Associate Professor Department of Biological Sciences
Homeostatic synaptic plasticity, Ligand-gated ion channels (mainly nicotinic acetylcholine receptors) function in health and neurological disorders, Neuro-nanoscience, Vitamin D3 and Brain health, Vitamin D3 and nicotine addiction
Birla Institute of Technology & Science, Pilani Hyderabad Campus Jawahar Nagar, Kapra Mandal Dist.-Medchal-500 078 Telangana, India
Manjari SKV,SharonMariam Abraham, Omalur Eshwari, Kishore Golla, Priya Jhelum, Shuvadeep Maity, and Pragya Komal#Tremendous fidelity of Vitamin D3 in age-related neurological disorders.(2024) Molecular Neurobiology; # corresponding author; DOI: 10.1007/s12035-024-03989-w
Renu Heir*, Zahra Abbasi*, Pragya Komal, Haider Altimimi, Marie Franquin, Dionysia Moschou, Julien Chambon, and David Stellwagen# Astrocytes are the source of TNF mediating homeostatic synaptic plasticity. (2024) Journal of Neuroscience (accepted).
Manjari SKV,SharonMariam Abraham, Poornima R, Rajnish Kumar Chaturvedi, Shuvadeep Maity, Pragya Komal*;Unprecedented effect of Vitamin D3 on T-cell receptor beta subunit and alpha7 nicotinic acetylcholine receptor expression in a 3-nitropropionic acid induced mouse model of Huntington’s disease. *corresponding author; 15-116-125, (2023), IBRO Neuroscience Reports, https://doi.org/10.1016/j.ibneur.2023.07.001
Julien Chambon, Pragya Komal, Gil M. Lewitus, Gina M. Kemp, Simone Valade, Houaria Adaidi, Noura Al Bistami , and David Stellwagen; Early TNF-dependent regulation of excitatory and inhibitory synapses on striatal direct pathway medium spiny neurons in the YAC128 mouse model of Huntington’s disease; (2023), Journal of Neuroscience, https://doi.org/10.1523/JNEUROSCI.1655-22.2022.
Pragya Komal*, Manjari SKV, Raad Nashmi; (Invited Review); An opinion on the debatable function of brain resident immune protein, T-cell receptor beta subunit in the central nervous system (2022), IBRO Neuroscience Reports,* corresponding author, https://doi.org/10.1016/j.ibneur.2022.09.003
Manjari SKV, Shuvadeep Maity, Poornima R, Suk-Yu Yau, Vaishali K, David Stellwagen andPragya Komal*; Restorative action of Vitamin D3 on motor dysfunction through enhancement of neurotrophins and antioxidant expression in the striatum (2022), Neuroscience, * corresponding author. https://doi.org/10.1016/j.neuroscience.2022.03.039
Maity S, Komal PImpact of ER Stress and ER-Mitochondrial Crosstalk in Huntington’s Disease. , Kumar V, Saxena A, Tungekar A, Chandrasekar V (2022) International Journal of Molecular Sciences. 23(2):780.
Thomas H Lee, Ahadullah, Brian R Christie, Kangguang Lin, Parco Ming-fai Siu, Li Zhang, Tifai Yuen, Pragya Komal, Aimin Xu, Kwok-fai So, Suk-yu Yau (2021) Chronic AdipoRon treatment mimics the effects of physical exercise on restoring hippocampal neuroplasticity in diabetic mice; Molecular Neurobiology.
Anurag Gautam, Pragya Komal, Ram Sevak Singh, Prabhat Gautam, S. K. V. Manjari, R. S. Ningthoujam (2021);Hardcore producer of polyvinyl alcohol as reducer for the formation of gold nanoparticles Journal of molecular Liquid 334 (116112).
Anurag Gautam, Pragya Komal, Prabhat Gautam, Ashutosh Sharma, Neeraj Kumar and Jae Pil Jung Recent Trends in Noble Metal Nanoparticles for Colorimetric Chemical Sensing and Micro-Electronic Packaging Applications(2021) Metals, 11(2), 329.
Anurag Gautam,Pragya Komal and Ram S. Singh, Future demands for high field MRI diagnostic Journal of chemical sciences(2019)131 (89).
Anurag Gautam and Pragya Komal*, Probable ideal size of Ln3+-based upconversion nanoparticles for single and multimodal imaging Co-ordination Chemistry Reviews; *corresponding author; (2018) 393–404 (376).
BEFORE BITS
Renda A, Penty N, Pragya Komal, Nashmi R (2016) Vulnerability to nicotine self-administration in adolescent mice correlates with age-specific expression of α4* nicotinic receptors Neurophrama, 3908(16)30160-5, Impact factor- 5
Pragya Komal, Nashmi R (2015) T-cell receptors modify neuronal function in the central nervous system Biochem Pharmacol. 97, 512–517 Impact factor - 5.009.
Pragya Komal, Estakhr J, Kamran M, Renda A, Nashmi R (2015) cAMP-dependent protein kinase inhibits α7 nicotinic receptor activity in layer 1 cortical interneurons through activation of D1/D5 dopamine receptors J Physiol593.16, 3513–3532 Impact factor - 5.182.
Pragya Komal, Gudavicius G, Nelson CJ, Nashmi R (2014) T cell receptor activation decreases excitability of cortical interneurons by inhibiting α7 nicotinic receptors. J Neurosci34(1): 22-35 (Featured article) Impact factor - 6.167.
Dau A*, Pragya Komal*, Truong M, Morris G, Evans G, Nashmi R (2013) RIC-3 differentially modulates alpha4beta2 and alpha7 nicotinic receptor assembly, expression, and nicotine-induced receptor upregulation. BMC Neurosci, 3908(16)30160-5, * denotes equal contribution by authors. Impact factor – 3.
Pragya Komal, Evans G, Nashmi R (2011) Rapid agonist application system for fast activation of ligand-gated ion channels. J Neurosci Methods198: 246-254. Impact factor - 2.785.