Ongoing research project details:

Government funding

• DBT Grant: Glucocorticoid receptor (GR)-targeted liposomal nano-platform for drug sensitization, EMT reversal toward effective treatment of aggressive oral cancer (Multi-Institutional Grant: PI, Coordinator: CSIR-IICT)
• DBT Grant: Antibacterial, host-modulating and regenerative nanofibers membrane for guided tissue regeneration (Multi-Institutional Grant: PI, Coordinator: IIT Hyderabad) 
• DST Grant: CRISPR mediated genetic correction of Sickle Cell disease towards clinical trials in a small patient cohort” (Multi-Institutional Grant: as collaborator with CSIR-IICT)

PI of research funding for fellowship

• JRF-Lady Tata Memorial Trust Award:  Investigating the role of GR mediated liposomal delivery system against OSCC and Tumor Microenvironment for targeted therapeutics (PI)
• INSPIRE Fellowship for PhD Scholar: Deciphering the role of SHR-mediated liposomal delivery system in oral cancer and its relation to oral dysbiosis.

Completed research Project:

• Industry Sponsored: EON’s DINI (Diet-Infection-Nutrition-Immunity) Axis approach – Proof of Concept: Immunomodulatory Nutritional Intervention for CRC Management (PI). 

• ICMR-SRF Project: Folate receptor mediated targeting of Oral Cancer: therapeutics and mechanistic investigation of tumor regression (PI).

• In house sponsored project: OC3-Centre for Human Diseases Research (CHDR), Test the efficacy of SHR-mediated drug delivery system for oral cancer. 
• DBT Grant: Transgenic Embryonic stem cell models for studying the role of elevated levels of DNMT1 and DNMT3A in neuropsychiatric disorders funded by DBT, India. (Co-PI) 
• In house sponsored project: Development of personalized DNA markers in breast cancer patients for early diagnosis and prognosis using a non -invasive method. Seed Grant (Co-PI)
• In house sponsored project: Screening of steroid hormone receptors and their ligands for targeted delivery of cationic liposome in cancer cells, Research Initiation Grant. (PI).

 Collaborators:

1. Industrial collaborator: Dr. Anubhab Mukherjee, Principal Scientist, Esperer Onco   Nutrition, Mumbai
2. Dr. Rajkumar Banerjee (CSIR-IICT, Hyderabad)
3. Dr. Madhusudan Rao Gummanur, (ACDS, Secunderabad).
4. Dr. Jyotsnendu Giri, (IIT, Hyderabad)
5. Dr. Venkata Srilakshmi P (NIT, Warangal)

Acknowledgment:

I thank Director, BITS Pilani Hyderabad Campus for providing fund through CHDR. I also thank DBT, DST, ICMR, EON & Lady Tata Memorial Trust for sponsoring research grant/ fellowship. I sincerely thank my collaborators and highly appreciate their support in running our collaborative grants.