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Prof. Nishith Gupta

Professor
Department of Biological Sciences

Integrated Multi-Omics, Mechanobiology, Metabolism & Signaling, Optogenetics, Parasite-Host Interactions
Birla Institute of Technology & Science, Pilani
Hyderabad Campus
Jawahar Nagar, Kapra Mandal
Dist.-Medchal-500 078
Telangana, India

Acknowledgement

Ongoing Projects
  • Physiological and pharmacological significance of formate-nitrite transporters in Toxoplasma gondii: ICMR Research Grant.
  • Lipid and cyclic nucleotide signaling in Toxoplasma gondii: Wellcome Trust – DBT (India Alliance) Senior Fellowship.
  • Optogenetic Illumination of Toxoplasma Lytic Cycle: Indo-Japan Scholar Mobility Program (@Osaka University, Japan).
  • Computational Identification of Therapeutic Targets and AI-based Drug Repurposing in Parasitic Protists: Cross Disciplinary Research Fund by BITS, Pilani (co-PI: Poonam Goyal and Aneesh Chivukula).
  • Sustained Illumination of Natural Environment: BioCyTiH Foundation, India.
  • Proteomics-based identification of host determinants and diagnostic biomarkers of Toxoplasma infection: Indo-German Science & Technology Cooperation (IGSTC) Women in Science, Engineering and Research (WISER) Program with Dr. Ute Distler (University of Mainz, Germany).
  • Optogenetic regulation of parasite signaling: Indo-German Science & Technology Cooperation (IGSTC) Women in Science, Engineering and Research (WISER) Program with Dr. Özlem Günay-Esiyok (Humboldt University of Berlin, Germany).
Previous Grants
  • Biosensor monitoring in Toxoplasma gondii: Indo-Japan Scholar Mobility Program by DST-JSPS (co-PI, Takeharu Nagai @ Osaka University, Japan).
  • Pyruvate homeostasis in Toxoplasma gondii: DST-SERB Core Research Grant.
  • A novel lipid-regulated calcium homeostasis in Toxoplasma gondii. German Research Foundation.
  • Functional and physiological significance of phosphatidylethanolamine biogenesis in Toxoplasma gondii:  German Research Foundation.
  • Cyclic nucleotides-mediated ion homeostasis in the malaria parasite:  German Research Foundation; co-PI: Alexander Maier (ANU).
  • Metabolic basis of obligate intracellular parasitism: German Research Foundation.
  • Optogenetic dissection of cyclic NMP signaling T. gondii: German Research Foundation, co-PI: Peter Hegemann.
  • Cyclic NMP signaling and metabolic regulation in T. gondii: German Research Foundation.
  • Synthesis vs. import of host-derived phospholipids by T. gondii: German Research Foundation; co-PI: Maik Lehmann.
  • Carbon metabolisms of acute and chronic stages of T. gondii: German Research Foundation.
  • Phosphatidylcholine synthesis as a drug target in T. gondii: Young scientist grant from European Society of Infectious Diseases and Microbiology.
  • Biogenesis of inositol-lipids in T. gondii: German Research Foundation, co-PI: Andreas Herrmann (HU, Berlin).
  • Modeling of lipid biogenesis in Toxoplasma-infected human cell: German Research Foundation, co-PIs: Herrmann Holzhütter (Charité, Berlin) and Richard Lucius (HU, Berlin).
  • High-throughput anti-coccidian drug screening using YFP-parasite, Novartis Animal Healthcare, co-PI: Richard Lucius (HU, Berlin).
  • In vivo parasite-host interactions in the Eimeria-mouse model. Manuela Schmid (doctoral student) & Nishith Gupta (host PI), Helmholtz Foundation.
  • Central carbon metabolism of T. gondii. Martin Blume (doctoral student) & Nishith Gupta (host PI), Helmholtz Foundation.