Publications - BITS Pilani

Journal Articles

Mehul P. Parmar, Hrushikesh S. Chaudhari, Disha P. Vala, Pradip M. Macwan, Joaquina Nogales, Subash C. Sahoo, Deepak B. Salunke, Sourav Banerjee, Kondapalli Venkata Gowri Chandra Sekhar, Adam N. Khan, Jose Padron, and Hitendra M. Patel, One-Pot Diastereoselective Synthesis of Spiro[pyrimidine-5,8′-thiazolo[5,4‑f ]quinoline]triones and Diimidazo-pyrazinyl-bis(1,3-dimethyl-2,4,6-trioxohexahydropyrimidine-5-ylium)dihydrate as Anticancer Agents. Journal of Organic Chemistry, 2026, https://doi.org/10.1021/acs.joc.6c00482.
Kosana Sai Chaitanya, Tsz Tin Yu, Hrushikesh Chaudhari,Nidhi Orenkonday, Pranali Vijaykumar Kuthe, Naresh Kumar, Ruchi Jain Dey, Sankaranarayanan Murugesan, Kondapalli Venkata Gowri Chandra Sekhar, Discovery of Triazole-Tethered Glycinate and Propanoate Derivatives Bearing a Thiolactone Moiety as Quorum Sensing Inhibitors of Pseudomonas aeruginosa: Design, Synthesis, Biological Evaluation, and Biofilm Inhibition, RSC Advances, 2026, 16, 27977-27993
Rajkumar Reddyrajulaa, Umadevi Etikyala, Dinesha P, Sampat P V, Shreeganesh Subraya Hedge, Mohammed Muzaffar-Ur-Rehman, Chandra Sekhar Kondapalli Venkata Gowri, Udayakumar Dalimba, Vijjulatha Manga, Development of Potential CDK9 Inhibitors through Pharmacophore-Based Virtual Screening, 3DQSAR, Molecular Docking, MD Simulation, and In Vitro Anticancer Evaluation, Scientific Reports, Article number: (2026)
Gauri Karande, Jatin Malik, Rafael Bala˜na Fouce, Chandra Sekhar Venkata Gowri Kondapalli, Sankaranarayanan Murugesan, Structure-based E-pharmacophore guided in silico repurposing of clinically approved drugs targeting methionyl-tRNA synthetase against leishmaniasis, Journal of Molecular Graphics and Modelling, 2026, 146, 109430.
Pranali Vijaykumar Kuthe, Mohammed Muzaffar-Ur-Rehman, Kondapalli Venkata Gowri Chandra Sekhar, Sankaranarayanan Murugesan, Integrative Homology, AI-Based Modelling of PfSET3 and Virtual Screening of Microbial-Derived Inhibitors as Potential Anti-Malarial Agents, In Silico Pharmacology, 2026, 14, 91.
Kosana Sai Chaitanya, Tsz Tin Yu, Hrushikesh Chaudhari, Ni dhi Orekonday, Naresh Kumar, Ruchi Jain Dey, Sankaranarayanan Murugesan, Kondapalli Venkata Gowri Chandra Sekhar, Design, Synthesis, and Evaluation of Indole-based 1,2,3-Triazoles as Potential Quorum Sensing and Biofilm Inhibitors Against Pseudomonas aeruginosa. Archiv der Pharmazie, 2026, 359, e70209.
Ranita Roy, Adinarayana Nandikolla, Debabrata Ghosh Dastidar, Urmi Chatterji, Kondapalli Venkata Gowri Chandra Sekhar, and Gopal Chakrabarti, Spirochromanone Cst-17 as a Potent Microtubule Destabilizing Agent Showing Anticancer Effects in HeLa Cells by Binding to Tubulin. Future Medicinal Chemistry 2026, 18(6), 619-636.
V.M. Rao Bandaru, Ashna Fathima, Suryansh Sengar, Markus Schweipert, Kosana Sai Chaitanya, Muzaffar-Ur-Rehman Mohammed, Suraj T. Gore, Trinath Jamma, Vivek Sharma, Chandrasekhar Abbineni, Franz-Josef Meyer-Almes, Kondapalli Venkata Gowri Chandra Sekhar, Targeted HDAC8 Inhibition with Non-Hydroxamate [1,2,4]Triazolo[4,3-a] Quinoline Compounds. Scientific Reports 2026, 16, 7472.
Jatin Malik, Estela Melcon-Fernandez, Rafael Balana Fouce, Chandra Sekhar Kondapalli Venkata Gowri, Murugesan Sankaranarayanan, Nitro-thiochromene derivatives as promising anti-leishmanial agents: Synthesis, biological evaluation, and in silico insights. Journal of Molecular Structure, 2026, 1356, 145170.
Mahesh Kumar Talamadla, Shreyash Rajendra Moharir, Mihika Katdare, Suryansh Sengar, Swati, Vivek Sharma, Sankaranarayanan Murugesan, Kondapalli Venkata Gowri Chandra Sekhar, 2-(1H-Pyrazol-1-yl)pyrimidine derivatives as promising anticancer candidates: synthesis, biological studies, and computational insights. Journal of Molecular Structure, 2026, 1356, 145158.
J John Paul, Kosana Sai Chaitanya, R Ganesan, Purushottam Jha, Kondapalli Venkata Gowri Chandra Sekhar, S Sindhu, Zinc Based Organic Metal Complexes for OLED Applications, Synthetic Metals, 2026, 316, 117980.
Boddupalli Venkata Siva Kumar, Puja Bhardwaj, Hrushikesh S. Chaudhari, Ruchi Jain Dey, Sankaranarayanan Murugesan, Kondapalli Venkata Gowri Chandra Sekhar, Design, synthesis, and biological evaluation of (E)-3-amino-N′-substituted benzylidene-6-chloropyrazine-2-carbohydrazide derivatives as anti-mycobacterial agents, Bioorganic Chemistry, 2025, 167, 109206.
Jatin Malik, Gauri Karande, Sankaranarayanan Murugesan, Kondapalli Venkata Gowri Chandra Sekhar, Recent Advances in Triazole Hybrid Molecules for the Therapeutic Management of Neglected Tropical Diseases, RSC Medicinal Chemistry, 2025, 16, 5292 - 5317.
Moharir, Shreyash Rajendra, Mahesh Kumar Talamadla, Puja Bhardwaj, Arnab Banerjee, Ruchi Jain Dey, and Kondapalli Venkata Gowri Chandra Sekhar. Harnessing SIRT1 activators for effective PCOS treatment: A new frontier.Biomedicine & Pharmacotherapy 190 (2025): 118361.
Santhosh, C. R., Sampath Chinnam, Hrushikesh S. Chaudhari, Kondapalli Venkata Gowri Chandra Sekhar, Gbolahan O. Oduselu, Vishal Ahuja, Kumarappan Chidambaram, Nagaraju Kerru, and G. M. Madhu. Eco-friendly polyethylene glycol (PEG-400): PEG mediated synthesis, in-vitro, molecular dynamics, DFT, docking, ADMET and MM-GBSA studies of novel sulfonamides as potential antioxidant agents.Journal of Molecular Structure (2025): 143201.
Kumar, Boddupalli Venkata Siva, Mahesh Kumar Talamadla, Adinarayana Nandikolla, Yogesh Mahadu Khetmalis, Gauri Shetye, Scott G. Franzblau, Sankaranarayanan Murugesan, and Kondapalli Venkata Gowri Chandra Sekhar. Exploration of quinoxaline triazoles as antimycobacterial agents: design, synthesis and biological evaluation.Bioorganic & Medicinal Chemistry Letters 121 (2025): 130177.
Ala, Chandu, Sivaprakash Ramalingam, Chandra Sekhar Kondapalli Venkata Gowri, and Murugesan Sankaranarayanan. A critique review of fetal hemoglobin modulators through targeting epigenetic regulators for the treatment of sickle cell disease. Life Sciences 369 (2025): 123536.
NVM Rao Bandaru, Ashna Fathima, Vandana Joshi, Markus Schweipert, Obanna Pathur, Kosana Sai Chaitanya, Trinath Jamma, Vivek Sharma, Chandrasekhar Abbineni, Franz-Josef Meyer-Almes, and Kondapalli Venkata Gowri Chandra Sekhar. Design, synthesis, and biological evaluation of substituted benzyl-triazolopyridine derivatives as non-hydroxamate based HDAC8 inhibitors. European Journal of Medicinal Chemistry Reports 13 (2025): 100255.
Talamadla, Mahesh Kumar, Adinarayana Nandikolla, Singarapalle Shobha, Pranav Pramod Nayar, Muthyala Murali Krishna Kumar, Murugesan Sankaranarayanan, and Kondapalli Venkata Gowri Chandra Sekhar. Exploring the Anti‐Tubercular Potential of 2‐(1H‐Pyrazol‐1‐yl) Pyrimidine: Design, Synthesis, Biological Evaluation and Molecular Docking Studies. Chemistry & Biodiversity (2025): e202500321.
Nakka, Srinuvasu, Suryansh Sengar, Kosana Sai Chaitanya, Swati, Ala Chandu, Murugesan Sankaranarayanan, Vivek Sharma, Nagaraju Devunuri, and Kondapalli Venkata Gowri Chandra Sekhar. Design and Synthesis of Novel Spiro [Chromane‐2, 4′‐Piperidin]‐4‐One Derivatives: Anti‐Proliferative Investigation and Molecular Docking Studies.Asian Journal of Organic Chemistry 14, no. 2 (2025): e202400604.
Nakka, Srinuvasu, Kosana Sai Chaitanya, Suryansh Sengar, Ala Chandu, Murugesan Sankaranarayanan, Vivek Sharma, Nagaraju Devunuri, and Kondapalli Venkata Gowri Chandra Sekhar. Exploring 4-morpholinopyrrolo-[2, 3-d]-pyrimidine derivatives as novel anti-cancer agents: Design, synthesis and biological studies. Journal of Molecular Structure 1319 (2025): 139565.
Kumar, Boddupalli Venkata Siva, Yogesh Mahadu Khetmalis, Kosana Sai Chaitanya, Ala Chandu, Gauri Shetye, Rui Ma, Sankaranarayanan Murugesan, Scott G. Franzblau, and Kondapalli Venkata Gowri Chandra Sekhar. Design, synthesis and biological evaluation of novel pyrido-[2, 3-d]-pyrimidin-2-amine analogues as antimycobacterial agents.Journal of Molecular Structure 1303 (2024): 137600.
Sai Chaitanya, Kosana, Pooja Gupta, Surendar Chitti, Yogesh Mahadu Khetmalis, Ala Chandu, Sankaranarayanan Murugesan, Mukesh Pasupuleti, and Kondapalli Venkata Gowri Chandra Sekhar. Development and Biological Evaluation of Novel Spiro 4‐Chromanones as Potent Quorum Sensing Inhibitors. Journal of Chemistry 2024, no. 1 (2024): 8227205.
Yogesh Mahadu Khetmalis, Singarapalle Shobha, Adinarayana Nandikolla, Ala Chandu, Sankaranarayanan Murugesan, Muthyala Murali Krishna Kumar and Kondapalli Venkata Gowri Chandra Sekhar*, Design, synthesis, and anti-mycobacterial evaluation of 1,8-naphthyridine-3-carbonitrile analogues. RSC Advances, 2024, 14, 22676.
Solai Murugappan, Pranali Vijaykumar Kuthe, Kondapalli Venkata Gowri Chandra Sekhar and Murugesan Sankaranarayanan, Recent developments in thiochromene chemistry. Organic and Biomolecular Chemistry. DOI: 10.1039/d4ob00690a.
Chandu Ala, Renuka Parshuram Josh, Pragya Gupta, Sangam Giri Goswami, Sivaprakash Ramalingam, Kondapalli Venkata Gowri Chandra Sekhar, Murugesan Sankaranarayanan. A critical review of therapeutic interventions in sickle cell disease: Progress and challenges. Archiv Der Pharmazie, 2024; e2400381.
Nakka, S., Raza, A., Chaitanya, K. S., Bandaru, N. V. M. R., Chandu, A., Murugesan, S., Nagaraju D, Sharma, A K. & Kondapalli Venkata Gowri Chandra Sekhar*. Design, synthesis, and biological evaluation of novel quinoxaline aryl ethers as anticancer agents. Chemical Biology & Drug Design, 2024, 103 (3), e14502.
Kumar, B. V. S., Khetmalis, Y. M., Chaitanya, K. S., Chandu, A., Shetye, G., Ma, R., Murugesan,, Franzblau, S. G., & Kondapalli Venkata Gowri Chandra Sekhar*. Design, synthesis and biological evaluation of novel pyrido-[2,3-d]-pyrimidin-2-amine analogues as antimycobacterial agents. Journal of Molecular Structure, 2024, 1303, 137600.
Yogesh Mahadu Khetmalis, Guruvelli Padma Vijaya Sangeetha,Ala Chandu,Swati,Sankaranarayanan Murugesan,Vivek Sharma,Muthyala Murali Krishna Kumar, Kondapalli Venkata Gowri Chandra Sekhar*, Design, Synthesis, and Biological Evaluation of Novel Oxindole Analogs as Anti-Tubercular Agents. Future Medicinal Chemistry 2023, 15 (5), 1323-1342.
Adinarayana Nandikolla, Yogesh Mahadu Khetmalis, Boddupalli Venkata Siva kumar, Ala Chandu, Banoth Karan Kumar, Gauri Shetye, Rui Ma, Sankaranarayanan Murugesan, Scott G. Franzblau, Kondapalli Venkata Gowri Chandra Sekhar*, Design, Synthesis and Biological Evaluation of Phenanthridine Amide and 1,2,3-Triazole Analogues against Mycobacterium tuberculosis. RSC Medicinal Chemistry, 2023, 14, 1549-1561.
Adinarayana Nandikolla, Yogesh Mahadu Khetmalis, Guruvelli Padma Vijaya Sangeetha, Ala Chandu, Swati, Muthyala Murali Krishna Kumar, Vivek Sharma, Sankaranarayanan Murugesan, and Kondapalli Venkata Gowri Chandra Sekhar*, Tetrahydroisoquinoline based 5-Nitro-2-furoic acid Derivatives: A Promising New Approach for Anti-Tubercular Agents, New Journal of Chemistry, 2023, 47, 15378-15389.
Yogesh Mahadu Khetmalis, Ashna Fathima, Markus Schweipert, Cécile Debarnot, Naga Venkata Madhusudhan Rao Bandaru, Sankaranarayanan Murugesan, Trinath Jamma, Franz-Josef Meyer-Almes and Kondapalli Venkata Gowri Chandra Sekhar*, Design, Synthesis, and Biological Evaluation of Novel Quinazolin-4(3H)-One-Based Histone Deacetylase 6 (HDAC6) Inhibitors for Anticancer Activity, International Journal of Molecular Sciences 2023, 24 (13), 11044.
Abirami, Banoth Karan Kumar, Faheem, Sanchita Dey, Samridhi Johri, Rosa M. Reguera, Rafael Bala˜na-Fouce, Kondapalli Venkata Gowri Chandra Sekhar, Murugesan Sankaranarayanan, Molecular-level strategic goals and repressors in Leishmaniasis – Integrated data to accelerate target-based heterocyclic scaffolds, European Journal of Medicinal Chemistry, 2023, 257, 115471.
Savita, Adinarayana Nandikolla, Adarash Kumar Shukla, Kondapalli Venkata Gowri Chandra Sekhar and Anupam Bhattacharya, Visible light sensing of ions by a cynoquinoxaline 1,4-dioxide-based probe and its applications. Dalton Transactions, 2023, 52, 4103.
Yogesh Mahadu Khetmalis, Bakhya Shree, Boddupalli Venkata Siva Kumar, Markus Schweipert, Cécile Debarnot, Fathima Ashna, Murugesan Sankaranarayanan, Jamma Trinath, Vivek Sharma, Franz-Josef Meyer-Almes, Kondapalli Venkata Gowri Chandra Sekhar*, Design, synthesis, and biological evaluation of tetrahydroisoquinoline based hydroxamate derivatives as HDAC 6 inhibitors for cancer therapy. Journal of Molecular Structure, 2023, 1278, 134952.
Bodupalli Venkata Siva Kumar, Yogesh Mahadu Khetmalis, Adinarayana Nandikolla, Banoth Karan Kumar, Kevin Van Calster, Sankaranarayanan Murugesan, Davie Cappoen, and Kondapalli Venkata Gowri Chandra Sekhar*, Design, Synthesis, and Antimycobacterial Evaluation of Novel Tetrahydroisoquinoline Hydrazide Analogs, Chemistry & Biodiversity 2023, 20, e202200939.
Samridhi Johri, Banoth Karan Kumar, Sanchita Dey, Faheem, Rafael Balana-Fouce, Kondapalli Venkata Gowri Chandra Sekhar*, Selvaraj Kunjiappan, Sankaranarayanan Murugesan, Inspection of in-house designed novel thiochromone amino-acid conjugate derivatives as Lm-NMT inhibitor – An in-silico analysis. Journal of Molecular Graphics and Modelling 2023, 119, 108397.
Snehal Rajkumar Jadhav, Banoth Karan Kumar, Renuka Parshuram Joshi, Chougule Kishor Suryakant, Ala Chandu, Mohammed Muzaffar-Ur-Rehman, Yogesh Mahadu Khetmalis, Adinarayana Nandikolla, Sankaranarayan Murugesan and Kondapalli Venkata Gowri Chandra Sekhar*, Retrospective Review of Chromane Analogues as Anti-Protozoal Leads: A Decade's Worth of Evolution. Current Topics in Medicinal Chemistry, 2023, 23 (9), 713-735.
Ravi Kiran Panchakarla, Punna Rao Ravi, Manidhar Syam Kumar Buddha, Sumanth Mullangi, and Kondapalli Venkata Gowri Chandra Sekhar*, In silico toxicity assessment and trace level quantification of two genotoxic impurities in silodosin using capillary gas chromatography, Journal of Analytical Science and Technology, 2023 (https://doi.org/10.1186/s40543-023-00378-1).
Surendar Chitti, Adinarayana Nandikolla, Yogesh Mahadu Khetmalis, Kevin Van Calster, Boddupalli Venkata Siva Kumar, Banoth Karan Kumar, Sankaranarayanan Murugesan, Davie Cappoen, and Kondapalli Venkata Gowri Chandra Sekhar *, Design, Synthesis and Biological Evaluation of Novel Spiro-[chroman-2,4'-piperidin]-4-one Analogues as Anti-Tubercular Agents. Chemistry & Biodiversity 2022,
Surendar Chitti, Kevin Van Calster, Davie Cappoen, Adinarayana Nandikolla, Yogesh Mahadu Khetmalis, Paul Cos, Banoth Karan Kumar, Sankaranarayanan Murugesan and Kondapalli Venkata Gowri Chandra Sekhar* Design, synthesis and biological evaluation of benzo-[d]-imidazo-[2,1-b]-thiazole and imidazo-[2,1-b]-thiazole carboxamide triazole derivatives as antimycobacterial agents. RSC Advances 2022, 12, 22385–22401.
Adinarayana Nandikolla, Yogesh Mahadu Khetmalis, Kalaga Mahalakshmi Naidu, Banoth Karan Kumar, Sankaranarayanan Murugesan, Kondapalli Venkata Gowri Chandra Sekhar*, “Discovery of potent antitubercular agents: Design, synthesis and biological evaluation of 4-(3-(4-substitutedpiperazin-1-yl) -quinoxalin-2-yl)- naphthalen-1-ol analogues.” Toxicology in Vitro 2022, 82, 105370.
Adinarayana Nandikolla, Srinivasarao Singireddi, Karan Kumar Banoth, Sankaranarayanan Murugesan, Himanshu Aggarwal, Rafael Balana-Fouce, Melcon-Fernandez Estela, Kondapalli Venkata Gowri Chandra Sekhar*, “Design, synthesis and evaluation of novel phenanthridine triazole analogs as potential antileishmanial agents.” Future Medicinal Chemistry 2022, 14 (12), 867-880.
Faheem, Sanchita, D., Samridhi, J., M. Abirami, Karan Kumar, B., Donatella, T., Nicoletta, B., Rafael B. F., Chandra Sekhar, K.V.G., Murugesan, S., Search for structurally diverse heterocyclic analogs as dual-acting antimalarial and antileishmanial agents: An overview. European Journal of Medicinal Chemistry 2022, 4, 100031
Yogesh, M, K., Surendar, C., Anjani, U. W., Karan Kumar, B., Murali Krishna Kumar M., Murugesan, S., Chandra Sekhar, K.V.G.,*Design, Synthesis and Anti-mycobacterial Evaluation of Imidazo-[1,2-a]-pyridine Analogues. RSC Medicinal Chemistry. 2022, 13, 327-342.
Surendar, C., Sravani, P., Adinarayana, N., Tarun Kumar, P., Karan Kumar, B., Murugesan, S., Balaram, G., Chandra Sekhar, K.V.G.*Design, Synthesis and SAR Studies of Novel Spirochromanone hydrochloride Analogues as Anticancer Agents. Future Medicinal Chemistry, 2022, 22 (5), 325-342.
Archana, B., N.V.M. Rao, B., Raghurami Reddy, B., Suraj, T.G., Subhendu, M., Wesley Roy, B., Sumanth Kumar V., Krishna Satya Alapati, Chandra Sekhar, K.V.G., Kavitha, N., Chandrasekhar, A., Susanta, Design, synthesis, and biological evaluation of phenyl thiazole-based AR-V7 degraders. Bioorganic & Medicinal Chemistry Letters, 2022, 55, 128448.
Karan Kumar, B., Faheem., Rafael B. F., Estela M. F., Yolanda, Rosa M. R., Adinarayana, N., Chandra Sekhar, K.V.G., Satheesh Varma, V., Murugesan, S.Design, synthesis and evaluation of novel β-carboline ester analogues as potential anti-leishmanial agents. Journal of Biomolecular Structure and Dynamics 2022, 40 (23), 12592-12607.
Karan Kumar, B., Faheem,Chandra Sekhar, K.V.G. Rupal O., Vijay Kumar P., Aravinda Pai, Murugesan, S., Pharmacophore based virtual screening, molecular docking, molecular dynamics and MMGBSA approach for identification of prospective SARS-CoV-2 inhibitor from natural product databases. Journal of Biomolecular Structure and Dynamics, 2022, 40(3), 1363-1386.
Nandikolla, A., Srinivasarao, S., Kumar, B.K., Murugesan, S., Aggarwal, H., Balaña-Fouce, R., Melcón-Fernandez, E., Pérez-Pertejo, Y., Chandra Sekhar, K.V.G. * Novel phenanthridine amide analogs as potential anti-leishmanial agents: In vitro and in silico insights. Bioorganic Chemistry, 2021, 117, 105414.
, Karan Kumar, B., Chandra Sekhar, K.V.G., Subhash Chander, Selvaraj, K., Murugesan, S. 1,2,3,4-Tetrahydroisoquinoline (THIQ) as privileged scaffold for anticancer de novo drug design. Expert Opinion in Drug Discovery, 2021, 16(10), 1119-114.
Ravi Kiran P., Punna Rao, R., Chandra Sekhar, K.V.G. * Liquid chromatography‑tandem mass spectrometric method for trace quantification of ethyl methanesulfonate: a genotoxic impurity in dapoxetine hydrochloride. Future Journal of Pharmaceutical Sciences, 2021, 7, 191.
Shivani, M., Adinarayana, N., Murugesan, S., Chandra Sekhar, K.V.G.*1,8-Naphthyridine derivatives: an updated review on recent advancements of their myriad biological activities. Future Medicinal Chemistry, 2021, 13(18), 1591-1618.
Yogesh, M, K., Shivani, M., Murugesan, S., Chandra Sekhar, K.V.G.* Oxindole and its derivatives: A review on recent progress in biological activities. Biomedicine & Pharmacotherapy 2021, 141, 111842.
Surendar, C., Sravani, P., Adinarayana, N., Tarun Kumar, P., Karan Kumar, B., Murugesan, S., Balaram, G., Chandra Sekhar, K.V.G.*Design, synthesis and biological evaluation of 7–(5–((substituted – amino)-methyl)-thiophen–2–yl)-spiro-[chroman–2,4′–piperidin]–4–one hydrochloride analogues as anticancer agents. Bioorganic Chemistry, 2021, 112, 104865.
Adinarayana, N., Srinivasarao, S., Yogesh, M.K., Karan Kumar, B., Murugesan, S., Gauri, S., Rui M., Scott, G. F., Chandra Sekhar, K.V.G.*Design, synthesis and biological evaluation of novel 1,2,3-triazole analogues of Imidazo-[1,2-a]-pyridine-3-carboxamide against Mycobacterium tuberculosis. Toxicology In Vitro, 2021, 74, 105137.
Faheem, Karan Kumar, B., Chandra Sekhar, K.V.G,Subhash, C., Selvaraj K, Murugesan, S.Medicinal chemistry perspectives of 1,2,3,4-tetrahydroisoquinoline analogs – biological activities and SAR studies. RSC Advances, 2021, 11, 12254–12287.
Ravi Kiran P, Punna Rao R, Chandra Sekhar, K.V.G.*Selective and Sensitive UHPLC Method for the Trace Analysis of Formaldehyde in Drug Substance Using Fused-core Column Technology and Detailed Pre-column Derivatization study. Current Pharmaceutical Analysis, 2021, 17, 201-209.
Faheem, Karan Kumar, B., Chandra Sekhar, K.V.G,Selvaraj K, Joazaizulfazli J, Rafael B, Murugesan, S. Recent update on the anti-infective potential of β-carboline analogs. Mini-Reviews in Medicinal Chemistry 2021, 21, 398 – 425.
Adinarayana, N., Srinivasarao, S., Karan Kumar, B., Murugesan, S., Himanshu A., Louise, L.M., Terry, K.S., Chandra Sekhar, K.V.G.*Synthesis, study of antileishmanial and antitrypanosomal activity of imidazo pyridine fused triazole analogues. RSC Advances, 2020, 10, 38328-38343.
Suresh, A., Srinivasarao, S., Yogesh, M. K., Shashidhar, N., Murugesan, S., Chandra Sekhar, K.V.G.*Inhibitors of pantothenate synthetase of Mycobacterium tuberculosis – a medicinal chemist perspective. RSC Advances, 2020, 10, 37098-37115.
Faheem, Karan Kumar, B., Chandra Sekhar, K.V.G., Selvaraj, K., Joazaizulfazli, J., Rafael, B. F., Babu, L.T., Murugesan, S. Druggable targets of SARS-CoV-2 and treatment opportunities for COVID-19. Bioorganic Chemistry,2020, 104, 104269.
Karan Kumar, B., Faheem, Chandra Sekhar, K.V.G,Adinarayana, N., Murugesan, S. Recent evolution on synthesis strategies and anti-leishmanial activity of β-carboline derivatives – An update. Heliyon, 2020, 6, e04916.
Srinivasarao, S., Adinarayana, N., Suresh, A., Agnieszka, E., Agnieszka, G.,Balaram, G., Karankumar, B., Murugesan, S., Sravani, P., Himanshu A., Chandra Sekhar, K.V.G.* Discovery of 1,2,3-triazole based quinoxaline-1,4-di-N-oxide derivatives as potential anti-tubercular agents. Bioorganic Chemistry, 2020, 100, 103955.
Srinivasarao, S., Adinarayana, N., Suresh, A., Kevin Van C, Linda De V, Davie C.,Balaram, G., Himanshu A., Murugesan, S., Chandra Sekhar, K.V.G.* Seeking potent anti-tubercular agents: design and synthesis of substituted-N-(6-(4-(pyrazine-2-carbonyl)piperazine/homopiperazine-1-yl)pyridin-3-yl)benzamide derivatives as anti-tubercular agents. RSC Advances, 2020, 10, 12272-12288.
Srinivasarao, S., Adinarayana, N., Shashidhar, N., Tsz, T.Y., Sravani, P., Balaram, G., Murugesan, S., Naresh, K., Chandra Sekhar, K.V.G.*Design, synthesis and biological evaluation of 1,2,3-triazole based 2-aminobenzimidazoles as novel inhibitors of LasR dependent Quorum Sensing in Pseudomonas aeruginosa. RSC Advances, 2019, 9, 29273-29292.
Surendar, C., Srinivasarao, S., Santosh, P.K.R., Prakruti, T., Yamini, B., Chandan, K., Krishnan, R., Balaram, G., Chandra Sekhar, K.V.G.*Design, synthesis and biological evaluation of 2-(3,4-dimethoxyphenyl)-6-(1,2,3,6-tetrahydropyridin-4-yl)imidazo[1,2-a]pyridine analogues as antiproliferative agents. Bioorganic & Medicinal Chemistry Letters, 2019, 29, 2551-2558.
Suresh, N., Surendar, C., Suresh, A., Sridhar, G., Mallika, A., Debanjan, B., Nishant, J., Chandra Sekhar, K.V.G.*Design, Synthesis, and Biological Evaluation of 2-(4-Aminophenyl) benzothiazole Analogues as Antiproliferative Agents, Journal of Heterocyclic Chemistry, 2019, 56, 520-532.
Arun kumar, T., Ratnakaram V. N., Srinivasu, N., Yamini, B., Balaram, G., Chandra Sekhar, K.V.G.* Design, synthesis and anti-tumour activity of new pyrimidine-pyrrole appended triazoles. Toxicology In Vitro, 2019, 60, 87–96.
Mahalakshmi Naidu, K., Rudresh Naik, G., Chandra Sekhar, K.V.G.*Design, synthesis and biological evaluation of 5-(2-(4-(substitutedbenzo[d]isoxazol-3-yl)piperazin-1-yl)acetyl)indolin-2-one and 5-(2-(4-substituted piperazin-1-yl)acetyl)indolin-2-one analogues as novel anti-tubercular agents. Arabian Journal of Chemistry, 2019, 12, 2418-2429.
Nagesh, H.N., Srinivasarao, S., Suresh, A., Nizalapur, S., Murugesan, S., Kanneboina, K., Kumar, N., Chandra Sekhar, K.V.G.*Sulfur-Assisted Deprotection of Methylene Nitrile Group: One-Pot Synthesis of 4-Substituted-2H-1,2,3-triazoles Chemistry Select, 2018, 3, 7565-7571.
Chander, S., Ashok, P., Reguera, R., Perez, M., Andres, R., Rafael, B., Chandra Sekhar, K.V.G.* Murugesan, S. Synthesis and activity of benzopiperidine, benzopyridine and phenyl piperazine based compounds against Leishmania infantum. Experimental Parasitology, 2018, 189, 49-60.
Srinivasarao, S., Nizalapur, S., Yu T T., Wenholz, D.S., Trivedi, P., Ghosh, B., Rangan, K., Kumar, N., Chandra Sekhar, K.V.G.*Design, Synthesis and Biological Evaluation of Triazole-Containing 2-Phenylindole and Salicylic Acid as Quorum Sensing Inhibitors against Pseudomonas aeruginosa, Chemistry Select, 2018, 3, 9170-9180.
Suresh N., Suresh A., Suresh Y., Manikapal, B., Mallika, A., Chandra Sekhar, K.V.G.*Anti-proliferative activity, molecular modeling studies and interaction with calf thymus DNA of novel ciprofloxacin analogues. Journal of Chemical Sciences 2018, 130, 121.
Suresh, A., Srinivasarao, S., Agnieszka, Ewa, Mallika, A., Lherbet, C, ChandraSekhar, K.V.G.* Design, synthesis of 9H-fluorenone based 1,2,3-triazole analogues as Mycobacterium tuberculosis InhA inhibitors. Chemical Biology & Drug Design 2017, 91, 1078-1086.
Suresh, N, Chitti S, Suresh, A, Bhattacharjee D, Rao BB, Jain N, Alvala M, Chandra Sekhar, K.V.G.*Design and synthesis of 4-morpholino-6-(1,2,3,6-tetrahydropyridin-4-yl)-N-(3,4,5-trimethoxyphenyl)-1,3,5-triazin-2-amine analogues as tubulin polymerization inhibitors. Bioorganic & Medicinal Chemistry Letters, 2017, 27, 3794-3801.
Lindemann, M., Deuther-Conrad, W., Moldovan, R., Brust, P., Wenzel, B., Chandra Sekhar, K.V.G. Do spiroindolines have the potential to replace vesamicol as lead compound for the development of radioligands targeting the vesicular acetylcholine transporter? Bioorganic & Medicinal Chemistry, 2017,25, 5107-5113.
Suresh, A., Mahalakshmi Naidu K., Srinivasarao, S., Agnieszka,N., Ewa, AK., Misra, S., Murugesan, S., Chander, S., Krishnan, R., Chandra Sekhar, K.V.G.* Identification and development of pyrazolo[4,3-c]-pyridine carboxamides as Mycobacterium tuberculosis pantothenate synthetase inhibitors. New Journal of Chemistry, 2017, 41, 347-357.
Mahalakshmi Naidu K., Srinivasarao, S., Agnieszka,N., Ewa, A-K., Chandra Sekhar, K.V.G. *Seeking potent anti-tubercular agents: Design, synthesis, anti-tubercular activity and docking study of various ((triazoles/indole)-piperazin-1-yl/1,4-diazepan-1-yl)benzo[d]isoxazole derivatives. Bioorganic & Medicinal Chemistry Letters, 2016, 26, 2245-2250.
Suresh, N., Surendar, C., Bhaskara Rao, B., Mallika, A., Nishant J., Chandra Sekhar, K. V. G.* Synthesis and biological evaluation of pyrrolo[2,3-b]pyridine analogues as antiproliferative agents and their interaction with calf thymus DNA.European Journal of Medicinal Chemistry, 2016, 114, 220-231.
Suresh, A., Suresh, N., Misra, S., Krishna Kumar, M.M., Chandra Sekhar, K.V.G.*Design, Synthesis and Biological Evaluation of New Substituted Sulfonamide Tetrazole Derivatives as Antitubercular Agents. Chemistry Select, 2016, 1, 1705-1710.
Nagesh, H.N., Suresh, A., Reddy, M.N., Suresh, N., Subbalakshmi, J., Chandra Sekhar, K.V.G.*Multicomponent cascade reaction: dual role of copper in the synthesis of 1,2,3-triazole tethered benzimidazo[1,2-a]quinoline and their photophysical studies. RSC Advances, 2016, 6, 15884-15894.
Goh, W., Gardner, C. R., Chandra Sekhar, K.V.G.,Biswas, N. N., Shashidhar, N., Rice, S.C., Willcox, M., Black, D. S., Kumar, N., Synthesis, quorum sensing inhibition and docking studies of 1,5-dihydropyrrol-2-ones. Bioorganic & Medicinal Chemistry, 2015, 23, 7366-7377.
Mahalakshmi Naidu, K., Nagesh, H.N., Singh, M., Sriram, D., Yogeeswari, P., Chandra Sekhar, K.V.G.*Novel amide and sulphonamide derivatives of 6-(piperazin-1-yl)phenanthridine as potent Mycobacterium tuberculosis H37Rv inhibitors. European Journal of Medicinal Chemistry, 2015, 92, 415-426.
Nagesh, H.N., Suresh, N., Bhanu Prakash, G.V.S., Gupta, S., Rao, J.V., Chandra Sekhar, K.V.G.* Design, synthesis and biological evaluation of novel phenanthridinyl piperazine triazoles via click chemistry as anticancer agents. Medicinal Chemistry Research 2015, 24, 523-532.
Mahalakshmi Naidu, K., Suresh, A., Subbalakshmi, J., Sriram, D., Yogeeswari, P., Chandra Sekhar, K.V.G.* Raghavaiah, P. Design, synthesis and antimycobacterial activity of various 3-(4-substituted sulfonylpiperazin-1-yl)benzo[d]isoxazole derivatives. European Journal of Medicinal Chemistry, 2014, 87, 71-78.
Nagesh, H.N., Suresh, A., Sairam, S.D.S.S., Sriram, D., Yogeeswari, P., Chandra Sekhar, K.V.G.*Design, synthesis and antimycobacterial evaluation of 1-(4-(2-substitutedthiazol-4-yl)phenethyl)-4-(3-(4-substitutedpiperazin-1-yl)alkyl)piperazine hybrid analogues. European Journal of Medicinal Chemistry, 2014, 84, 605-613.
Nagesh, H.N., Suresh, N., Mahalakshmi Naidu, K., Arun, B., Sridevi, J.P., Sriram, D., Yogeeswari, P., Chandra Sekhar, K.V.G.* Synthesis and evaluation of anti-tubercular activity of 6-(4-substitutedpiperazin-1-yl) phenanthridine analogues. European Journal of Medicinal Chemistry, 2014, 74, 333-339.
Suresh, N., Nagesh, H.N., Renuka, J., Rajput, V., Sharma, R., Khan, I.A., Chandra Sekhar, K.V.G.* Synthesis and evaluation of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-(2-(4-substitutedpiperazin-1-yl)acetyl) piperazin-1-yl)quinoline-3-carboxylic acid derivatives as anti-tubercular and antibacterial agents. European Journal of Medicinal Chemistry, 2014, 71, 324-332.
Suresh, N., Nagesh, H.N., Anil Kumar, Shirazi, A.N., Parang, K., Chandra Sekhar, K.V.G.* Synthesis of novel ciprofloxacin analogues and evaluation of their anti-proliferative effect on human cancer cell lines. Bioorganic & Medicinal Chemistry Letters, 2013, 23 (23), 6292-6295.
Nagesh, H.N., Mahalakshmi Naidu, K., Harika Rao, D., Sridevi, J.P., Sriram, D., Yogeeswari, P., Chandra Sekhar, K.V.G.* Design, synthesis and evaluation of 6-(4-((substituted-1H-1,2,3-triazol-4-yl)methyl)piperazin-1yl) phenanthridine analogues as antimycobacterial agents. Bioorganic & Medicinal Chemistry Letters, 2013, 23 (24), 6805-6810.
Chandra Sekhar, K.V.G.,* Rao V.S., Conrad W. D., Nagesh, H. N., Sreedhar Kumar, V., Divya Sridhar., Brust P., Murali Krishna M., Synthesis, Preliminary in vitro and in vivo pharmacological evaluation of4-{4-[2-(4-(2-substitutedquinoxalin-3-yl)piperazin-1-yl]ethyl) phenyl}thiazoles as atypical antipsychotic agents. Medicinal Chemistry Research 2013, 22 (4), 1660-1673.
Chandra Sekhar, K.V.G.,* V.S., Tara Sasank, T. V. N. V., Nagesh, H.N., Suresh, N, Mahalakshmi Naidu, K., Suresh, A., Synthesis of 3,5-diarylisoxazoles under solvent-free conditions using iodobenzene diacetate. Chinese Chemical Letters, 2013, 24 (12), 1045 -1048.
Chandra Sekhar, K.V.G.,* Vyas, D. R. K., H N Nagesh, Rao. V.S., Pharmacophore Hypothesis for Atypical Antipsychotics. Bulletin of Korean Chemical Society, 2012, 33 (9), 2930-2936.
Chandra Sekhar, K.V.G.,* Rao V.S., Kumar, D., Synthesis of Triazolo Quinoxalines as Antitubercular Agents. Korean Chem. Soc. 2011, 32 (8), 2657-2660.
Chandra Sekhar, K.V.G.,* Rao V.S., Conrad W. D., Satish Reddy A., Brust P., Murali Krishna M. Design, Synthesis and Preliminary in vitro and in vivo pharmacological evaluation of 2-{4-[4-(Substituted thiazolyl)phenylethyl] piperazin-1-yl}-1,8-naphthyridine-3-carbonitriles as atypical antipsychotic agents, Journal of Enzyme Inhibition & Medicinal Chemistry, 2011, 26 (4), 561-568.
Chandra Sekhar, K.V.G.,* Rao V.S., Satish Reddy, A., Sunandini, R., Kumar Satuluri, V.S.A., Solvent Free Microwave Accelerated Synthesis of Heterocyclic Thiazolidin-4-ones as Antimicrobial and Antifungal Agents. Bulletin of Korean Chemical Society 2010, 31 (5), 1219-1222.
Chandra Sekhar, K.V.G.,* Rao V.S., Murali Krishna Kumar M., Synthesis and preliminary screening of novel N-{2-[4-(substituted)piperazin-1-yl]-2-oxoethyl}acetamides as potential atypical antipsychotic agents. Journal of Enzyme Inhibition & Medicinal Chemistry, 2009, 24(3), 871-875.
Chandra Sekhar, K.V.G.,* Rao V.S., Ravi Kumar Vyas, D., Murali Krishna Kumar M., Synthesis and preliminary pharmacological evaluation of N-2-(4-(4-(2-substitutedthiazol-4-yl) piperazin-1-yl)-2-oxoethyl)acetamides as novel atypical antipsychotic agents. Bioorganic & Medicinal Chemistry Letters, 2008, 18, 6054-6057.
Rao, V.S., Chandra Sekhar K.V.G.,* Iodobenzene diacetate mediated solid-state synthesis of Heterocyclyl 1,3,4-oxadiazoles. Synthetic Communications, 2004, Vol.34 (12): 2153-2157.
Kumar, D., Chandra Sekhar, K.V.G., Dhillon, H., Rao, V.S., Varma, R.S., An expeditious synthesis of 1-aryl-4-methyl-1,2,4-triazolo [4,3-a] quinoxalines under solvent-free conditions using iodobenzene diacetate. Green Chemistry, 2004, Vol. 3: 156-157.
Sriram, D., Rao, V.S., Chandra Sekhar, K.V.G., Yogeeswari, P. Progress in the Research of Artemisinin and its analogues as antimalarials: An Update, Natural Product Research, 2004, Vol.18 (6): 503-527.
Rashmi P., Shaw A.K., Bhaduri A.P., Chandra Sekhar K. V. G., Anil S., Kishore K. S., Vineeta C., Ranjana S., Brahm S. S., Shalini A., Sudhir S., Higher Acyclic Nitrogen containing Deoxy sugar derivatives: A new lead in the generation of antimycobacterial chemotherapeutics. Bioorganic & Medicinal Chemistry, 2002, Vol 10 (6): 1695-1702.

Conference Articles

Pranali Vijaykumar Kuthe, Mohammed Muzaffar-Ur-Rehman, Murugesan Sankaranarayanan, Kondapalli Venkata Gowri Chandra Sekhar, Integrative Homology, AI-Based Modelling of PfSET3 and Virtual Screening of Microbial Metabolite-Derived Inhibitors as Potential Anti-Malarial Agents. Schrodinger Educator's Week 2026, April 28 - 30, 2026 (Virtual meet).
Adinarayana Nandikolla, Yogesh Mahadhu Khetmalis, Shreyash Rajendra Moharir, Kondapalli Venkata Gowri Chandra Sekhar, Tuberculosis in the Era of Drug Resistance: Insights of Medicinal Chemistry from our Research Endeavours, emerging Trends in Chemical Sciences -2026, Sardar Patel University, Vallabh Vidyanagar, 23-24 January 2026 (Invited Talk).
Kosana Sai Chaitanya, Naresh Kumar and Kondapalli Venkata Gowri Chandra Sekhar, Exploring Indole-derivatives as Potential Quorum Sensing Inhibitors for Combating Pseudomonas aeruginosa. 25^th Tetrahedron Symposium, Bruges, Belgium, July 1-4, 2025.
Hrushikesh Chaudhari, Kondapalli Venkata Gowri Chandra Sekhar, Computational Exploration of Aspartate-1-Decarboxylase (PanD) Inhibitors as Potential Anti-Tubercular Agents. 35^th Chemical Research Society of India National Symposium in Chemistry. Department of Chemistry, IIT Gandhinagar, July 3-5, 2025.
John Paul J, Kosana Sai Chaitanya, Kondapalli Venkata Gowri Chandra Sekhar, Sindhu S, Computational Investigation of Metal-Free π-Conjugated Terpyridines for
Multifunctional Organic Electronic Applications. International Conference on Molecular Materials: Trails, Perspectives, and Reminiscences (MolMat:TPR 2025), BITS Pilani Hyderabad Campus, July 4-5, 2025.
Shreyash Rajendra Moharir, Mahesh Kumar Talamadla, Vivek Sharma, Kondapalli Venkata Gowri Chandra Sekhar, Drug Design to Docking: An Integrated Approach to 2-(1H-Pyrazol-1-yl)pyrimidine Based Anticancer Agents. International Conference on Molecular Materials: Trails, Perspectives, and Reminiscences (MolMat:TPR 2025), BITS Pilani Hyderabad Campus, July 4-5, 2025.
N V M Rao Bandaru, Mahesh Kumar Talamadla, Franz-Josef Meyer-Almes, Kondapalli Venkata Gowri Chandra Sekhar, Rational Design and Synthesis of Substituted Benzyl Triazolopyridines as Selective HDAC8 Inhibitors. International Conference on Molecular Materials: Trails, Perspectives, and Reminiscences (MolMat:TPR 2025), BITS Pilani Hyderabad Campus, July 4-5, 2025.
Jatin Malik, Kondapalli Venkata Gowri Chandra Sekhar, Murugesan Sankaranarayanan, Repurposing Clinically Approved Drugs Against Trypanothione Reductase for Leishmaniasis: An Integrated Approach Using Molecular Docking, Dynamics, and Network Pharmacology. Second International E-Conference on Exploring Frontiers of In-Silico Drug Discovery: Trends, Challenges & Opportunities. Ramaiah University of Applied Sciences, Bengaluru, April 26-27, 2025.
Shreyash Rajendra Moharir, Kosana Sai Chaitanya, Kondapalli Venkata Gowri Chandra Sekhar,

Advancing Green Organic Syntheses Through Alternative Reaction Conditions. National Seminar on Green Chemistry and Sustainable Laboratory Practices (GCSLP-2025). Sardar Patel University, Vallabh Vidyanagar, 03 March 2025 (Invited Talk).

Shreyash Rajendra Moharir, Yogesh Mahadu Khetmalis, Vivek Sharma, Franz-Josef Meyer-Almes, Kondapalli Venkata Gowri Chandra Sekhar, Advancing Breast Cancer Therapy: Tetrahydroisoquinoline-Based Hydroxamate Derivatives as Potent and Selective HDAC6 Inhibitors. Current Trends in Drug Discovery Research, Central Drug Research Institute, Lucknow, February 19-22, 2025.
Mahesh Kumar Talamadla, Boddupalli Venkata Siva Kumar, Kondapalli Venkata Gowri Chandra Sekhar, Exploration of pyrido[2,3-d]-pyrimidines as anti-tubercular agents. Current Trends in Drug Discovery Research, Central Drug Research Institute, Lucknow, February 19-22, 2025.
Ala Chandu, Pragya Gupta, Chandra Sekhar Kondapalli Venkata Gowri, Sivaprakash Ramalingam, Murugesan Sankaranarayanan. Computational Exploration of DNA-DNMT1 Intercalators for Sickle Cell Disease: An E-pharmacophore Approach. Conference on Recent Trends in Drug Discovery (CRTDD-2025). BITS Pilani Pilani Campus, February 22-24, 2025 (Oral Talk).
Kosana Sai Chaitanya, Kondapalli Venkata Gowri Chandra Sekhar, Design, Synthesis, and Biological Evaluation of Novel Indole-based 1,2,3-triazoles as Quorum-sensing Inhibitors against Pseudomonas aeruginosa. Conference on Recent Trends in Drug Discovery (CRTDD-2025). BITS Pilani Pilani Campus, February 22-24, 2025 (Oral Talk).
Jatin Malik, Kondapalli Venkata Gowri Chandra Sekhar, Rafael Balaña-Fouce, Sankaranarayanan Murugesan, Design, Synthesis, and Evaluation of Nitro-Substituted Thiochromene Carboxamide Analogs as Potential Anti-Leishmanial Agents. Conference on Recent Trends in Drug Discovery (CRTDD-2025). BITS Pilani Pilani Campus, February 22-24, 2025.
Hrushikesh Chaudhari, Kondapalli Venkata Gowri Chandra Sekhar, Investigating Aspartate-1-decarboxylase (PanD) inhibitors as anti-tubercular agents: Computational insights through molecular dynamics, docking, quantum chemical methods, and in-silico ADMET studies, 8th Annual conference Of the Society for The Study of Xenobiotics, BITS Pilani Hyderabad Campus, January 23-25, 2025.
Hrushikesh Chaudhari, Muthyala Murali Krishna Kumar, Kondapalli Venkata Gowri Chandra Sekhar, 3-Cyano-2-(piperazin-1-yl)-1,8-naphthyridine analogues as potent anti-tubercular agents: Synthesis, Biological Evaluation, and In silico Docking Studies. International Conference on “Emerging Trends in Biopharmaceuticals and Translational Research for Human Health” & 18^th Annual Convention of Association of Biotechnology and Pharmacy, Mangalyatan University, Aligarh, December 19-21, 2024.
Kondapalli Venkata Gowri Chandra Sekhar, Kosana Sai Chaitanya, Srinivasarao Singireddi, Naresh Kumar, Unlocking the Power of Nitrogenic Heterocycles: A New Frontier in Quorum Sensing Inhibition in Pseudomonas aeruginosa. International Conference on “Emerging Trends in Biopharmaceuticals and Translational Research for Human Health” & 18^th Annual Convention of Association of Biotechnology and Pharmacy, Mangalyatan University, Aligarh, December 19-21, 2024. (Invited Talk).
Boddupalli Venkata Sivakumar, Mahesh Kumar Talamadla, and Kondapalli Venkata Gowri Chandra Sekhar, Analogues of 2-phenyl-3-((1-substituted-1H-1,2,3-triazol-4-yl) methoxy) quinoxaline as Mycobacterium tuberculosis H37Ra inhibitors. Cross Fertilisation between Academia and Industry: Towards Safer and Efficient Catalytic Processes. Indo-French International Symposium, BITS Pilani Hyderabad Campus, October 24-26, 2024.
N V M Rao Bandaru, Franz-Josef Meyer-Almes, Kondapalli Venkata Gowri Chandra Sekhar, Design, Synthesis, and Biological Evaluation of Selective HDAC8 Inhibitors, Cross Fertilisation between Academia and Industry: Towards Safer and Efficient Catalytic Processes. Indo-French International Symposium, BITS Pilani Hyderabad Campus, October 24-26, 2024.
Yogesh Mahadu Khetmalis, Franz-Josef Meyer-Almes_, Kondapalli Venkata Gowri Chandra Sekhar, Novel Quinazolin-4(3H)-One-Based Histone Deacetylase 6 (HDAC6) Inhibitors for Anticancer Activity, 31^st INDO-US International conference on Global Trends and Challenges in Drug Design, Nanotechnology and Pharmaceutical Sciences, March 19, 2024. (Best Oral Presentation Award)
Ala Chandu, Sivaprakash Ramalingam, Kondapalli Venkata Gowri Chandra Sekhar, Murugesan Sankaranarayanan, Computational Exploration of Epigenetic Targets: E-Pharmacophore Modeling for DNMT1 Inhibition in Sickle Cell Disease, International Conference on Integrating Novel Approaches for Non-Communicable Disease Target Exploration INNOVATE-2024, BITS Pilani, Pilani Campus, March 7-9, 2024
Yogesh Mahadu Khetmalis, Muthyala Murali Krishna Kumar,Sankaranarayanan Murugesan, Kondapalli Venkata Gowri Chandra Sekhar, Novel Functionalised Oxindole Analogues as Antimycobacterial Agents, 32^nd CRSI National Symposium in Chemistry (CRSI-NSC-32), BITS Pilani, Pilani Campus, February 1-4, 2024
Yogesh Mahadu Khetmalis, Surendar Chitti, Kondapalli Venkata Gowri Chandra Sekhar, Design, Synthesis and Pharmacological Evaluation of Novel Spiro-Chromanone Analogs Against Mycobacterium tuberculosis H37Ra, National Symposium on Convergence of Chemistry & Materials (CCM-2023), January 6-7, 2023.
Ranita Roy, Adinarayana Nandikolla, K.V.G. Chandra Sekhar, Gopal Chakrabarti, Spirochromanone, a Novel spiro- heterocyclic Compound Targeting Tubulin-Microtubule System in HeLa Cells by Binding to Tubulin, 91st Annual Meeting of the Society of Biological Chemists. December 8 - 11, 2022.
Yogesh Mahadu Khetmalis, Surendar Chitti, Kondapalli Venkata Gowri Chandra Sekhar, Design and Synthesis of Imidazo[1,2-a]pyridine Analogues as Anti-tubercular Agents, International Conference on Recent Trends and Future Opportunities in Pharmaceuticals. November 10 - 12, 2022.
Kosana Sai Chaitanya, Surendar Chitti, and Kondapalli Venkata Gowri Chandra Sekhar, Design, Synthesis and Anti-mycobacterial Evaluation of Benzo-[d]-imidazo-[2,1-b]-thiazole and Imidazo- [2,1-b]-thiazole carboxamide triazole Analogues, International Conference on Recent Trends and Future Opportunities in Pharmaceuticals. November 10 - 12, 2022.
Karankumar, Faheem, S. Murugesan, and K. V. G. Chandra Sekhar. Preliminary investigation of drug repurposing as a direction towards anti-Leishmanial drug discovery, International Conference on Drug Discovery (ICDD2020), BITS-Hyderabad, 29^thFebruary-2^nd March 2020.
Adinarayana, S. Srinivarao, N. Sridhar, S. Murugesan, and K. V. G. Chandra Sekhar. Design, synthesis and biological evaluation of 2-aminobenzimidazoles as Quorum Sensing inhibitors in Pseudomonas aeruginosa.26^th Indian Society for Chemists and Biologists Conference jointly organized with 5^th Nirma Institute of Pharmacy International Conference, Ahmadabad, 22^nd-24^th January 2020.
Karankumar, Faheem, G. Surajpyarelal, S. Murugesan, and K. V. G. Chandra Sekhar. In-silico target identification study of novel anti-leishmanial β-carbolineagents. 26^th Indian Society for Chemists and Biologists Conference jointly organized with 5^th Nirma Institute of Pharmacy International Conference, Ahmadabad, 22^nd-24^th January 2020.
Faheem, G. Surajpyarelal, B. Karankumar, S. Murugesan, and K. V. G. Chandra Sekhar. In-silico target identification study of novel anti-leishmanial agents. 26^thIndian Society for Chemists and Biologists Conference jointly organized with 5^th Nirma Institute of Pharmacy International Conference, Ahmadabad, 22^nd-24^th January 2020.
V. G. Chandra Sekhar, S. Srinivasarao, S. Murugesan, and Naresh Kumar. Nitrogen based heterocycles as bacterial Quorum Sensing inhibitors in Pseudomonas aeruginosa. National Conference on New Frontiers in Chemistry - From Fundamentals to Applications (NFCFA2019), BITS, Goa, 20^th-22^ndDecember 2019. (Invited talk)
Adinarayana, S. Srinivarao, S. Murugesan, and K. V. G. Chandra Sekhar. 5,6-Dimethyl-2-aminobenzimidazoles as bacterial Quorum Sensing inhibitors in Pseudomonas aeruginosa. National Conference on New Frontiers in Chemistry - From Fundamentals to Applications (NFCFA2019), BITS, Goa, 20^th-22^ndDecember 2019.
Yogesh, C. Surendar, and K. V. G. Chandra Sekhar. 2-(3,4-dimethoxyphenyl)-6(1,2,3,6-tetrahydropyridin-4-yl)imidazo[1,2-a]pyridine analogues as antiproliferative agents. National Conference on New Frontiers in Chemistry - From Fundamentals to Applications (NFCFA2019), BITS, Goa, 20^th-22^ndDecember 2019.
Adinarayana, S. Srinivarao, H. N. Nagesh, S. Murugesan, and K. V. G. Chandra Sekhar. Deprotection of Methylene Nitrile Using Elemental Sulfur: Novel Strategy in Preparation of 1,2,3-triazoles. National Symposium on Convergence of Chemistry & Materials (CCM), BITS-Pilani Hyderabad campus, Hyderabad, 17-18^thDecember 2019.
Srinivasarao, G. Balaram, S. Murugesan and K.V.G. Chandra Sekhar. Design and synthesis of novel 1,2,3-triazole based quorum sensing inhibitors using molecular hybridization approach against Pseudomonas aeruginosa.20th Tetrahedron International Symposium - Bangkok, Thailand, 17-21st June 2019.
V.G. Chandra Sekhar,S. Srinivas Rao,andS. Murugesan. Design, Synthesis and Biological Evaluation of triazole containing Salicylic acid as Quorum Sensing Inhibitors against P.aeruginosa. 6^th International Conference on Chemistry – Our Health, Our Future, organised by Indian Council of Chemists at Paris, France, June 06-08^th, 2019. (Invited talk).
Adinarayana, S. Murugesan and K.V.G. Chandra Sekhar, 3,4-Dihydroisoquinoline benzylidenes and 3,4-dihydroquinoline phenyl acetamides as potent Leishmanial inhibitors. 24th CRSI National Symposium in Chemistry, organized by CLRI and IIT Madras at Chennai, February 8-10th, 2019.
Adinarayana, S. Srinivas Rao, H. N. Nagesh, S. Murugesan and K.V.G. Chandra Sekhar, One-Pot Synthesis of 4-Substituted-2H-1,2,3-triazoles by Deprotection of Methylene Nitrile using elemental sulfur. Drug Discovery in India 2019 - Breakthrough Research in Medicinal Chemistry, organized by Selectbio Sciences India Pvt. Ltd., Mumbai, January 17-18th, 2019.
Srinivas Rao, A. Suresh and K.V.G. Chandra Sekhar, N. Adinarayana, H. N. Nagesh, S. Murugesan and K.V.G. Chandra Sekhar, Seeking potential Quorum Sensing Inhibitors against Pseudomonas aeruginosa: Design, Synthesis and QSI activity of various triazoles. Drug Discovery in India 2019 - Breakthrough Research in Medicinal Chemistry, organized by Selectbio Sciences India Pvt. Ltd., Mumbai, January 17-18th, 2019.
Rishi,A. Suresh and K.V.G. Chandra Sekhar, Design and synthesis of 1,2,3-triazolyl sulfonyl analogues as anti-tubercular agents. 24th ISCB International Conference organized by Manipal University, Jaipur, January 11-13th, 2018.
Srinivas Rao, A. Suresh and K.V.G. Chandra Sekhar, Design and synthesis of 1,2,3-triazolyl 9H-fluorenone analogues as anti-tubercular agents. National Symposium on Emerging Trends and Innovations in Pharmaceutical Science (ETIPS-2017) in chemistry, organized by JNTU Hyderabad, October 12-13, 2017. (Won the best paper award in oral section).
Srinivas Rao, A. Suresh and K.V.G. Chandra Sekhar, Design and synthesis of 1,2,3-triazolyl 9H-fluorenone analogues as anti-tubercular agents. National Symposium on Convergence of Chemistry & Materials (CCM-2017) in chemistry, organized by BITS-Pilani, Hyderabad campus, December 21-22, 2017.
Surendar, A. Suresh and K.V.G. Chandra Sekhar, Design and Synthesis of Indole, Oxindole and Isoxazole Derivatives as Quorum Sensing Inhibitors against P.aeruginosa. National Symposium on Convergence of Chemistry & Materials (CCM-2017) in chemistry, organized by BITS-Pilani, Hyderabad campus, December 21-22, 2017.
Ravikiran, R. Punna Rao, B. Mayank, K.V.G. Chandra Sekhar, Analysis of formaldehyde – a human carcinogen in drug substance using ultra-high-performance liquid chromatograph. National Symposium on Convergence of Chemistry & Materials (CCM-2017) in chemistry, organized by BITS-Pilani, Hyderabad campus, December 21-22, 2017.
Srinivas Rao, A. Suresh, K. Mahalakshmi Naidu, Napiórkowska Agnieszka, Augustynowicz-Kopec Ewa, Sankaranarayanan Murugesan, Subhash Chander,Rangan Krishnan and K.V.G. Chandra Sekhar, Identification and development of 1,2,3-triazole derivatives of fused pyrazole-dihydropyridine as Mycobacterium tuberculosis Pantothenate synthetase inhibitors. 21^st National Symposium in Chemistry, organized by CRSI at Indian Institute of Chemical Technology, Hyderabad, July 13-16, 2017.
V.G. Chandra Sekhar,S. Srinivas Rao,K. Mahalakshmi Naidu,Shashidhar Nizalapur, Naresh Kumar, Design and Synthesis of Indole, Oxindole and Isoxazole Derivatives as Quorum Sensing Inhibitors against P.aeruginosa.5^th International Conference on Current Concepts in Chemistry, organised by Indian Council of Chemists at Bali, Indonesia, June 07-09^th, 2017. (Invited talk).
V.G. Chandra Sekhar,Nitrogen based Heterocycles as anti-tubercular agents, National Conference on “Organic Chemistry in Sustainable Development: Recent Advances and Future Challenges (OCSD-2016) organized by Chemistry department, BITS Pilani, August 29-30, 2016. (Invited talk).
Surendar, A. Suresh and K. V. G. Chandra Sekhar, Design and synthesis of novel fluconazole triazole analogues as anticancer agents. National Conference on “Organic Chemistry in Sustainable Development: Recent Advances and Future Challenges (OCSD-2016) organized by Chemistry department, BITS Pilani, August 29-30, 2016.
Srinivas Rao, K. Mahalakshmi Naidu, A. Suresh, K.V.G. Chandra Sekhar. Synthesis and biological activity of 6-(piperazin-1-yl)phenanthridine sulphonamide derivatives as potent anti-tubercular agents. International Symposium on Bioorganic Chemistry (ISBOC-10), Indian Institute of Science Education and Research, Pune, January 11-15^th, 2015.
V.G.Chandra Sekhar, A.Suresh, K.Mahalakshmi Naidu, S. Srinivas Rao. Synthesis and characterization of new tetrazole derivatives as anti-tubercular agents. International Symposium on Bioorganic Chemistry(ISBOC-10), Indian Institute of Science Education and Research, Pune, January 11-15^th, 2015. (Invited talk)
Suresh, A. Kumar, K. Parang,M. Alvala, K.V.G. ChandraSekhar. Synthesis and anticancer evaluation of novel ciprofloxacin analogues. International Conference on Innovations in Chemical Research and Applied Chemical Sciences at Smt. Chandibai Himathmal Mansukhani College, Ulhasnagar-3, Mumbai, January 12-13^th, 2015. (Won the best paper award in poster section).
Mahalakshmi Naidu, H.N. Nagesh, S. Srinivasarao, A. Suresh, N.Suresh, D. Sriram, K.V.G. Chandra Sekhar, Design, synthesis and biological evaluation of novel Phenanthridine amide analogues as potent anti-tubercularagents. 13^th Eurasia Conference on Chemical Sciences at Indian Institute of Science, Bangalore, India, December 14 - 18^th 2014.
N. Nagesh, A. Suresh, D. Sriram, P. Yogeeswari, K.V.G. Chandra Sekhar. A new hybrid approach for design, synthesis and evaluation of substituted phenethylthiazole derivatives as antitubercular agents. 15^thTetrahedron Symposium - Asian Edition on Challenges in Bioorganic and Organic Medicinal Chemistry organised by Elsevier at Singapore Expo, Singapore, October 28 -31^st, 2014.
V.G. Chandra Sekhar, A. Suresh, H.N.Nagesh, N.Suresh, K.Mahalakshmi Naidu, D.Sriram, P.Yogeeswari. Design, Synthesis and anti-tubercular activity of various Phenanthridine analogues. 3rd International Conference on chemistry for sustainable development: Indian perspective, organised by Indian Council of Chemists at Dubai, United Arab Emirates, June 10-14^th, 2014. (Invited talk)
N.Nagesh, K.Mahalakshmi Naidu, A. Suresh, J.Subbalakshimi, D.Sriram, P.Yogeeswari, K.V.G. Chandra Sekhar. Design, synthesis and anti-tubercular evaluation of novel benzo[d]isoxazole hybrid analogues. International conference on drugs for the Future: Infectious Diseases, Antimicrobial Drug Discovery: Challenges and perspectives DFID-2014, NIPER, Hyderabad, March 27-28^th, 2014.
Mahalakshmi Naidu, A. Suresh, N.Suresh, H.N.Nagesh, K.V.G. Chandra Sekhar. Design, synthesis and in vitro antifungal evaluation of novel ciprofloxacin derivatives. 5^thNational seminar on Bioinformatics, Sri Venkateshwara Institute of Medical Sciences, Tirupati, February 14-15^th, 2014. (Won the best paper award in poster section).
Mahalakshmi Naidu, H.N.Nagesh, N.Suresh, A. Suresh, K.V.G. Chandra Sekhar, Synthesis and evaluation of phenanthridine analogues as anti-tubercular agents. 16^thCRSI Symposium in Chemistry, IIT Bombay, February 7 -9^th, 2014.
Suresh, H.N.Nagesh, N.Suresh, K.Mahalakshmi Naidu, D.Sriram, P.Yogeeswari, K.V.G.Chandra Sekhar. Synthesis and anti-tubercular activity of 6-(4-substitutedpiperazin-1-yl) phenanthridine analogues. International conference on Chemical Biology, Disease mechanisms and Therapeutics (IICB-2014), Indian Institute of Chemical Technology, Hyderabad, February 6-8^th, 2014.
V.G. Chandra Sekhar, N Suresh, H.N.Nagesh, K.Mahalaxmi Naidu, A. Suresh, K. Parang, Design and synthesis of 1-cyclopropyl-6-fluoro-4-oxo-7-{4-substituted piperazin-1-yl}-1, 4-dihydro quinoline-3-carboxylic acid derivatives asAntiproliferative agents. National Poster- II Symposium on Advances in Organic / Medicinal Chemistry (AOMC-2013), Krishna University, Vijayawada, December 21^st, 2013. (Invited talk)
Suresh, H.N.Nagesh, K.Mahalaxmi Naidu, Inshad Ali Khan, K.V.G. Chandra Sekhar, Design and synthesis of 1-cyclopropyl-6-fluoro-4-oxo-7-{4-substituted piperazin-1-yl}-1, 4-dihydro quinoline-3-carboxylic acid derivatives as Anti-tubercular agents, 2nd UK-India MedChem Congress, IICT Hyderabad, March 22-23^rd, 2013.
N. Nagesh, K. Mahalakshmi Naidu, N. Suresh, K.V.G. Chandra Sekhar, Design and synthesis of novel phenanthridine derivatives as anticancer agents, 19^thISCB International Conference (ISCBC – 2013), Mohanlal Sukhadia University Udaipur, March 2-5^th, 2013.
Mahalakshmi Naidu, H.N. Nagesh, N.Suresh, K.V.G. Chandra Sekhar, Synthesis Of Benzisoxazolylpiperazines as dopamine D2 antagonists, CTDDR 2013 : 5^thInternational Conference on Drug Development and Orphan/Neglected Diseases, CDRI Lucknow, February 26-28^th, 2013.
Suresh, H.N.Nagesh, K.Mahalaxmi Naidu, K.V.G. Chandra Sekhar, Design and synthesis of 1, 3-disubstituted 5-(2-(4-substituted piperazine-1-yl) acetyl) indoline-2-one derivatives as anti-cancer agents, 15^thCRSI National Symposium in Chemistry, Banaras Hindu University – Varanasi, February 1-3^rd, 2013.
Suresh, H.N.Nagesh, K.Mahalakshmi Naidu, K.V.G. Chandra Sekhar, Design and Synthesis of 1-cyclopropyl-6-fluoro-4-oxo-7-{4-substituted piperazin-1-yl}-1,4-dihydro quinoline-3-carboxylic acid derivatives as anti-tumor agents, 6^thMidyear CRSI Symposium in Chemistry, CDRI Lucknow, July 21-22^nd, 2012.
N. Nagesh, N.Suresh, K. Mahalakshmi Naidu, V.S. Rao, K.V.G. Chandra Sekhar, Synthesis of Phenanthridinyl piperazines as novel Dopamine D2 antagonists. 14^thCRSI National Symposium on Chemistry, CSIR-NIIST, Thiruvananthapuram, February 3-5^th, 2012.
K V G Chandra Sekhar, V S Rao, T V N V Tara Sasank, V Sreedhar Kumar, An Expeditious Synthesis of 3,5-Diarylisoxazoles under solvent-free conditions using Iodobenzene diacetate. 13^thCRSI National Symposium on Chemistry, NISERKIIT University, Bhubaneshwar, February 4-6^th, 2011. (Invited talk)
K V G Chandra Sekhar, V S Rao, V Sreedhar Kumar, Design, Synthesis and Pharmacological Evaluation of substituted quinoxalines as Atypical Antipsychotics. 62^ndIndian Pharmacutical Congress, Manipal, December 17-19^th, 2010, p.B239.
V Sreedhar, V S Rao, W Deuther-Conrad, P Brust, K V G Chandra Sekhar, Design, Synthesis and Preliminary in vitro and in vivo Pharmacological Evaluation of quinoxalinylthiazoles as Atypical Antipsychotic Agents, 5th Midyear CRSI Symposium in chemistry, Trivendrum, July 23-24^th, 2010.
K V G Chandra Sekhar, V S Rao, Winnie Deuther-Conrad, Peter Brust, Design, Synthesis and Preliminary in vitro and in vivo Pharmacological Evaluation of 2-{4-[4-(substitutedthiazolyl)phenylethyl]piperazin-1-yl}-1,8-naphthyridine-3-carbonitriles as Atypical Antipsychotic Agents. 12th CRSI National Symposium in Chemistry, Indian Institute of Chemical Technology, Hyderabad, India, February 4-7^th, 2010.
V.G. Chandra Sekhar, V. S. Rao, M. Murali Krishna, R. Mahesh, Synthesis of N-{2-[4-(substituted)piperazin-1-yl]-2-oxoethyl}acetamides as novel D2 Antagonists: International conference on the interface of chemistry – biology in Biomedical Research, BITS, Pilani, February 22-24^th, 2008, p212. (Invited talk)
V.G. Chandra Sekhar, V.S. Rao and D. Ravi Kumar Vyas, Pharmacophore Hypothesis for Atypical Antipsychotics: International conference on the interface of chemistry – biology in Biomedical Research, BITS, Pilani, February 22-24^th, 2008, p202.
V. G. Chandra Sekhar, V. S. Rao, Anisha Thomas, A. Satish Reddy, R. Sunandini, V.S.A. Kumar Satuluri, Solvent Free Microwave Assisted Synthesis of 3-(2-methylquinoxalin-3-yl)-2-(substitutedphenyl)thiazolidin-4-ones: International conference on the interface of chemistry – biology in Biomedical Research, BITS, Pilani, February 22-24^th, 2008, p125. (Invited talk)
Satish, A., K V G Chandra Sekhar, A.Ashok Kumar, V S Rao, Process development of chloroethyl phenylthiazole derivatives – intermediates of novel potential atypical antipsychotics agents: National Symposium on Challenges In Drug Discovery Research: Networking Oppurtunities Between Academia & Industries, BITS, Pilani. April 3-4^th, 2006, p 44.
Ashok Kumar, V S Rao, K V G Chandra Sekhar, Vipul Jain. A Cost-effective synthesis of 9-Fluorenone oxime using conventional and microwave approaches: National Symposium on Challenges In Drug Discovery Research: Networking Oppurtunities Between Academia & Industries, BITS, Pilani. April 3-4^th, 2006, p 46.
S.Rao, K.V.G.Chandra Sekhar, Divya Sridhar and Dalip Kumar, Microwave Assisted Synthesis of Isonicotinoyl Hydrazones. International Symposium on Recent Advances In Drug Design & Delivary Systems, BITS, Pilani, February 26-27^th, 2005, p38-39.
S.Rao, K.V.G.Chandra Sekhar, A.Ashok Kumar and Dalip Kumar, Synthesis of 1-aryl-4-methyl-1,2,4-triazolo[4,3-a]quinoxalines as Antitubercular Agents: International Symposium on Recent Advances In Drug Design & Delivary Systems, BITS, Pilani, February 26-27^th, 2005, p33-34.
V.G. Chandra Sekhar, V.S. Rao, Harmeet Dhillon, A. Ashok kumar, Iodobenzene diacetate mediated synthesis of Triazolo Quinoxalines: National Conference for Pharmacy Students, Current Research in Academic Institutions, Shri Vishnu College of Pharmacy, Bhimavaram, March, 7-8^th, 2003, p1.

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