

3.*Banerjee S, *Khandelia P, Melangath G, Bashir S, Vijaykrishna N, Vijayraghavan U (2013) Splicing functions and global dependency on fission yeast SpSlu7 reveal diversity in spliceosome assembly. Molecular and Cellular Biology, 33(16): 3125-36. (*equal first author)

4.*Yap K, *Lim ZQ, *Khandelia P, Friedman B, Makeyev EV (2012) Coordinated regulation of neuronal mRNA steady-state levels through developmentally controlled intron retention. Genes and Development, 26(11): 1209-23. (*equal first author)

5. Juvvuna PK, Khandelia P, Lee LM, Makeyev EV (2012) Argonaute identity defines the length of mature mammalian microRNAs. Nucleic Acids Research, 40(14): 6808-20. 

6. Saha D, Khandelia P, O'Keefe RT, Vijayraghavan U (2012) Saccharomyces cerevisiae NineTeen complex (NTC)-associated factor Bud31/Ycr063w assembles on precatalytic spliceosomes and improves first and second step pre-mRNA splicing efficiency. Journal of Biological Chemistry, 287(8): 5390-9. 

7. Khandelia P, Yap K, Makeyev EV (2011) Streamlined platform for short hairpin RNA interference and transgenesis in cultured mammalian cells. Proceedings of the National Academy of Sciences USA, 108(31): 12799-804. 

8.*Sapra AK, *Khandelia P, Vijayraghavan U. (2008) The splicing factor Prp17 interacts with the U2, U5 and U6 snRNPs and associates with the spliceosome pre- and post-catalysis. Biochemical Journal, 416(3):365-74. (*equal first author) 

9. Sapra AK, Arava Y, Khandelia P, Vijayraghavan U (2004) Genome-wide analysis of pre-mRNA splicing: intron features govern the requirement for the second-step factor, Prp17 in Saccharomyces cerevisiae and Schizosaccharomyces pombe. Journal of Biological Chemistry, 279(50):52437-46.