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Prof. Akash Chaurasiya 

Associate Professor,
Department of Pharmacy

Advanced lyophilization technique, Cancer therapeutics, Development of nano-particulate/vesicular carrier system for enhancing drug efficacy and safety, Differentiated product development (505b2 based approaches), Lipid Emulsion, Liposomes, Oral Bioavailability enhancement using novel approaches, Parenteral Products
Birla Institute of Technology & Science, Pilani
Hyderabad Campus
Jawahar Nagar, Kapra Mandal
Dist.-Medchal-500 078
Telangana, India

Publications

After joining BITS Pilani (DPIL)

  1. Kumar, A., Dhiman, C., Nimbarte, V. D., Erukulla, P., Bharati, M. R., Chattopadhyay, R., Mukherjee, A., Chaurasiya, A., & Narayan, K. P. (2026). A polyherbal and probiotic-based immunostimulatory formulation for managing gut dysbiosis in colorectal cancer. Frontiers in nutrition, 13, 1854998. https://doi.org/10.3389/fnut.2026.1854998
  2. Panchal, K., Pillai, Y., Paliwal, R., & Chaurasiya, A. (2026). Extending the Frontiers of Lyophilization of Carfilzomib-Loaded PEGylated liposomes: A thorough Investigation on Formulation Development and Manufacturing Process. Journal of Pharmaceutical Innovation, 22(1). https://doi.org/10.1007/s12247-026-10994-0
  3. Singh, S., Panchal, K., Galave, V. B., Mahale, A., Kulkarni, O. P., & Chaurasiya, A. (2026). Development and optimization of lipid emulsion based therapeutic system targeting vascular endothelial growth factor receptor for non-small cell lung cancer treatment. BioNanoScience, 16(4). https://doi.org/10.1007/s12668-026-02466-z
  4. Katke, S., Singh, S., Padhi, S., Sakhare, K., Narayan, K. P., & Chaurasiya, A. (2026). Development and evaluation of DNA Methyltransferase Inhibitor-Loaded liposomes as a new frontier in pancreatic ductal adenocarcinoma therapy. Journal of Pharmaceutical Innovation, 21(2). https://doi.org/10.1007/s12247-025-10243-w
  5. Katke, S., Panchal, K., Singh, S., Padhi, S., Sakhare, K., Narayan, K. P., & Chaurasiya, A. (2026). Development of DNA methyltransferase inhibitor loaded surface engineered copolymeric nanoparticles for pancreatic ductal adenocarcinoma treatment: optimization, characterization, and preclinical evaluation. BioNanoScience, 16(2). https://doi.org/10.1007/s12668-025-02292-9
  6. Padhi, S., Panchal, K., Pillai, Y., & Chaurasiya, A. (2025). Exploring novel approaches to develop an efficient lyophilization process for the stabilization of Drug-Loaded colloidal liposomes. Journal of Pharmaceutical Innovation, 20(6). https://doi.org/10.1007/s12247-025-10139-9
  7. Panchal, K., Reddy, A., Paliwal, R., & Chaurasiya, A. (2024). Dynamic intervention to enhance the stability of PEGylated Ibrutinib loaded lipidic nano-vesicular systems: transitioning from colloidal dispersion to lyophilized product. Drug delivery and translational research, 14(11), 3269–3290. https://doi.org/10.1007/s13346-024-01555-4
  8. Patra, P., Katke, S., Singh, S., Panchal, K., Johari, A., Pawar, A. V., Paliwal, R. & Chaurasiya, A. (2024). Development and evaluation of stable long circulating decitabine-loaded copolymeric nanoparticles: harnessing QBD approach and lyophilization technique. Journal of Pharmaceutical Innovation, 19(3). https://doi.org/10.1007/s12247-024-09836-8
  9. Shinde, A., Panchal, K., Patra, P., Singh, S., Enakolla, S., Paliwal, R., & Chaurasiya, A. (2024). QbD Enabled Development and Evaluation of Pazopanib Loaded Nanoliposomes for PDAC Treatment. AAPS PharmSciTech, 25(5), 97. https://doi.org/10.1208/s12249-024-02806-w
  10. Nessa, S., Lavanya, S., Routray, R. K., Chaurasiya, A., Kulkarni, O. P., & Begum, A. S. (2024). Anti-rheumatoid arthritis potential of Halodule pinifolia: development, characterization and in vivo evaluation of H. pinifolia-based oral suspension and lipid nano-emulsion. Inflammopharmacology, 32(2), 1203–1223. https://doi.org/10.1007/s10787-024-01431-0
  11. Rani, S., Sahoo, R. K., Mahale, A., Panchal, K., Chaurasiya, A., Kulkarni, O., Kuche, K., Jain, S., Nakhate, K. T., Ajazuddin, & Gupta, U. (2023). Sialic Acid Engineered Prodrug Nanoparticles for Codelivery of Bortezomib and Selenium in Tumor Bearing Mice. Bioconjugate chemistry, 34(9), 1528–1552. https://doi.org/10.1021/acs.bioconjchem.3c00210
  12. Pardhi, E., Yadav, R., Chaurasiya, A., Madan, J., Guru, S. K., Singh, S. B., & Mehra, N. K. (2023). Multifunctional targetable liposomal drug delivery system in the management of leukemia: Potential, opportunities, and emerging strategies. Life sciences, 325, 121771. https://doi.org/10.1016/j.lfs.2023.121771
  13. Gupta, T., Sahoo, R. K., Singh, H., Katke, S., Chaurasiya, A., & Gupta, U. (2023). Lipid-Based Nanocarriers in the Treatment of Glioblastoma Multiforme (GBM): Challenges and Opportunities. AAPS PharmSciTech, 24(4), 102. https://doi.org/10.1208/s12249-023-02555-2
  14. Panchal, K., Katke, S., Dash, S. K., Gaur, A., Shinde, A., Saha, N., Mehra, N. K., & Chaurasiya, A. (2023). An expanding horizon of complex injectable products: development and regulatory considerations. Drug delivery and translational research, 13(2), 433–472. https://doi.org/10.1007/s13346-022-01223-5
  15. Kumar, R. M., Kumar, H., Bhatt, T., Jain, R., Panchal, K., Chaurasiya, A., & Jain, V. (2023). Fisetin in Cancer: Attributes, Developmental Aspects, and Nanotherapeutics. Pharmaceuticals (Basel, Switzerland), 16(2), 196. https://doi.org/10.3390/ph16020196
  16. Rani, S., Sahoo, R. K., Kumar, V., Chaurasiya, A., Kulkarni, O., Mahale, A., Katke, S., Kuche, K., Yadav, V., Jain, S., Nakhate, K. T., Ajazuddin, & Gupta, U. (2023). N-2-Hydroxypropylmethacrylamide-Polycaprolactone Polymeric Micelles in Co-delivery of Proteasome Inhibitor and Polyphenol: Exploration of Synergism or Antagonism. Molecular pharmaceutics, 20(1), 524–544. https://doi.org/10.1021/acs.molpharmaceut.2c00752
  17. Priya, S., Batra, U., R N, S., Sharma, S., Chaurasiya, A., & Singhvi, G. (2022). Polysaccharide-based nanofibers for pharmaceutical and biomedical applications: A review. International journal of biological macromolecules, 218, 209–224. https://doi.org/10.1016/j.ijbiomac.2022.07.118
  18. Shinde, A., Panchal, K., Katke, S., Paliwal, R., & Chaurasiya, A. (2022). Tyrosine kinase inhibitors as next generation oncological therapeutics: Current strategies, limitations and future perspectives. Therapie, 77(4), 425–443. https://doi.org/10.1016/j.therap.2021.10.010
  19. Chaurasiya, A., Gorajiya, A., Panchal, K., Katke, S., & Singh, A. K. (2022). A review on multivesicular liposomes for pharmaceutical applications: preparation, characterization, and translational challenges. Drug delivery and translational research, 12(7), 1569–1587. https://doi.org/10.1007/s13346-021-01060-y
  20. Paliwal, R., Kumar, P., Chaurasiya, A., Kenwat, R., Katke, S., & Paliwal, S. R. (2022). Development of Nanomedicines and Nano-Similars: Recent Advances in Regulatory Landscape. Current pharmaceutical design, 28(2), 165–177. https://doi.org/10.2174/1381612827666211115170001
  21. Panchal, K., Sahoo, R. K., Gupta, U., & Chaurasiya, A. (2021). Role of targeted immunotherapy for pancreatic ductal adenocarcinoma (PDAC) treatment: An overview. International immunopharmacology, 95, 107508. https://doi.org/10.1016/j.intimp.2021.107508

Before joining BITS Pilani

  1. Singh, A., Chaurasiya, A., Warsi, M. H., Chaurasiya, M., Jain, G. K., Asati, D., Khar, R. K., & Mukherjee, R. (2012). Oral pharmacokinetic study of exemestane SMEDDS and suspension in rat plasma by liquid chromatography-mass spectrometric analysis. Journal of Liquid Chromatography & Related Technologies, 35(15), 2162–2174. https://doi.org/10.1080/10826076.2011.629388
  2. Chaurasiya, A., Singh, A. K., Upadhyay, S. C., Asati, D., Ahmad, F. J., Mukherjee, R., & Khar, R. K. (2012). Lipidic Nanocarrier for oral bioavailability Enhancement of an anticancer agent: Formulation design and evaluation. Advanced Science Letters, 11(1), 43–52. https://doi.org/10.1166/asl.2012.2170
  3. Maheshwari, C., Pandey, R. S., Chaurasiya, A., Kumar, A., Selvam, D. T., Prasad, G. B., & Dixit, V. K. (2011). Non-ionic surfactant vesicles mediated transcutaneous immunization against hepatitis B. International immunopharmacology, 11(10), 1516–1522. https://doi.org/10.1016/j.intimp.2011.05.007
  4. Warsi, M. H., Chaurasiya, A., Jain, G. K., Pathan, S. A., Chander, P., Singh, A. K., Talegaonkar, S., Ahmad, F. J. & Khar, R. K. (2011). Aqueous humor Pharmacokinetics of dorzolamide loaded PLGAChitosan nanoparticles by ultra performance liquid chromatography. Current Pharmaceutical Analysis, 7(3), 189–194. https://doi.org/10.2174/157341211796353200
  5. Singh, A. K., Chaurasiya, A., Awasthi, A., Mishra, G., Asati, D., Khar, R. K., & Mukherjee, R. (2009). Oral bioavailability enhancement of exemestane from self-microemulsifying drug delivery system (SMEDDS). AAPS PharmSciTech, 10(3), 906–916. https://doi.org/10.1208/s12249-009-9281-7
  6. Singh, A. K., Chaurasiya, A., Jain, G. K., Awasthi, A., Asati, D., Mishra, G., Khar, R. K., & Mukherjee, R. (2009). High performance liquid chromatography method for the pharmacokinetic study of bicalutamide SMEDDS and suspension formulations after oral administration to rats. Talanta, 78(4-5), 1310–1314. https://doi.org/10.1016/j.talanta.2009.01.058
  7. Singh, A. K., Chaurasiya, A., Singh, M., Upadhyay, S. C., Mukherjee, R., & Khar, R. K. (2008). Exemestane loaded self-microemulsifying drug delivery system (SMEDDS): development and optimization. AAPS PharmSciTech, 9(2), 628–634. https://doi.org/10.1208/s12249-008-9080-6
  8. Jain, S. K., Chaurasiya, A., Gupta, Y., Jain, A., Dagur, P., Joshi, B., & Katoch, V. M. (2008). Development and characterization of 5-FU bearing ferritin appended solid lipid nanoparticles for tumour targeting. Journal of microencapsulation, 25(5), 289–297. https://doi.org/10.1080/02652040701799598

 

 


Book Chapters

  1. Keerti Mishra, Sonia Verma, Pooja Yadav, Amrendra K. Tiwari, J.V.U.S. Chakradhar, Pavan K. Yadav, Akash Chaurasiya & Manish K. Chourasia. Chapter 20 - Methods for preparation of giant liposomes: Conventional methods; modified electro-techniques, Editor(s): Sophia G. Antimisiaris, In Liposomes in Drug Delivery, Academic Press, 2024, Pages 517-538, ISBN 9780443154911. https://doi.org/10.1016/B978-0-443-15491-1.00002-X.
  2. Akash Chaurasiya, Sonali Singh, Kanan Panchal, Rishi Paliwal & Akanksha Malaiya. Chapter 12 - Fundamentals of a targeted drug delivery system, Editor(s): Umesh Gupta, Amit K. Goyal, In Molecular Pharmaceutics and Nano Drug Delivery, Academic Press, 2024, Pages 289-309, ISBN 9780323919241. https://doi.org/10.1016/B978-0-323-91924-1.00007-1.
  3. Akash Chaurasiya, Amruta Gorajiya & Jayabalan Nirmal. Chapter 19 - Stability testing parameters of nanoscaled product development, Editor(s): Neelesh Kumar Mehra, Saurabh Srivastava, Jitender Madan, Pankaj kumar Singh, In Micro and Nano Technologies, Multifunctional Nanocarriers, Elsevier, 2022, Pages 475-500, ISBN 9780323850414. https://doi.org/10.1016/B978-0-323-85041-4.00010-X.
  4. Rishi Paliwal, Akash Chaurasiya, Kanan Panchal, Puja Nayak, Nilosha Parveen & Shivani R. Paliwal. Chapter 3 - Engineering and functionalization of nanomaterials for theranostic applications in infectious diseases, Editor(s): Keerti Jain, Javed Ahmad, In Developments in Microbiology, Nanotheranostics for Treatment and Diagnosis of Infectious Diseases, Academic Press, 2022, Pages 45-71, ISBN 9780323912013. https://doi.org/10.1016/B978-0-323-91201-3.00003-7.
  5. Akash Chaurasiya, Sumeet Katke, Kanan Panchal & Jayabalan Nirmal. Chapter 9 - Biologics for the management of dementia, Editor(s): Umesh Gupta, Prashant Kesharwani, In Nanomedicine-Based Approaches for the Treatment of Dementia, Academic Press, 2023, Pages 193-234, ISBN 9780128243312. https://doi.org/10.1016/B978-0-12-824331-2.00001-7.
  6. Akash Chaurasiya, Parameswar Patra, Pranathi Thathireddy & Amruta Gorajiya. Chapter 6 - PLGA-based Micro- and Nano-particles: From Lab to Market. Editor(s): Neelesh Kumar Mehra, Arvind Gulbake, In Micro- and Nanotechnologies-Based Product Development, CRC-Taylor & Francis, 2021, Pages 83-95, ISBN 9781003043164. https://doi.org/10.1201/9781003043164
  7. Ridahunlang Nongkhlaw, Parameswar Patra, Akash Chaurasiya, Nirmal Jayabalan & Sachin Dubey. Chapter 6 - Biologics: Delivery options and formulation strategies, Editor(s): Ranjita Shegokar, Drug Delivery Aspects, Elsevier, 2020, Pages 115-155, ISBN 9780128212226. https://doi.org/10.1016/B978-0-12-821222-6.00006-3.
  8. Akash Chaurasiya, Sumeet Katke & Kanan Panchal. Chapter 8 - Nanotechnology-based approaches for Cancer Therapeutics”. Editor(s): Rishi Paliwal, Shivani Rai Paliwal, In Nanomedicine, Nanotheranostics and Nanobiotechnology: Fundamentals and Applications, CRC-Taylor and Francis, 2024, ISBN 9781003130055. https://doi.org/10.1201/9781003130055
  9. Farhan Jalees Ahmad & Akash Chaurasiya, Chapter 7 - Pharmaceutical Utility. Editor(s): Roop K Khar, Suresh P. Vyas, Farhan J Ahmad & Gaurav K Jain, In Lachman/Lieberman’s the theory and practice of industrial pharmacy (4th ed.), CBS Publishers & Distributors, 2013, Pages 164-181, ISBN 9788123923062.