Prof. A Sajeli Begum

Head & Professor
Department of Pharmacy

Birla Institute of Technology & Science, Pilani
Hyderabad Campus
Jawahar Nagar, Kapra Mandal
Dist.-Medchal-500 078
Telangana, India

P. Singh, A.K. Singh, A. Sajeli Begum and M. Sahai., “Two Acyl sucroses from Petunia nyctaginiflora”, Phytochemistry, 2003, 63(4), 485-489. 

Sajeli Begum, A.P. Singh, M. Singh and M. Sahai, “Chemical constituents of Polyalthia suberosa Thw.”  J. Ind. Chem. Soc, 2004, 81(1), 71-72. 

Sajeli Begum, U.K. Rai., S. Singh and M. Sahai, “New pairs of acyl sucroses from Petunia nyctaginiflora” J. Ind. Chem. Soc., 2004, 81(6), 495-500.

 Sajeli Begum, Ajay. P. Singh, M. Sahai, S. Singh, Y. Fujimoto, “Two novel Acyl sucroses from Petunia nyctaginiflora. Juss” Indian J. Chem. (Sec B), 2005, 44B, 648-650.

Sajeli Begum A., Sahai M., Fujimoto Y., Schneider K., Nicholson G., Suessmuth R.D., “A New Kaempferol glycoside from Datura suaveolens Humb & Bonpl. ex Willd” Natural Product Research, 2006, 20 (13), 1231-1236.

Sajeli B. A., Sahai M, Suessmuth R, Teigo Asai, Yoshinori Fujimoto, “Hyosygerin, a new optically active coumarinolignan from the seeds of Hyoscyamus niger” Chem. Pharm. Bull., 2006, 54 (4), 538-541.

 Sajeli B. Akhil, M. Sahai, Teigo Asai, Noriyuki Hara, Y. Fujimoto. “Hyosmin, a new Lignan from Hyoscyamus niger Linn.”  J. Chem. Research, 2006, 10, 675-677.

Sajeli Begum* and Madhur Goyal, “A Review on Research and Medicinal Potential of Cestrum”. Pharmacognosy Reviews, 2007, Vol. 1, Issue 2, Jul-Dec, 320-332.

Sajeli Begum*, Shweta Verma, Mahendra Sahai, Kathrin Schneider and Roderich Süssmuth, “Hyoscyamal, A New Tetrahydrofuranic Lignan from Hyoscyamus niger Linn”, Natural Product Research, 2009, 23 (7), 595-600.

 Sajeli Begum A*., Saxena B, Goyal M, Sairam K., Ch Rao, Ranjan R and Sahai M., “Study of anti-inflammatory, analgesic and anti-pyretic activities of seeds of Hyoscyamus niger L. and isolation of a new coumarinolignan”, Fitoterapia, 2010, 81, 178-184.

 Sajeli Begum*, “Bioactive non-alkaloidal secondary metabolites of Hyoscyamus niger Linn. Seeds – A Review”, Research Journal of Seed Science, 2010, 3 (4), 210-217.

 Sajeli Begum*, Madhur Goyal, “Study of antioxidant and hepatoprotective activities of standardized Cestrum diurnum leaf extract” Ethnopharmacology, 2010, Vol 1 (1).

Alvala Ravi, A. Mallika, Venkatesh Sama, A. Sajeli Begum, Rukaiyya S. Khan, B. Madhava Reddy, “Antiproliferative activity and standardization of Tecomella undulate bark extract on K562 cells” Journal of Ethnopharmacology, 2011, Vol 137, 1353-1359.

Sajeli Begum*, Angela Patnaik, S. Ameer Basha, G. Raghavendra, S. K. Pandey and B. K. Sharma, “Effect of leaf extract and steroidal saponin of Cestrum diurnum L. on spore germination and mycelial growth of some fungi” EJEAF Che, 2011, 10(11), 3097-3103.

G. Raghavendra, S. Ameer Basha, M. V. Nagesh Kumar, K. Dharma Reddy, Sajeli Begum*, S. Mahibalan, C. V. Sameer Kumar and M.Suresh, “Effect of safflower petal extraction on spore germination of sorghum grain mold fungi”, J. Oilseeds Res., 2012, 29 (Spl. Issue), 329-332.

S. Mahibalan, A. Sajeli Begum*, S. Ameer Basha and C. V. Sameer Kumar, “Quality control studies on non-spiny hybrid safflower petals as per World Health Organisation (WHO) requirement” J. Oilseeds Res., 2012, 29 (Spl. Issue), 452-455.

Araya, H.; Maeda, U.; Hara, N.; Prasad, S.; Begum, A. S.; Sahai, M.; Fujimoto, Y. Potent biologically active tetrahydrofuranic acetogenins from custard apple (Annona reticulate Linn) seeds. Meiji Daigaku Nogakubu Kenkyu Hokoku, 2012, 62 (1), 1-9.

Deepali pandey, S. K. Prasad, A. Sajeli Begum, S. Hemalatha and A. K. Wahi, Pharmacognistical standardization and isolation of ergosterol from Melothria maderaspatana Linn. International Journal of Food Properties, 2013, 16 (8), 1871-1882.

S. Mahibalan, Ruben Sharma, Aditya Vyas, S.  Ameer Basha and A. Sajeli Begum*, “Assessment of extraction techniques for total phenolics and flavonoids from Annona muricata seeds” Journal of Indian Chemical Society, 2013, Dec vol 90, 1-7.

Shaik Ameer Basha, Sajeli Begum*, Raghavendra, Subba Rao, “Sensitivity of Pseudomonas fluorescens and Rhizobium to various antibiotics under in vitro” International Journal of Bioresource and Stress Management”, 2013, Vol 4 (4), 487-491

Sajeli Begum*, Ameer Basha, G. Raghavendra, M. V. Nagesh Kumar , Yukthi Singh, Jagannath V Patil, Yuhei Tanemura, and Yoshinori Fujimoto, “Isolation and characterization of antimicrobial compounds from Pseudomonas fluorescence and their efficacy on sorghum grain mold fungi” Chemistry and BioDiversity, 2014, Vol 11 (1), 92-100.

Ameer Basha, Sajeli Begum*, Raghavendra, “Effect of various extracts of Annona muricata, Abutilon indicum and Evolvulus alsinoides extract on spore germination of sorghum grain mold fungi” Int. J. Bioresource and Stress Management. 2014, Vol 5(1), 102-106.

Ameer Basha, Sajeli Begum*, Ragavendra, “Search for agrochemical and heavy metal tolerant strains of Pseudomonas fluorescens and Rhizobium” Indian Journal of Plant Protection 2014, 42 (1), 71-77.

S. Mahibalan, A. Sajeli Begum*, Ravi Sojitra, S. Ameer Basha, Sameer K.  Chandavenkata and C. Sudhakar “Physico-Chemical Characterization of Spineless Safflower Petals and HPLC-Based Process Optimization for Extracting Quercetin-3-O-rutinoside” Journal of Indian Chemical Society, 2014, 91, 1-9.

Sajeli Begum Ahil*, Senthi Mahibalan, Shaik Ameer Basha, Ramesh Babu and Katragadda Suresh Babu “Comparative pharmacognostic evaluation and HPTLC analysis of petals of spiny and non-spiny safflower cultivars” 2015, International Journal of Food Properties, 2015, 18 (11), 2561-2570. DOI: 10.1080/10942912.2014.988722

Rukaiyya Sirajuddin Khan, Mahibalan Senthi, Poorna Chandra Rao, Ameer Basha, Mallika Alvala, Dinesh Tummuri, Hironori Masubuti, Yoshinori Fujimoto, Ahil Sajeli Begum*, “Antiproliferative constituents of Abutilon indicum leaves against U87MG human glioblastoma cells” Natural Product Research, 2015, 29 (11), 1069-1073. DOI: 10.1080/14786419.2014.976643. [IF 2.0]

Rukaiyya Khan, Ameer Basha, Goverdhanam Ragavendra, Poorna Chandra Rao, Yuhei Tanemura, Yoshinori Fujimoto, Ahil Sajeli Begum*, “Attenuation of TNF-α secretion by L-proline-based cyclic dipeptides produced by culture broth of Pseudomonas aeruginosa” Bioorganic and Medicinal Chemistry Letters, 2015, Dec 15;25(24), 5756-61. doi:10.1016/j.bmcl.2015.10.075 [IF 2.572]

Senthi Mahibalan, Poorna Chandra Rao, Rukaiyya Khan, Ameer Basha, Ramakrishna Siddareddy,  Hironori Masubuti, Yoshinori Fujimoto, Ahil Sajeli Begum*, “Cytotoxic constituents of Oldenlandia umbellata and isolation of a new symmetrical coumarin dimer” Medicinal Chemistry Research, 2016, 25, 466-472. DOI: 10.1007/s00044-015-1500-z. [IF 1.783]

P.C. Rao, M.F. J. Ali, Z. H. Jahromi, Saketh S, Sahai M, Ahil Sajeli Begum*, “Cytotoxicity of withasteroids: withametelin induces cell cycle arrest at G2/M phase and mitochondria mediated apoptosis in Non-small cell lung cancer A549 cells” Tumor Biology, 2016, 37, 9, 12579-587, DOI: 10.1007/s13277-016-5128-5 [IF 3.650]

S Mahibalan, Maria Stephen, T N Rohan, Rukaiyya S Khan, A Sajeli Begum*, “Dermal wound healing potential of betaine and standardized alkaloid enriched ointment of Evolvulus alsinoides in albino rats” Pharmaceutical Biology, 2016, 54(12), 2851-56 (DOI:  10.1080/13880209.2016.1185636). [IF 2.971]

Ameer Basha, Sajeli Begum*, Govardhanam Ragavendra, Mahibalan Senthi, Rukaiyya Khan, Ravi Sojitra, Santhosh Kumar, Asalla  Srinivas, “Antifungal effect and protective role of ursolic acid and three phenolic derivatives in the management of Sorghum grain mold under field conditions” Chemistry and BioDiversity, 2016, 13(9), 1158-1164. doi: 10.1002/cbdv.201500515. [IF 2.039]

Pabbati Sanjana, Hira Kirti and Sajeli Begum*. “Medical devices and their approval procedure in India” Int. J. Drug Reg. Affairs 2016, 4(3), 19-29 (DOI:

Poorna Rao, Sajeli Begum*, Mahendra Sahai, Saketh Sriram, “Coptisine, a tetraoxygenated protoberberine alkaloid induces cell cycle arrest at G2/M phase and ROS-dependent mitochondria mediated apoptosis in Non-small cell lung cancer A549 cells” Tumor Biology, 2017, 39 (3), DOI: [IF 3.650]

Kirti Hira, Ameer Basha, Santosh Kumar, Sajeli Begum Ahil*. “Pseudomonas – a potential source for drug lead discovery” Current Trends in Biomedical Engineering and Biosciences, 2017, 5(5), 555674. DOI: 10.19080/CTBEB.2017.05.555674 [IF 0.822]

Ahil Sajeli Begum*, Santosh Kumar, Suryanarayana G, Kirti Hira. “O-Glucoside of natural cleomiscosin-A: An attenuator of pro-inflammatory cytokine production” Phytochemistry Letters, 2018, 26, 83-87. [IF 3.044]

A. Sajeli Begum*, S. Santhosh Kumar. “Advances in the chemistry and pharmacological potential of coumarinolignans” Topics in Current Chemistry, 2018, 376:34. [IF 7.455]

Jeyapragash D., Saravana Kumar A., Santosh Kumar S., Sajeli Begum A. “GC-MS Based Metabolomics Analysis and Characterization of Rosmarinic Acid from Tropical Seagrass” International J. Pharmaceutical Research, 2018, 10(4), 277-285. [SJR 2019 Q2]

Ameer Basha, S., Sajeli Begum, A*. and Ragavendra, G., Biochemical Characterization of Native Pseudomonas fluorescens Strains followed by their Compatibility with Agrochemicals and Phyto-extracts under in vitro, Int. J. Pure App. Biosci. 2018, 6(6): 117-124. doi:

S. Santhosh Kumar, Ahil Sajeli Begum*, Kirti Hira, Sarfaraj Niazi, B.R. Parshantha Kumar, Hiroshi Araya and Yoshinori Fujimoto. Structure-based design and synthesis of new 4-methylcoumarin-based lignans as pro-inflammatory cytokines (TNF-, IL-6 and IL-1) inhibitors. Bioorganic Chemistry, 2019, 89, 102991, DOI 10.1016/j.bioorg.2019.102991 {IF 4.831]

A. Sajeli Begum*, Kirti Hira, Ameer Basha Shaik, Pragya P. P., Onkar P. Kulkarni, H. Araya and Y. Fujimoto. l-Proline-based-cyclic dipeptides from Pseudomonas sp. (ABS-36) inhibit pro-inflammatory cytokines and alleviate crystal-induced renal injury in mice. International Immunopharmacology, 2019, 73, 395-404. [IF 3.943]

A. Sajeli Begum*, Swati Alok and Samrun Nessa. Larval Survey and Spatial Epidemiological Analysis of Vector Aedes aegypti to Study the Risk of Dengue Outbreak in India. GeoJournal, 2019, DOI: 10.1007/s10708-019-10060-y [SJR 2019 0.46, Q2]

Ameer Basha Shaik, Sajeli Begum Ahil*, Ragavendra Govardhan & Pragya Paramita Pal. Management of sorghum grain mold through induced resistance mechanism using foliar spray of Pseudomonas fluorescens strains and non-conventional chemicals: a field study. Archives of Phytopathology and Plant Protection, 2019, 52:11-12, 969-988 [Indexed, SJR 2019 0.23, Q3].

Swati Alok, Samrun Nessa Sajeli Begum Ahil*. School training strategies for prevention and control of Dengue. Indian J Community Med., 2020, 45 (1), 106-107 [Indexed, SJR 2019 0.3, Q3].

Pragya P. Paul, Ameer Basha S., Sajeli Begum Ahil*. Prospective leads from endophytic fungi for anti-inflammatory drug discovery. Planta Medica, 2020, DOI [IF 2.687]

Santhosh S Kumar, Kirti Hira, Sajeli Begum Ahil*, Onkar P Kulkarni, Hiroshi Araya and Yoshinori Fujimoto. New Synthetic Coumarinolignans as Attenuator of Pro-Inflammatory Cytokines under LPS-Induced Sepsis and Carrageenan-Induced Paw Oedema Models. Inflammopharmacology, 2020, [IF 3.238]

Sajeli Ahil Begum*, Kirti Hira, Pragya Paramita Pal, Samrun Nessa, Onkar P. Kulkarni, Jeyapragash Danaraj, Ameer Basha Shaik, Hiroshi Araya, Yoshinori Fujimoto. Halodule pinifolia (Seagrass) attenuated lipopolysaccharide-, carrageenan- and crystal-induced secretion of pro-inflammatory cytokines: Mechanism and Chemistry. Inflammopharmacology, 2020, DOI 10.1007/s10787-020-00747-x [IF 3.238]

Swati Alok, Samrun Nessa and Sajeli Begum. Will she wont she: determinants of complementary and alternative medicines use among female rheumatoid arthritis patients. Advances in Traditional Medicine, 2021,

Lakshmi PS Soukya and Sajeli A Begum*. Review on target domains and natural compound-based inhibitors of fatty acid synthase for anti-cancer drug discovery. Chemical Biology and Drug Design, 2021, doi:10.1111/cbdd.13942 [IF 2.817]

Kirti Hira, Pravesh Sharma, Ashutosh Mahale, Onkar P. Kulkarni, A. Sajeli Begum*. Cyclo(Val-Pro) and Cyclo(Leu-Hydroxy-Pro) from Pseudomonas sp. (ABS-36) alleviates acute and chronic renal injury under in vitro and in vivo models (Ischemic reperfusion and unilateral ureter obstruction). International Immunopharmacology, 2022, vol 103, 108494, [IF 4.932]

Purbali C., Sajeli Begum A., Trinath J., Yogeeswari P. Combining structure-based and 3D QSAR pharmacophore models to discover diverse ligands against EGFR in oral cancer. Future Medicinal Chemistry, 15 Feb 2022, [IF 3.808]

Nikitha Lakshmi; Ameer Basha Shaik; Pragya Paramita Pal; Sajeli Begum Ahil; Ramya Vittal; Saida Naik; Uma Devi Gali; Vidya Sagar Bokka. Piperine, reserpine and b-sitosterol attenuate stem rot (Sclerotium rolfsii Sacc.) of groundnut by inducing the secretion of defense enzymes and phenolic acids. Chemistry and Biodiversity, 19 February 2022, [IF 2.408]

Pragya Paramita Pal, Ahil Sajeli Begum*, Shaik Ameer Basha, Hiroshi Araya and Yoshinori Fujimoto. A new lignan (Polonilignan) and inhibitors of nitric oxide production from Penicillium polonicum, an endophytic fungi of Piper nigrum. Chemistry and Biodiversity, 20 Jan 2023, [2.745]

Pragya Paramita Pal, Ahil Sajeli Begum*, Shaik Ameer Basha, Hiroshi Araya and Yoshinori Fujimoto. New natural pro-inflammatory cytokines (TNF-α, IL-6 and IL-1β) and iNOS inhibitors identified from Penicillium polonicum through in vitro and in vivo studies. International Immunopharmacology, Apr;117:109940. doi: 10.1016/j.intimp.2023.1099402023 [IF 5.714]

Sajeli A. Begum and Ahmed Kamal. What are the challenges involved in the strategies for future antibody-drug conjugate discovery and development for oncology? Expert Opinion on Drug Discovery, Apr 2023, [IF 7.05]