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Prof. P Yogeeswari

Senior Professor, Department of Pharmacy,
Dean, Administration
Shri B.K. Birla and Smt. Sarala Birla Chair Professor
Chairperson, Institutional Animal Ethics Committee

Cancer, Biophysical characterization, Molecular pharmacology, Neurotoxicity screening, Anti-inflammatory screening, Anti-Cancer screening, Nerve conduction velocity, Neurochemical estimations in different regions of brain, CNS Behavioral and cognition screening, Neuropathicpain, Anticonvulsant screening, Dengue virus, Hepatitis C virus, Tuberculosis, Alzheimer’s Disease, Epilepsy, Duchenne Muscular Dystrophy, Fetal Alcohol spectrum disorder (FASD), Fragile X syndrome, Autism spectrum disorder (ASD), Neuropathic pain including Diabetic neuropathy
Birla Institute of Technology and Science- Pilani, Hyderabad Campus Jawahar Nagar, Shameerpet Mandal, R.R. District, Pin-500078, INDIA

 

About 
 
Qualification
  • Ph. D. (Medicinal Chemistry), Institute of Technology, Banaras Hindu University, Varanasi, India, 2001.
  • Master of Pharmacy (Medicinal Chemistry), Banaras Hindu University, India, 1998.
  • Bachelor of Pharmacy, The Tamilnadu Dr. M.G.R. Medical University, Chennai, India, 1996 (State Topper, Gold medalist).
Awards:
  1. Recipient of "Most Prominent Contributors to Innovation" presented at the World Innovation Congress 2023 and citation endorsed by Asian Innovation Congress & Awards, The Business Leader of the Year and World Sustainability, Feb 2023.
  2. One of the top 75 women entrepreneurs of the country profiled in a Coffee Table book released by Prime Minister during the 7 th foundation day ceremony of BIRAC in 2022.
  3. First runner up of TiE Global Women Entrepreuner Pitching Competition 2022.
  4. South India Women Achiever's Award for 2019 under the category of "Outstanding Educator" received on 22nd December 2019 at Chennai organised by Syrafills.
  5. TiE-BIRAC WinER Award 2019 for Women in Entrepreneurial Research received at the 7th Foundation Day Ceremony of BIRAC on 19th March 2019, New Delhi, India.
  6. Best Paper Award in the Category of Food Research Jan 2019-at the International Conference on Biotechnological Innovations in Food and Healthcare, 27-28 January 2019, Dubai, UAE.
  7. Recipient of Outstanding Research Faculty Award for the academic year 2017-18 certified by Careers 360 in the Pharmacology, Toxicology and Pharmaceutics discipline as one of the top 10 knowledge producers in India.
  8. Received "Prof. Indira Parikh 50 Women in Education Leaders" at the World Education Congress 2017 held at Taj Lands, Mumbai on 23rd November 2017.
  9. Recipient of Women in Education Award presented at the Dewang Mehta National Education Awards function held at Institute of Public Enterprises, Hyderabad on 15th April 2017.
  10. Recipient of BILL and MELINDA GATES FOUNDATION GLOBAL HEALTH TRAVEL AWARD 2017 to present paper at the Keystone Symposium on Cancer Immunology and Immunotherapy at British Columbia, Canada in March 2017.
  11. Received i3 Gold Award for Best Innovator of the year 2016 at the 8th India Innovation Initiative conducted by CII, DST, AICTE and Yi at New Delhi, 18-19th Oct 2016.
  12. Recipient of BITSAA Prof. Venkateswaran Faculty Excellence Award for the year 2015.  
  13. Awarded the Best Drug Discovery Innovation for the start up idea at the International Knowledge Millennium Conference 2015 (IKMC2015): Spreading the Innovation Spirit at Hyderabad, 2-3 Nov 2015.
  14. International Association for the Study of Pain conferred an Award for Excellence in Pain Research and Management in Developing Countries  under the Basic Science research category received at the 15th World Congress on Pain, Buenos Aires, Argentina, October 2014. (View in this link http://www.iasp-pain.org/Meetings/Content.aspx?ItemNumber=3291&navItemNumber=3297.
  15. Recipient of INDIAN COUNCIL OF MEDICAL RESEARCH “Shakuntala Amir Chand Prize 2010” for excellent biomedical research honored in August 2013.
  16. Recipient of "YOUNG PHARMACY TEACHER OF THE YEAR 2007awarded by the Association of Pharmacy Teachers of India.
  17. Best Paper in Podium presentation was awarded in the 11th APTI national Convention held in September 1-3, 2006 at Bangalore for the paper entitled "Synthesis of 4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N-(substituted phenyl)butanamides possessing antiallodynic and antihyperalgesic activities in two rat models of neuropathic pain".
  18. Recipient of "Young Scientist" by Department of Science & Technology, Government of India under Fast track Funding scheme.
  19. Recipient of “Sevaratna” Dr. R.Venkatesalu Gold Medal for securing First rank in B.Pharm of The Tamilnadu Dr. M.G.R. Medical University.
  20. Recipient of Tamilnadu Pharmacy Scientific Trust, Chennai Gold Medal for Topper in B.Pharmacy in the Tamilnadu State
  21. Recipient of First Prize award in Tamilnadu State, Chennai. for B.Pharmacy awarded by The Tamilnadu Pharmacy Council
  22. Awarded Junior Fellowship by the UGC during the period 1996-1998.
  23. Awarded Senior Research Fellowship by the UGC during the period 2000-2001.
 Professional Recognition:
  1. Organiser of "International Conference on Drug Discovery (ICDD) 2020" in association with Schrodinger Inc, USA at BITS Pilani, Hyderabad campus, 29th Feb-2nd March 2020.
  2. Jury Member of the Prestigious initiative of Merck Young Scientist Award 2019 & 2021.
  3. Nominated Member, Steering Committee, Rajasthan State Level Implementation of Startup Policy Drafting and Commissioning of iStart Program since September 2017.
  4. Member, Board of Studies, Anurag Group of Institutions since 2019.
  5. Member, Board of Studies, JNTU, Hyderabad since 2019.
  6. Program Committee member of "World Congress on Cancer Research"  held at Goa on 5-7 October, 2017.
  7. Scientific Advisory Committee MemberInternational Conference on Trend Setting Innovations in Chemical Sciences & Technology-Applications in Pharma Industry (TSCST-2015) held on 16-18 December 2015 under TEQIP-II, JNTUH, Hyderabad
  8. Expert Reviewer, Neurobiology projects, DBT, Govt. of India
  9. Scientific Reviewer, "International Conference on Computational Intelligence and Soft Computing" Organised by Institute of Bioinformatics and Computational Biology, Vishakapatnam, 19-20 Dec 2015.
  10. Resource person, "Brainstorming Session on Retrosynthesis", at the National Conference on Infectious Diseases- A Medicinal Chemistry Perspective, sponsored by DST & KSCTC held on 29-30 Aug 2014, AIMS, Kochi.
  11. Expert Reviewer, "International Conference on Computational Intelligence: Health and Diseases" Organised by IBCB, Vishakapatnam, 27-28 Dec 2014, Andhra University, A.P. 
  12. Program Technical Committee Member3rd ScienceOne Conference on Drug Discovery and Development (SCDDD) 2014, Jan 21-24, Dubai.
  13. Commisioning Editor of an international journal, "International Journal of Drug Design & Discovery" published by Pharma Book Syndicate, India.
  14. Member, Institutional Ethical Committee, Molecular Diagnostics, Counselling, Care & Research Centre, Coimbatore, India
  15. Chairperson, Institutional Ethical Committee, Army College of Dental Sciences, Hyderabad, India
  16. Editorial Advisory Board Member of an international journal, "Recent Patents on CNS Drug Discovery" published by Bentham Science Publishers (USA & The Netherlands).
  17. Editorial Advisory Board Member of an international journal, "International Journal of Pharmaceutical Analysispublished by Bioinfo Publishers, USA.
  18. Editorial Board Member of an international journal "International Journal of Biomedical Sciences" published by Master publishing group, USA.
  19. Editorial Board Member of an international journal "Therapeutic Targets for Neurological Disorders" published by Smart Science & Technology, USA.
  20. Editorial Board Member of an international journal "The Pharma Professionals" published by Clinfocus Research Pvt. Ltd., India
  21. Member, Association of Biotechnology Led Enterprises (ABLE)
  22. Member, Confederation of Women Entrepreuners (COWE)
  23. Member, International Brain Research Organization (IBRO)
  24. Member, Canadian Pharmaceutical society
  25. Member, International Association for the Study of Pain (IASP)
  26. Life Member, Indian Pharmacological Society (IPS)
  27. Life Member of Association of Pharmacy Teachers of India (APTI)
  28. Member,  Board of Studies for Pharmaceutical Sciences,  JNTU, Hyderabad.
  29. Ph.D. Examiner, JNTU, Hyderabad
  30. Expert reviewer of the International journals of

       ·         Journal of Medicinal Chemistry (ACS, USA)

·         Journal of Chemical Information & Modeling (ACS, USA)

·         European Journal of Medicinal Chemistry (Elsevier)

·         Bioorganic Medicinal Chemistry (Elsevier)

·         Drug Discovery Today (Elsevier)

·         Recent Patents on CNS Drug Discovery (Bentham)

·         Current Enzyme Inhibition (Bentham)

·         Acta Pharmacologica Sinica (Blackwell Publishing)

·         Brain Research (Elsevier) 

·         International Journal of Biomedical Science (Master Publishing group, USA)

·         Archive der Pharmazie (Wiley VCH)

·         European Journal of Pain (Elsevier)

·         Brain Research (Elsevier)

·         Medicinal Research Reviews (Wiley)

·         Expert Opinion on Drug Discovery (Informa Health)

·         Expert Opinion on Drug Safety (Informa Health)

·         Archive der Pharmazie (Wiley)

·         Drug Discovery Today (Elsevier)

 

 

Courses

 

 Higher Degree Courses
  • IPR and Pharmaceuticals 
  • Advanced Medicinal Chemistry
  •  Computer-Aided Drug Design
  • Advanced Pharmacology
  • Laboratory Projects
  • Chemistry of Macromolecules
  • Advanced Pharmaceutical Chemistry
  • Structure & Reactivity of Organic Compounds(As a part of WILP program of BITS delivered to Matrix Laboratories, Hyderabad)
First Degree Courses
  • Introduction to Molecular Biology and Immunology
  • Medicinal Chemistry-I
  • Medicinal Chemistry-II
  • Natural Drugs        
  • Chemistry of Organic Compounds
  • Medicinal Chemistry
  • Phytochemistry
  • Anatomy, Physiology & Health Education
  • Pharmaceutical Analysis
  • Measurement Techniques-I (Chemistry)
  • Chemistry-II

 

 

Research Interest

Drug Design and Synthesis

· Various New Targets of Neurological disorders that include
i. Neuropathic pain including Diabetic neuropathy
ii. Autism spectrum disorder (ASD)
iii. Fragile X syndrome
iv. Fetal Alcohol spectrum disorder (FASD)
v. Duchenne Muscular Dystrophy
vi. Epilepsy,
vii. Alzheimer’s Disease,

· Various New Targets for
i. Tuberculosis
ii. Hepatitis C virus
iii. Dengue virus
iv. Cancer

Drug Screening
i. Anticonvulsant screening
ii. Neuropathicpain
iii. CNS Behavioral and cognition screening
iv. Neurochemical estimations in different regions of brain
v. Nerve conduction velocity
vi. Anti-Cancer screening
vii. Anti-inflammatory screening
viii. Neurotoxicity screening
ix. Molecular pharmacology
x. Biophysical characterization

 

 

Research Collaborations
· National Institute of Health, Bethesda, USA
· National Cancer Institute, USA
· National Institute of Mental Health and Neurosciences, Bangalore, India
· Indian Institute of Science, Bangalore, India.
· National Institute of Immunology, New Delhi, India
· Karolinska Institute, Stockholm, Sweden
· The University of Queensland, Australia
· Department of Ophthalmology & Visual Science, University of Illinois, Chicago, USA
· Dongduk Women's University, Seoul, Korea
· Pasteur Institute, University of Lille, France
· University of KwaZulu Natal, Durban, South Africa
· Federal University of Para, Belem, Brazil
· Bogomoletz Institute of Physiology National Academy of Science, Ukraine
· Faculty of Medicine of Porto, Porto, Portugal
· Instituto Nacional de Ciencia e Technologia em Tuberculosis, MCT/CNPq, Porto Alegre, Brazil
· Incozen Therapeutics Pvt. Ltd, Hyderabad
· Rutger's The State University of New Jersey, New Jersey Medical School, Newark, New Jersey, USA
· Basavatarakam Indo-US Cancer Hospital, Hyderabad, India
· Army College of Dental Sciences, Hyderabad

 

 

Publications
Total Publications: 318
Books/Chapters in Book : 4
Research Papers, Reports : 308
Patents: 6
h index: 41
Citations: 6885 (As on 10 July 2018)

BOOKS & Chapters in BOOK
1. D. Sriram, P. Yogeeswari, Textbook on Medicinal Chemistry, 2e, 2010, Pearson Education Singapore Ltd.
2. Book Chapter: P. Yogeeswari and D. Sriram, SUSTAINABILITY IN HIGHER EDUCATION THROUGH BASIC SCIENCE RESEARCH -STRATEGIES FOR CORPORATE BODIES IN PHARMACEUTICALS in Evolving Corporate Education Strategies for Developing Countries: The Role of Universities, Released in Jan 2013 by IGI Global- Officially released by the Hon'ble Minister of Human Resources Development , Government of India, SRI PALLAM RAJU in May 2013
3. Book Chapter: P. Purkayastha, A. Rallapalli, N.L. Bhanu Murthy, A. Malapati, P. Yogeeswari, D. Sriram, EFFECT OF FEATURE SELECTION ON KINASE CLASSIFICATION MODELS in Computational Intelligence in Medicial Informatics, Springer Singapore, 2015.
4. Book Chapter: P. Purkayatha, S. Varanasi, A. Malapati, P. Yogeeswari, D. Sriram, EFFECT OF PHYSIOCHEMICAL PROPERTIES ON CLASSIFICATION ALGORITHMS FOR KINASES FAMILY in Chapter COMPUTATIONAL INTELLIGENCE IN DATA MINING- Volume 2, Volume 411 of the Series Advances in Intelligent Systems and Computing Series, Springer, 2016, pp 47-57.

PATENTS:
1. Yogeeswari, P.,Sriram, D., Kumar, A.S.K. et al., Novel N-Spiro substituted compounds. Indian Patent 263536 (Granted on 5th Nov 2014)
2. Yogeeswari, P., Sriram, D., Madhubabu, B., Brahmam, M., Indian Patent Application No. 2945/DEL/2014 (15/10/2014): A Compound for treating inflammatory neuropathic pain and cancer.
3. Saketh, D.V.S., Srikanth, V., Yogeeswari, P., Sriram, D., Indian Patent Application No. 5707/CHE/2014 (13/11/2014): Novel compounds as modulators of AKT.
4. Yogeeswari, P., Sriram, D., Hasitha, S.A., Brahmam, M., Indian Patent Application No. 1763/DEL/2015 (12/06/2015): Cathepsin D inhibitors and compositions thereof for treating breast cancer.
5. Vinay K. Nadicoori, Vijay S., Yogeeswari, P., Sriram, D., Indian Patent Application No. 3167/DEL/2015 (01/10/2015): Novel compounds with antitubercular potential.
6. Yogeeswari, P., Parameshwar Reddy, A., Dwivedi, S. Indian Patent Application No. E-136359/2019-DEL (28/08/2019): Compounds for the treatment of inflammation and process for preparing the same.

CRYSTAL STRUCTURES:

Crystal Structures of the Ligand Designed in our CADD lab published in pdb.
1. 3ZEI: Structure of the Mycobacterium tuberculosis O-Acetylserine Sulfhydrylase (OASS) CysK1 in complex with a small molecule inhibitor5AKWCrystal structure of TNKS2 in complex with 2-(4-chlorophenyl)-1,2,3,4- tetrahydroquinazolin-4-oneCrystal structure of TNKS2 in complex with 2-(4-(propan-2-yl)phenyl)- 1H,2H,3H,4H-pyrido(2,3-d)pyrimidin-4-one
2. Structure of the Mycobacterium tuberculosis O-Acetylserine Sulfhydrylase (OASS) CysK1 in complex with a small molecule inhibitor5AKWCrystal structure of TNKS2 in complex with 2-(4-chlorophenyl)-1,2,3,4- tetrahydroquinazolin-4-oneCrystal structure of TNKS2 in complex with 2-(4-(propan-2-yl)phenyl)- 1H,2H,3H,4H-pyrido(2,3-d)pyrimidin-4-one: Structure of the Mycobacterium tuberculosis O-Acetylserine Sulfhydrylase (OASS) CysK1 in complex with a small molecule inhibitor5AKWCrystal structure of TNKS2 in complex with 2-(4-chlorophenyl)-1,2,3,4- tetrahydroquinazolin-4-oneCrystal structure of TNKS2 in complex with 2-(4-(propan-2-yl)phenyl)- 1H,2H,3H,4H-pyrido(2,3-d)pyrimidin-4-one
3. 5AL1: Crystal structure of TNKS2 in complex with 2-(4-tert-butylphenyl)-1H, 2H,3H,4H-pyrido(2,3-d)pyrimidin-4-one
4. 5AL2: Structure of the Mycobacterium tuberculosis O-Acetylserine Sulfhydrylase (OASS) CysK1 in complex with a small molecule inhibitor5AKWCrystal structure of TNKS2 in complex with 2-(4-chlorophenyl)-1,2,3,4- tetrahydroquinazolin-4-oneCrystal structure of TNKS2 in complex with 2-(4-(propan-2-yl)phenyl)- 1H,2H,3H,4H-pyrido(2,3-d)pyrimidin-4-one
5. 5AL3: Crystal structure of TNKS2 in complex with 2-(2,4-dichlorophenyl)-1- methyl-1H,2H,3H,4H-pyrido(2,3-d)pyrimidin-4-one
6. 5AKU: Crystal structure of TNKS2 in complex with 2-(4-tert-butylphenyl)-1,2, 3,4-tetrahydroquinazolin-4-one
7. 5AL4: Crystal structure of TNKS2 in complex with 2-(4-methylpiperazin-1-yl)- 3,4,5,6,7,8-hexahydroquinazolin-4-one
8. 5AL5: Crystal structure of TNKS2 in complex with 2-(4-((pyridin-4-yl)methyl) piperazin-1-yl)-3,4,5,6,7,8-hexahydroquinazolin-4-one

Click here for more information.

 

 

Completed Projects
1. DST Fast Track for young scientist- DESIGN OF NEW ANTICONVULSANTS: SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF ARYL SEMICARBAZONES AND ITS ANALOGUES- 2004-2007| Principal Investigator
2. CSIR project - SYNTHESIS AND NEUROPHARMACOLOGY OF 4-AMINOBUTYRIC ACID ANALOGUES-2006-2009| Principal Investigator
3. CSIR project- DEVELOPMENT OF NEW GENERATION QUINOLONE MOLECULES AGAINST MYCOBACTERIUM TUBERCULOSIS- 2005-2008|Co-Investigator
4. UGC Major project-DESIGN AND SYNTHESIS OF NEWER GABA ANALOGUES FOR TREATING CNS DISORDERS- 2007-2010|Principal Investigator
5. ICMR project-DESIGN AND SYNTHESIS OF NOVEL NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS FOR THE TREATMENT OF AIDS AND OPPORTUNISTIC INFECTIONS ASSOCIATED WITH AIDS INCLUDING TUBERCULOSIS TUBERCULOSIS -2005-2008|Co-Investigator
6. OPEN SOURCE DRUG DISCOVERY (CSIR) Project-DESIGN AND SYNTHESIS OF NEW INBIBITORS OF MTB GLMU BY MODELING & HIGH THROUGHPUT DOCKING -2010-2011|Co-Investigator.
7. DBT CENTRE OF EXCELLENCE PROJECT- VIRTUAL CENTRE OF EXCELLENCE FOR TUBERCULOSIS RESEARCH (In collaboration with Indian Institute of Science, Bangalore & The Foundation for Medicial Research, Mumbai)-2007-2012|Co-Investigator
8. UGC Major project-ISOCITRATE LYASE ENZYME AS TARGET IN PERSISTENT MYCOBACTERIUM TUBERCULOSIS INFECTION: SYNTHESIS OF 2-ARYLTHIAZOLIDINE-4-CARBOXYLIC ACID AND 5-NITRO-2-FUROIC ACID DERIVATIVES AND ITS ANTIMYCOBACTERIAL EVALUATION-2009-2012|Co-Investigator
9. CSIR project- DEVELOPMENT OF NOVEL DNA GYRASE INHIBITORS AGAINST MYCOBACTERIUM TUBERCULOSIS AND OTHER NON-TUBERCULOSIS MYCOBACTERIAL INFECTIONS -2010-2013|Co-Investigator
10. DBT Neuroresearch Project- STRUCTURE-GUIDED DESIGN OF NOVEL NON-PEPTIDIC NONCOVALENT SELECTIVE INHIBITORS OF THE SPINAL MICROGLIAL CATHEPSIN S FOR THE TREATMENT OF NEUROPATHIC PAIN-2011-2013| Principal Investigator
11. DST Project- STRUCTURE-BASED RATIONAL DESIGN AND SYNTHEIS OF MYCOBACTERIUM TUBERCULOSIS PANTOTHENATE SYNTHETASE INHIBITORS-2011-2014| Co-Investigator
12. DST INDO-BRAZILIAN_SOUTH AFRICAN-DEVELOPMENT, SYNTHESIS, AND TESTING OF NOVEL ANTI-HIV DRUGS-2011-2014| Co-Investigator
13. DBT Project- DISCOVERY OF NOVEL MODULATORS OF NAD(+) DEPENDENT PROTEIN DEACETYLASE SIRT1 FOR THE TREATMENT OF VARIOUS HUMAN DISORDERS -2011-2014|Principal Investigator
14. CSIR project- DESIGN AND SYNTHESIS OF PHARMACOPHORIC HYBRIDS AS POTENTIAL LEADS FOR THE TREATMENT OF NEUROPATHIC PAIN-2012-2015|Principal Investigator
15. DBT INDO-SWEDEN Project-STRUCTURE-GUIDED DESIGN OF NEW ANTIBACTERIAL AGENTS AGAINST DORMANT MYCOBACTERIUM TUBERCULOSIS-2009-2014 |Co-Investigator
16. ICMR project- DEVELOPMENT OF DRUGS FOR THE TREATMENT OF LATENT PHASE OF TUBERCULOSIS- 2011-2014| Co-Investigator
17. DST Major Research Project- DRUG DISCOVERY OF INHIBITORS OF THE PROTEASE OF PERIPHERAL MACROPHAGES AND MICROGLIAL CELLS IN THE SPINAL CORD FOR THE TREATMENT OF NEUROPATHIC PAIN- 2011-2015| Principal Investigator.
18. DST INDO-UKRAINE JOINT PROJECT-DEVELOPMENT OF ANTIEPILEPTIC LEADS TO SUPPRESS HIPPOCAMPAL EPILEPTIC SEIZURES-2012-2015|Principal Investigator.
19. DBT RGYI project-NON-INVASIVE DELIVERY OF siRNA TO TREAT MELANOMA-2012-2015|Co-Investigator
20. OPEN SOURCE DRUG DISCOVERY-CSIR-DEVELOPMENT AND ANALYSIS OF NOVEL INHIBITORS AGAINST MTB GlmU- 2012-2015| Co-Principal Investigator (In Collaboration with NII, New Delhi, and IIT- Kanpur)
21. ICMR-INSERM (Indo-France) project- STRUCTURE-BASED DESIGN OF ORPHAN NUCLEAR RECEPTOR MODULATOR TO TREAT DIABETES AND ITS COMPLICATIONS BY TARGETING RORALPHA AND REV-ERBALPHA-2014-2016| Principal Investigator
22. DBT INDO-SWEDEN new project- STRATEGIES AGAINST ANTIBIOTIC RESISTANCE IN MYCOBACTERIUM TUBERCULOSIS AND PSEUDOMONAS AERUGINOSA: NEW DRUG FOR OLD TARGETS AND OLD DRUGS FOR NEW TARGETS- 2014-2017|Co-Investigator
23. DST INDO-PORTUGAL project- DEVELOPMENT OF NOVEL COMPOUNDS FOR THE TREATMENT OF NEURAL COMPLICATIONS OF DIABETES-2014-2017| Principal Investigator
24. DBT INDO-BRAZIL project - ENZYMES FROM PURINE AND PYRIMIDINE BIO-SYNTHETIC PATHWAY AS TARGETS FOR THE DEVELOPMENT OF MYCOBACTERIUM TUBERCULOSIS DRUGS-2014-2017| Principal Investigator
25. DST INDO-POLISH project- MYCOBACTERIAL TUBERCULOSIS ACETYL COENZYME A CARBOXYLASE INHIBITORS: STRUCTURE-BASED DRUG DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION- Approved| Co-Investigator

Ongoing projects
Co-Investigator, DBT project entitled "MRI based non-invasive quantitative
biomarker for early diagnosis and prognosis of brain tumor"- In Collaboration with EEE/ECE Department, BITS Pilani, Hyderabad campus
Industry sponsored projects
1. ASTRA ZENCA, Bangalore- Development of New Antitubercular agents-2010-2013(COMPLETED)
2. ADITYA BIRLA GROUP, Mumbai- Structure-based rational design and synthesis of inhibitors of various enzymes Mycobacterium tuberculosis - 2011-2014 (COMPLETED)
3. Incozen Therapeutics Ltd, Hyderabad - Development of Novel Antiinflammatory Agents-2012-2015 (COMPLETED)

 

 

 

Invited Talks

 

  1. Invited Talk on "Academician to Entrepreneurship- Journey from Research to Innovation" delivered on 19th April 2022 for students of Biotechnology, BITS Pilani Hyderabad campus.
  2. Panelist and Speaker on "The new landscape of Academic Innovation and Entrepreneurship" as a part of Merck's Science to Solution Series on 24th March 2022. Online Event
  3. Invited speaker on "Breast Cancer Therapeutics: Drug Discovery and Innovation" at the International Conference on Integrating Pharma Education and Research in Developmental Therapeutics" on 23rd March 2022, Hyderabad, India
  4. Speaker at the "Through the Windows of the World: Life with COVID-19" conducted by International Affairs, South Dakota University, Virtual Event, 19th February 2021.
  5. Speaker at the EO GSEA 2020 on " Women in Entrepreneurship" via Facebook Live on 11th November 2020.
  6. Speaker at VIMARSH 2020 on " Managing Work Life Balance : Story of A Woman Entrepreneur’s Life" Online event conducted by Startup Chaupal, Gurugram, India,  12th September 2020.
  7. Speaker on "Drug discovery using ligand and structure-based  Combination: Lead Discovery and Optimization" at the Drug Discovery Hackathon 2020 Training Program, Virtual Event, 17-21 August 2020. 
  8. Guest Speaker at the APC Online Convention 2020 on " Drug Discovery Tools and Strategies" for Pharmacy Students across the country (India) and panelist. 15-20 May 2020.
  9. Speaker at the E-Conference on "Hacks to Convince your Parents for a Dream Career" hosted by REMARKABLE EDUCATION, 18th April 2020.
  10. Guest Speaker at the Pfizer Annual RA Meet to speak on "Transforming Millennials as Future Leaders" 5th March 2020, Chennai, India
  11. Speaker on "Protein Structure Modeling and Case Studies on Drug Discovery" at the National Workshop on Recent Trends in Bioinformatics for Exploratory Analysis and Visualisation of Biological Data, 16-18 January 2020, Hyderabad, India.
  12. Speaker on "Drug Design Strategies to design ligands for glioblastoma and brain cancer" at the International Conference on Oncology and Virology, 13-14 December 2019, Bangkok, Thailand.
  13. Speaker on "Drug Design Strategies using Target based and Ligand based Modeling" at the National Conference on Computational Approaches in drug discovery and development for immune disorders, 8-9 March 2019, AIMS, Cochin, Kerala, India.
  14. Speaker on "Role of Academia in Nurturing Innovation" at the FLYNIP2K19: Workshop on Innovation and Entrepreneurship organized by NIPER, Hyderabad and RICH on 8th February 2019, Hyderabad, India
  15. Invited Speaker and Resource person at the Startup Conclave: Young Entrepreneurship Pharmacy Conclave held on 16th November 2018, Al Shifa College of Pharmacy, Malappuram, Kerala, India
  16. Session Speaker on "Biology: Life Guardian of the future technology developments" at the Education Fair 2018 conducted by Delhi Public School, Nacharam on 27th October 2018, Hyderabad, India 
  17. Speaker on "Multiple crystal structure modeling in Structure-based Drug Discovery: Case studies on successful diverse lead identification" at the 18th International Conference on Medicinal and Pharmaceutical Chemistry held in 18-19 October 2018, Dubai, UAE
  18. Chief Guest and Speaker on "Therapeutic Intervention of Migraine Pain, a Drug Discovery Approach" at a one week Faculty Development Programme on Recent Trends in Drug Discovery and Targeting Drug Delivery System in associate with APTI, Telangana, 1-6 October 2018, Hyderabad, India.
  19. Resource Person and Speaker on "Drug discovery tools using crystal structure analyses: Case studies" at Pharmacy Council of India sponsored continuing education programme (CEP) held on 10-12 September 2018, Sultan Ul-Uloom College of Pharmacy, Hyderabad, India.
  20. Invited speaker on "Cancer Research at BITS-Pilani, Hyderabad campus, Centre for Human Diseases group activities" delivered at RICH Cancer Conference and Innovation Challenge Programme held on 21 August 2018 at CSIR-IICT, Hyderabad, India.
  21. Panelist on the topic " Necessity of Women's Education" moderated by Prof. Indira  Parikh at the World Education Congress 2017 held on 23rd Nov 2017 at Mumbai, India
  22. Invited speaker on "Pharmacological Intervention to study the effect of antinociceptive curcumin analogues in a rat model of migraine"  delivered at the 8th Annual Congress of NeuroTalk-2017 (NT-2017) on 22-24 May 2017, Barcelona, Spain.
  23. Invited speaker on "Multiple crystal structures a boon to structure-based drug discovery: Diverse lead identification using diverse e-pharmacophore modeling" to be delivered at the International Conference on Drug Design organised by Schrodinger on 7-9 April 2017, New Delhi, India
  24. Plenary Lecture delivered on the topic "Discovery of new small molecule inhibitors of HIV protease: Multiple pharmacophore modelling, 3D-QSAR and virtual screening" at the Prof. K.V. Thomas Endowemnet International Syumposium on New Trends in Applied Chemistry (NTAC-2017), on 9-11 February 2017, Cochin, India
  25. Invited speaker at the "30th Annual Meeting of Society for Neurochemistry, India (SNCI)", National Conference on Recent Trends in Neurological and Psychiatric Research" on 9-11 December 2016, CSIR-CCMB, Hyderabad, India
  26. Keynote speaker on "FT-IR application in Pharmaceutical Analysis" delivered at the Two Day National Workshop on Applications of Advanced Analytical Techniques in Pharmaceutical Sciences and Nanotechnology (AATPN) on 16-17 September 2016, JNTU, Hyderabad, India.
  27. Guest of honor and Invited speaker on "Protein data bank and their utilization in Structure-based drug design: Multiple crystal structures to design anti-HIV agents, a case study" delivered at the 2nd National Training Program on Prinicples and Practice of Molecular Modelling in Teaching and Research on 21-23 July 2016 at Andhra University College of Pharmaceutical Sciences, Vishakapatnam, India.
  28. Speaker on "Methodologies of Research and Tools and Techniques of Research" delivered at the 2-day "Workshop on Research Methodology" organized by Centre of Excellence in Water Resource Management, BITS-Pilani, Hyderabad campus on 11-12 April 2016, Hyderabad, India.
  29. Technical Speaker on "Computer-aided drug design tools to optimize candidate therapeutics efficiently" delivered at the National Level Seminar BIOADHYAYAN-2016, on 28 January 2016, organised by Avanthi College of Pharmacy at Sundarraya Vignana Kendram, Baghlingampally, Hyderabad, India.
  30. Invited Speaker on "Leveraging Multiple Crystal Structures for Efficient Structure-based Drug Design: An Insight with Case Studies" delivered at the UGC sponsored Short term course on "In-Silico Drug discovery and structure-based drug design in pharmaceutical chemistry", 2 Nov 2015 till 7 Nov 2015, at Centre for Pharmaceutical Sciences, IST, JNTUH, Hyderabad, India
  31. Invited Speaker on "Sponsored Research Grants: Importance and Logisitcs" delivered for Research Methodology Workshop as a part of the 1st Telangana Association of Oral and Maxillofacial Surgeons of India, 21 August 2015, Hyderabad, India.
  32. Speaker and Panelist at "Multi-Disciplinary Research (MDR) Talks" organized by BITS EMBRYO, BITS-Pilani, Hyderabad campus on 10th April 2015, Hyderabad, India.
  33. Invited Speaker on "Research Ethics, IPR and Research Funding Opportunities" delivered at the 2-day "Research Methodology Workshop" organized by Centre of Excellence in Water Resource Management, BITS-Pilani, Hyderabad campus on 3-4 April 2015, Hyderabad, India.
  34. Distinguished Speaker and Panelist at "Drug Discovery Conference: Showcasing India's Innovation PipelineBIOASIA2015 on 3rd February 2015, HICC, Hyderabad.
  35. Resource person and Speaker on "Sponsored Research Grants and Opportunities" at the "Workshop on Research Methodologies and Research Support" conducted by the Centre for Staff Training and Development (CSTD) at Dr. Ambedkar Open University, Hyderabad, 2-9 December 2014.
  36. Invited Resource person and Speaker in "Brainstorming session on Retrosynthesis" at the National Conference on Infectious Diseases-Medicinal Chemistry Perspective sponsored by DST & KSCTC, 29-30th August 2014, AIMS, Kochi, India.
  37. Guest Speaker on"Think Beyond your Reach- A walk through on BITS Pilani programmes" organized as a part of Career Counselling Session to school students at VMJ School on 4th June 2014, Madurai, India
  38. Invited Speaker on "IPR and Research Funding Opportunities" delivered at the 2-day "Research Methodology Workshop" organized by Centre of Excellence in Water Resource Management, BITS-Pilani, Hyderabad campus on 11-12 April 2014, Hyderabad, India.
  39. Invited Guest lecture on "Pharmacophore modeling at the crossroads of Ligand and Structure-based drug design strategies: A case study on HCV NS5B polymerase inhibitor design" delivered at the 2-Day Workshop on Computational Drug Design  organized by Department of Chemistry, University College of Science, Osmania University, as a part of Celebrating Noble Prize in Computational Chemistry on 3-4 April 2014, Hyderabad, India.
  40. Invited Guest and Speaker on "In-Silico Drug Design: A tool to Identify Novel Chemical Entities" delivered at the APSCHE Sponsored National Level Seminar on Recent Trends and Applications of Software Tools in Pharmacy at PHARMASAGRA,  on 9-10 Jaunary 2014, Karimnagar, India.
  41. Invited Speaker on "Computational tools to develop chemical libraries for Drug Discovery" delivered at the "National Conference on Frontiers of Chemical Research" organised by Department of Chemistry, JNTU, Hyderabad on 25-26 October 2013, Hyderabad, India.
  42. Invited Research Lecture on "Drug Design Strategies for therapeutic intervention of neurological disorders" delivered at Bogomoletz Institute of Physiology on 24th May 2013, Kiev, Ukraine.
  43. Guest lecture delivered on "Structure-based drug design approach for the identification of small molecule inhibitor of various HIV enzymes" delivered at K-RITH (KwaZulu-Natal- Research Institute for TB and HIV) on 25th February 2013, Durban, South Africa 
  44. Invited Speaker on "Pharmacophoric Hybrid Chemical Design using Aryl Semicarbazide Scaffold to Yield Multifunctional Leads for the Treatment of Various Neuropathic Pain Conditions" delivered at the National Symposium on Emerging Trends in Chemical Sciences sponsored by UGC, March 20, 2012, Indore, India. 
  45. Invited Speaker on " Targeting Microglial Cathepsin S for the treatment of neuropathic pain: Challenges and drug design strategies" delivered at the"Indo-UK Seminar on Innovative Medicines" organized by DST (India) and Royal Society (UK), November 14-15, 2011, Hyderabad, India
  46. Invited Talk delivered on the topic "In-Silico Drug Design as an Emerging Tool for Drug Discovery" at the "Seminar on Recent Developments in Pharmaceutical Sciences" organized by LV Prasad Eye Institute (LVPEI), Hyderabad,August 22, 2011 on account of celebrating Silver Jubilee year of the Institute, LVPEI campus,Hyderabad, India
  47. Guest Lecture delivered on the topic "Computer-Aided Drug Design: Basic Concepts and ApplicationsLalitha College of Pharmacy, Hyderabad, India, on 30th June 2011.
  48. Invited talk delivered on the topic "Pharmacophore Modeling as an Important Driving Tool in New Drug Discovery" to the Inter-disciplinary seminar group of Karolinska Institute, Stockholm Sweden, on November 1, 2010.
  49. Delivered an invited talk as Reseource Person on the topic "Molecular modelling & Drug design as an important tool in Drug Discovery" at the National Level Workshop on Tools for the Design & Synthesis of drugs sponsored by AICTEApril 22-24, 2010 at GR College of Pharmacy, Hyderabad
  50. Delivered a talk on "Drug Design using computational approach" at the QIP workshop sponsored by AICTE on 9th November 2009 at Manipal University, Manipal.
  51. Delivered a plenary lecture on "Molecular Modelling & Drug Design" at the AICTE sponsored National Conference on Emerging Trends in Pharmaceutical Sciences,February 27-28, 2009, Hyderabad
  52. Delivered to Torrent Research Centre on "Strategies for treating Neuropathic Pain at BITS, Pilani" on 15th March 2008.
  53. "Drug development Strategy for the treatment of Neuropathic Pain" delivered during the 12th International Conference on the Interface of Chemistry-Biologyin Biomedical Research (ISCBC), February 22-24, 2008, BITS, Pilani.
  54. Invited talk on "Drug development for treating neuropathic Pain by targeting GABA receptors" at the National Conference on Recent Trends of Research in Pharmaceutical Sciences7-8 Jan 2008, Nathdwara, Udaipur.
  55. "Drug Design based on Molecular Hybridization & Integration" delivered during the International Symposium on Drug design and Dug delivery Systems, BITS, Pilani, 26-27 Feb 2005.

 

 

 

Papers in Conferences

 

  1. Yogeeswari, P, Therapeutic Strategies and Drugs under Investigations for Triple Negative Breast cancer. 2nd Indo Oncology Summit (CME Accredited), 15-17 November 2019, Bhubaneshwar, Orissa.
  2. Dusane A., Dwivedi S., Yogeeswari, P, In-house mGluR5 inhibitors as a therapeutic approach towards Autism: In-silica and in-vitro investigations. IBRO-APRC Associate School on Blood-Brain Barrier: From Basic Physiology to Neurological Disorders, 4-9 November 2019, Chandigarh, India.
  3. Yogeeswari, P, High Quality Sweet Lime juice powder compositions with enhanced real fruit content and stability for food, pharmaceutical and cosmetic applications. International Conference on Biotechnological Innovations in Food and Healthcare, 27-28 January 2019, Dubai.  (Best Presentation Award)
  4. Yogeeswari, P, Multiple crystal structure modeling in structure-based drug discovery: Case studies on successful diverse lead identification. 18th International Conference on Medicinal and Pharmaceutical Chemistry, 18-19 October 2018, Dubai. 
  5. Sawle, A., Gangadhar M., Yogeeswari, P, Pharmacological intervention to study the effect of antinocicpetive curcumin analogue in a rat model of migraine. International Society for Neurochemistry-ESN meeting, 20-24 August 2017, Paris, France. (Travel partially supported by BITSAA)
  6. Dwivedi, S., Medishetty, R., Kulkarni, P., Yogeeswari, P, Zebrafish larvae model: A novel approach to study Autism. International Society for Neurochemistry-ESN meeting, 20-24 August 2017, Paris, France. (Travel supported by DST)
  7. Gangadhar, M., Isava, O., Yogeeswari, P, Antiinflammatory compound with SIPSC blocking potential: A promising therapeutic approach for neurological pain disorders. International Society for Neurochemistry-ESN meeting, 20-24 August 2017, Paris, France.
  8. Yogeeswari, P, Cathepsin D inhibitors as potential therapeutics for breast cancer treatment against triple negative and triple positice breast cancers. Keystone Symposium on Cancer Immunology and Immunotherapy: Taking place a mainstream oncology (C7-2017), 19-23 March 2017, Whistler, British Columbia, Canada. Accepted with BILL AND MELINDA GATES FOUNDATION GLOBAL HEALTH TRAVEL AWARD.
  9. Dwivedi, S., Medishetty, R., Kulkarni, P., Sriram, D., Yogeeswari, P, Zebrafish Larva model: A novel approach to study Autism. 2nd International Brain Research Organization (IBRO)/APRC Chandigarh School of Neuroscience, 14-22 December 2016, Chandigarh, India. WON THE THIRD BEST ORAL PRESENTATION AWARD.
  10. Sawale, A., Martharasala, G., Sriram, D., Yogeeswari, P, Screening studies of new chemical entities to evaluate their efficacy on rat model of migraine. 68th Indian Pharmaceutical Congress,  16-18 December 2016, Vishakapatnam, India. 
  11. Soni, V., Suryadevaraya, P., Samala, G., Singh, A., Yogeeswari, P, , Sriram, D., Nandicoori, V.K., Depletion of M. tuberculosis GlmU from infected murine lungs effects the clearance of the pathogen. BioAsia 2016, 8-10 February 2016, Hyderabad, India
  12. Shubham, D., Alokam, R., Srikanth, R., Piyush, B., Sriram, D, Yogeeswari, P,  Targeting orphan nuclear receptor RORA as a therapeutic option for Autism Spectrum Disorder. International Conference on "Cutting edge Pharmacology: Contemporary Issues and Future Challenges" & 48th Annual Conference of Indian Pharmacological Society, 18-20 December 2015, Rajkot, Gujarat. 
  13. Brahmam, M., Bobesh, K.A., Mikila, M., Reshma, S.L., Sriram, D, Yogeeswari, P, Development of 1,2,3-triazolo quinoline hybrid analogues as mycobacterial DNA gyrase inhibitors. Conference on Drug Discovery and Development : Global scenario-Indian Perspective, 20-21 November 2015, NIPER, Hyderabad.
  14. Reshma, S.R., Shalini, S., Yogeeswari, P, Sriram, D., Development of quinoline derivatives as potent Mtb lysine aminotransferase inhibitors targeting latent tuberculosis. Conference on Drug Discovery and Development : Global scenario-Indian Perspective, 20-21 November 2015, NIPER, Hyderabad.
  15. Bobesh, K.A., Reshma, S.R., Nikhila, M., Yogeeswari, P, Sriram, D., N-Benzyl-3,3-dimethoxyhexahydro-2H-furo[3,2-b]pyrrol-6-yl) methanesulfonamides as mycobacterial DNA gyrase inhibitors. Conference on Drug Discovery and Development : Global scenario-Indian Perspective, 20-21 November 2015, NIPER, Hyderabad.
  16. Srikanth, R., Alokam, R., Gangadhar, M., Susruth, J., Sriram, D, Yogeeswari, P, Design, Synthesis and Pharmacological evaluation of novel 1,3,5-triazine-2,4,6-triamine derivatives as potent and selective A2A adenosine receptor antagonists in the treatment of epilepsy. 7th Asian Association of Schools of Pharmacy (AASP) Conference, 30 October-2 November 2015, Taipei, Taiwan. 
  17. Hasitha, S.A., Battu, M.B., Yogeeswari, P.; Sriram, D. Identification of novel non-peptidic inhibitors for Cathepsin K in treatment of breast cancer bone metastasis: Pharmacophore-based 3D QSAR, molecular docking and biological evaluation. Gordon Research Conferences: Computer Aided Drug Design, 19-24 September 2015, Mount Snow in West Dover, VT, USA. 
  18. Srilakshmi, R.R., Sridevi, J.P., Yogeeswari, P.,  Sriram, D. Design, Synthesis and Biological evaluation of Benzothiazole derivatives as Mtb Lysine aminotransferase Inhibitors. National Conference on Drug Discovery and Development in Chemistry- Applications in Pharma Industry (DDDC-2015), 14-15 September 2015, Tirupati, India. 
  19. Brahmam, M., Renuka, J., Sridevi, J.P., Yogeeswari, P.,  Sriram, D. Development of novel quinolone p-phenylenediamine hybrid analogues mycobacterial DNA gyrase inhibitors to improve the cardio safety profile. National Conference on Drug Discovery and Development in Chemistry- Applications in Pharma Industry (DDDC-2015), 14-15 September 2015, Tirupati, India. 
  20. Bobesh, K.A., Renuka, J., Sridevi, J.P., Yogeeswari, P.,  Sriram, D. Substitution of the N-linked aminopiperidine class with piperazine moiety to the mycobacterial gyrase domain to reduce the hERG toxicity profile. National Conference on Drug Discovery and Development in Chemistry- Applications in Pharma Industry (DDDC-2015), 14-15 September 2015, Tirupati, India. 
  21. Gangadhar, M., Alokam, R., Sriram, D, Yogeeswari, P, MG2, a novel semicarbazone derivative, reduces neuropathic pain by inhibiting the expression levels of neuroinflammatory mediators. 2015 Keystone Symposia: C8: Pathways of Neurodevelopmental Disoders, 16-20 March 2015, California, USA.
  22. Gaus, A., Mishra, R.K., Alokam, R., Singhal, S.M., Sriram, D., Yogeeswari, P., Evaluation of 2,6-diaminopyrimidines as novel Rho kinase inhibitors using animal models of treatment of neurological disorders. 66th Indian Pharmaceutical Congress: India- Pharmacy of the World, 23-25 January 2015, Hyderabad, India. 
  23. Priyanka, P.; Aruna, M.; Banumurthy, N.L.; Yogeeswari, P.; Sriram, D. Effect of feature selection on Kinase Classification Models. International Conference on Computational Intelligence: Health and Diseases (CIHD), 27-28 December 2014, Vishakapatnam, India. 
  24. Priyanka, P., Reshma, A., Aruna, M., Yogeeswari, P., Sriram, D., Comparative modeling combined with Molecular dynamics and Docking studies to identify potent inhibitors of PKMzeta and Biological evaluation. 9th Brain Research Conference: Neuroprotection: Basic mechanism and translational potential, 13-14th November 2014, Washington DC, USA. 
  25. Ganesh, S.; Radhika, N.; Devi, P.B.; Yogeeswari, P.; Sriram, D. Design, synthesis and biological evaluation of 6-methylimidazo[2,1-b]thiazole-5-carboxylic acid derivatives as novel Mycobacterium tuberculosis pantothenate synthase inhibitors. 15th Tetrahedron Symposium- Asian Edition: Challenges in Bioorganic and Organic Medicinal Chemistry, 28-31 October 2014, Singapore. 
  26. Srikant, B., Methuku, S., Tharun, K.G., Shewta, M., Sridevi, J.P., Yogeeswari, P., Sriram, D.,  Chakraborti, A.K., Alpha-Sulphonamidophosphonates and bis alpha-aminophosphonates: New leads towards infectious disease chemotherapy. 248th ACS National Meeting & Exposition, 10-14 August, San Francisco, CA, USA.
  27. Renuka, J., JeanKumar, V., Bobesh, A., Vijay, S., Devi, P.B., Venkat, K.P., Priyanka, S., Keerthana, S., Pushkar, K., Yogeeswari, P., Sriram, D., Design and biological evaluation of novel antibacterial inhibitors against DNA GyrB from clinical isolates of Staphylococcus aureusGordon Research Conferences, 10-15th August 2014, Maine, USA.
  28. Srikanth, R., Reshma, A., Kulkarni, P., Sriram, D., Yogeeswari, P., Structure-based drug design, synthesis and screening of Adenosine A2A antagonists as novel antiepileptic agents. 11th European Congress on Epileptology, 29th June-3rd July 2014, Stockholm, Sweden
  29. Kakan, S.K., JeanKumar, V.U., Devi, P.B., Shalini, S., Sriram, D., Yogeeswari, P., Targeting Mycobacterium tuberculosis Lysine aminotransferase: Design, synthesis and in vitro evaluation of small molecule compounds. International Conference on "Drugs for the Future: Infectious Diseases", Antimicrobial Drug Discovery: Challenges and Perspectives, 27-28 March 2014, NIPER, Hyderabad, India. (WON THE BEST PAPER IN POSTER SECTION)
  30. Shravan, M, Renuka, J., Yogeeswari, P., Sriram, D., Design and biological evaluation of novel Staphylococcus aureus DNA gyrase inhibitors. International Conference on "Drugs for the Future: Infectious Diseases", Antimicrobial Drug Discovery: Challenges and Perspectives, 27-28 March 2014, NIPER, Hyderabad, India.
  31. Devi, P.B., Saxena, S., Sriram, D., Yogeeswari, P., Screening and Identification of Potent Inhibitors against pantothenate synthetase- An important target Mycobacterium tuberculosis infection. 3rd ScienceOne Conference on Drug Discovery and Development (SCDDD), 21-23 January 2014, Dubai.
  32. Yogeeswari, P.,  Patrisha J.T., Sriram, D., Structure-based drug design utilizing multiple crystal structures to design anti-viral agents, 3rd ScienceOne Conference on Drug Discovery and Development (SCDDD), 21-23 January 2014, Dubai.
  33. Mishra R.K., Matharasala G., Srivastav G., Singhal S.M., Sriram, D., Yogeeswari, P., Evaluation of antinociceptive properties of novel Rho Kinase inhibitors using animal models of neuropathic pain, 46th Annual Congress of the Indian Pharmacological Society IPSCON-2013, 16-18th December 2013, Bangalore, India.
  34. Matharasala G., Mishra R.K., Srivastav G., Singhal S.M., Sriram, D., Yogeeswari, P., Novel semicarbazone derivatives effective against Diabetic peripheral neuropathy, 46th Annual Congress of the Indian Pharmacological Society IPSCON-2013, 16-18th December 2013, Bangalore, India.
  35. Saketh, S.D., Reshma, A., Srikant, V., Sriram, D., Yogeeswari, P., BIA-6: A novel AKT inhibitor with potent activity in lung cancer, 15th World Conference on Lung Cancer, 27-30 October 2013, Sydney, Australia. 
  36. Madhu Babu, B., D. Sriram, P. YogeeswariTargeting microglial cathspsin S to treat neuropathic pain: Drug design and biological evaluation, 8th Congress of the European Federation of IASP Chapters- Pain in Europe VIII, 9-12 October 2013, Florence, Italy. 
  37. P. YogeeswariR.K. Mishra, A. Semwal, D. Sriram,  Evaluation of antinociceptive properties of novel curcumin derivatives using animal models of neuropathic pain, 5th ASEAPS (Association of South-East Asian Pain Societies Conference), Pain: The Unseen Disease, 2nd-5th May 2013, Singapore.
  38. J. T. Patrisha, D. Sriram, P. YogeeswariDiscovery of novel small molecule inhibitors of Human immunodeficiency virus (HIV) protease: Pharmacophore modeling, 3D QSAR studies and High-throughput screening, 2nd UK-India MedChem Congress, 22-23 March 2013, Hyderabad.
  39. B. K. Andrews, V.U. Jean Kumar, J. Renuka, P. Yogeeswari, D. Sriram, Discovery of novel benzimidazole class of antibacterial agents targeting the ATPase domains of DNA gyrase, 2nd UK-India MedChem Congress, 22-23 March 2013, Hyderabad.
  40. A.T. Dharmaraja, A. Mallika, D. Sriram, P. Yogeeswari, H. Chakrapani, Small molecule reactive oxygen species generator as antimycobacterial agents, 2nd UK-India MedChem Congress, 22-23 March 2013, Hyderabad.
  41. M. Siddharth Sai, V.U. Jean Kumar, A. Reshma, P. Yogeeswari, D. Sriram, In-Silico design, Synthesis and in-vitro screening of novel inhibitors of Chorismate mutase enzyme involved in Shikimate pathway of Mycobacterium tuberculosis, 2nd UK-India MedChem Congress, 22-23 March 2013, Hyderabad.
  42. P. Ganesh, V.U. Jean Kumar, P. Sridevi, P. YogeeswariD. Sriram, Development of novel substituted benzoxazolinone derivatives as potential antitubercular agents, 2nd UK-India MedChem Congress, 22-23 March 2013, Hyderabad.
  43. M. Brahmam, J. Renuka, V.U. Jean Kumar, P. YogeeswariD. Sriram, In-Silico discovery of novel phenylenediamine class of antibacterials as potential DNA gyrase inhibitors, 2nd UK-India MedChem Congress, 22-23 March 2013, Hyderabad.
  44. P. Santosh, V.U. Jean Kumar, A. Reshma, D. Sriram, P. YogeeswariDevelopment of carvacrol derivatives as potential inhibitors of MTB chorismate mutase, 2nd UK-India MedChem Congress, 22-23 March 2013, Hyderabad.
  45. S. Sahithi, J. Renuka, P. Yogeeswari, D. Sriram, In-Silico Design and in-vitro assay of inhibitors of pathogenic Staphylcoccus aureus DNA gyrase, 5th International Symposium of Drug development for Orphan/Neglected Diseases, 26-28 February 2013, Lucknow.
  46. P. Santosh, V.U. Jean Kumar, S. Saxena, P. Yogeeswari, D. Sriram, In-Silico Design and Synthesis of Novel Nitrothiazole derivatives as potential inhibitors of MTB CysK1, 5th International Symposium of Drug development for Orphan/Neglected Diseases, 26-28 February 2013, Lucknow.
  47. A.Seal, P. Yogeeswari, D. Sriram, D.J. Wild, OSDD Consortium, 3D Virtual Screening of PknB inhibitors using data fusion methods, 1st Official Conference of the International Chemical Biology Society, 4-5 October, 2014CambridgeMA, USA
  48. P. Yogeeswari, A.S.K. Reddy, J.V. Ragavendran, Arvind Semwal, Ram Kumar Mishra, D. Sriram, Spironucleus linked GABA analogues as potential antiepileptic agents acting through GABA mediation and inhibiting nitric oxide and free radicals,  10th European Congress on Epileptology30th Septemeber -4th October 2012, London, United Kingdom. 
  49. Ram Kumar Mishra, Reshma Chowdary,  D. Sriram,  P. YogeeswariDesign of Novel Rho Kinase Inhibitors for the treatment of Diabetic Complications  using Energy-based Pharmacophore Modelling, In-silico screening and Docking studies,  3rd World Congress on Diabetes & Metabolism,24-26 Septemeber 2012, Hyderabad, India.  
  50. P. Sripriya, M. Soumya, Reshma Alokam, P. Susruta,  D. Sriram,  P. YogeeswariStructure Guided Design of Inhibitors for SH3 domain of p47phox subunit of NADPH Oxidase 2 implicated in various human disorders,  3rd World Congress on Diabetes & Metabolism,24-26 Septemeber 2012, Hyderabad, India.  
  51. M. Saketh,  Ram Kumar Mishra, D. Sriram,  P. Yogeeswari Design of Novel Protein Kinase Inhibitors for the treatment of Painful Diabetic Neuropathy using  Energy-based Pharmacophore Modelling and Docking studies,  3rd World Congress on Diabetes & Metabolism,24-26 Septemeber 2012, Hyderabad, India. 
  52. A. Mallika, Shubmitha Bhatnagar, A. Ravi, V.U. Jean Kumar, T.H. Manjashetty,   P. Yogeeswari,  D. Sriram, Novel acridinone derivatives: Design, synthesis, SIRT1 enzyme and tumour cell growth inhibition studies,  3rd World Congress on Biotechnology,13-15 Septemeber 2012, Hyderabad, India.  
  53. Reshma Alokam, Jean Kumar,  D. Sriram,  P. YogeeswariIdentification of novel inhibitors of Chorismate mutase enzyme involved in Shikimic pathway of Mycobacterium tuberculosis: Design and In-vitro screening, 3rd World Congress on Biotechnology,13-15 Septemeber 2012, Hyderabad, India.  
  54. P. Venkat Koushik,  P. Yogeeswari,  D. Sriram, Designing Small Molecule Inhibitors of NMPRTase as Anticancer leads using in silico approach, 3rd World Congress on Biotechnology,13-15 Septemeber 2012, Hyderabad, India. 
  55. J.T. Patrisha, K. Sridevi, K. Shruti,  D. Sriram,  P. YogeeswariDiscovery of New Small Molecule Inhibitors of Hepatitis C Virus RNA-dependent RNA polymerase: Pharmacophore modelling, 3D-QSAR studies and High-throughput screening,  3rd World Congress on Biotechnology,13-15 Septemeber 2012, Hyderabad, India.  
  56. Madhu Babu, B., Madhuri Chandra, D. Sriram,  P. YogeeswariDiscovery of New Microglial Cathepsin S Inhibitors for the Treatment of Neuropathic Pain: Pharmacophore modelling, 3D-QSAR and High-throughput screening, 3rd World Congress on Biotechnology,13-15 Septemeber 2012, Hyderabad, India. 
  57. Devi, P.B., Mallika A.,  P. Yogeeswari, D. Sriram, Development of Pantothenate Synthetase Inhibitors for Mycobacterium Tuberculosis Infection: Design and Enzyme Inhibition,  3rd World Congress on Biotechnology,13-15 Septemeber 2012, Hyderabad, India.  
  58. Jean Kumar V.U, Manoj C., Vijay Soni, Patrisha J.T., Mallika A., Yogeeswari P., Nandicoori, V.K., Sriram D., Discovery of novel Mycobacterium tuberculosis GlmU inbibitors, 16th Annual Conference of the Swedish Structural Biology Network, 15-18 June 2012, Talberg, Sweden.
  59. Omer Poyraz, Robert Schnell, Jean Kumar V.U., Yogeeswari P., Sriram D., Gunter Schneider, Discovery of inhibitors targeting the Mycobacterium tuberculosis O-acetylserine sulfhydrylase (OASS) CysK1 as potential agents against mycobacterial latency. 16th Annual Conference of the Swedish Structural Biology Network, 15-18 June 2012, Talberg, Sweden.
  60. P. Ravichand, Ramakrishna Vadrevu, P. Yogeeswari, D. Sriram, Structure-based Pharmacophore Modeling and Virtual screening of β-secretase Inhibitors, International Conference on Advances in Biological Sciences, 15-17 March 2012, Kannur, Kerala, India. 
  61. Monika Sharma, Arvind Semwal, V. Deekshith, D. Sriram, P. Yogeeswari, Discovery of newer triazolo[3,4-b]thiadiazoles for the treatment of neuropathic pain: Pharmacophoric hybrid approach for multifunctional lead development, 4th International Conference on Drug Discovery & Therapy, 12-15 February  2012, Dubai, UAE.
  62. A. Ravi Kiran, D. Sriram, P. Yogeeswari, Prediction of bioactivity and toxicity of BITS Database compounds using empirical and focused scoring techniques,  63rd Indian Pharmaceutical Congress 2011, 19-21 December 2011, Bangalore, India.(WON THE BEST PAPER IN PODIUM SECTION)
  63. A. Monika, A.V. Ramani, V.U. Jean Kumar, H.M. Thimmappa, P. Yogeeswari, D. Sriram, One pot synthesis of novel substituted 1,3-thiazinylisonicotinamides, in-vitro evaluation and pre-pharmacokinetic profile studies for the treatment of tuberculosis, 63rd Indian Pharmaceutical Congress 2011, 19-21 December 2011, Bangalore, India. (WON THE SECOND BEST PAPER AWARD IN POSTER SECTION)   
  64. M. Siddarth Sai, A. Mallika, V.U. Jean Kumar, P. Yogeeswari, D. Sriram, In-silico design and synthesis of small molecule inhibitors of human SIRT1, 63rd Indian Pharmaceutical Congress 2011, 19-21 December 2011, Bangalore, India. 
  65. V. Mahesh Kumar, Sunil Kumar Sharma, V.U. Jean Kumar, P. Yogeeswari, D. Sriram, Design, Synthesis and in-vitro evaluation of novel imidazo-quinaxolone derivatives as potential anti-tubercular drugs, 63rd Indian Pharmaceutical Congress 2011, 19-21 December 2011, Bangalore, India.
  66. Sunil Kumar Sharma, V. Mahesh Kumar, V.U. Jean Kumar, P. Yogeeswari, D. Sriram, Design, Synthesis and in-vitro evaluation of novel 4-aminopiperido-thiazole derivatives as potential antitubercular agents, 63rd Indian Pharmaceutical Congress 2011, 19-21 December 2011, Bangalore, India.  
  67. Yukti Singh, Monika Sharma, D. Sriram, P. Yogeeswari, Neurotoxicological evaluation of BITS candidate drugs in four animals models,  XXXXIVth Annual Conference of Indian Pharmacological Society, 19-21 December 2011, Manipal, India.
  68. V. Deekshith, Monika Sharma, D. Sriram, P. Yogeeswari, Evaluation of analgesic activity of new chemical entities in two rodent models of pain, XXXXIVth Annual Conference of Indian Pharmacological Society, 19-21 December 2011, Manipal, India.
  69. M. Gangadhar, Monika Sharma, D. Sriram, P. Yogeeswari, Preclinical evaluation of some novel heterocycles against postoperative pain, XXXXIVth Annual Conference of Indian Pharmacological Society, 19-21 December 2011, Manipal, India.
  70. Monika Sharma, M. Ganghadhar, Binita Kundu, Arvind Semwal, D. Sriram, P. Yogeeswari, Pharmacological profiling of triazolone derivatives as new leads for neuropathic pain treatment, XXXXIVth Annual Conference of Indian Pharmacological Society, 19-21 December 2011, Manipal, India.
  71. Siddarth Sai, M., Jean Kumar, P. Yogeeswari, D. Sriram, Design, synthesis and in-vitro evaluation of novel piperido-hydrazine derivatives as potential anti-tubercular agents, MedChem-2011 Conference on Anti-infective drug Discovery & Development, 28-29th October 2011, Indian Institute of Technology, Chennai, India.(WON THE BEST PAPER IN POSTER SECTION)  
  72. P. Yogeeswari, A.Sunil Kumar Reddy, Arvind Semwal, M. Arjun, D. Sriram, Multifunctional drug lead discovery for the treatment of neuropathic pain including trigeminal neuralgia and diabetic neuropathy: Combination of GABA receptor, cannabinoid receptor and nitric oxide as targets, 14th Asian Chemical Congress, 5-8 Septemeber 2011, Bangkok, Thailand.
  73. Jean Kumar, Thimmappa H.M., Pritesh Bhatt, Srividya M., P. Yogeeswari, D. Sriram, In-silico design and synthesis of novel 2-(1-aminocyclobutyl)-2-hydroxy acetic acid as potential inhibitors of Mycobacterium tuberculosis isocitrate lyase, RSC MedChem-2011, 25-26th February 2011, Indian Institute of Chemical Technology, Hyderabad, India.
  74. Thimmappa H.M., P. Yogeeswari, D. Sriram, Synthesis and evaluation of isonicotinoylpyrazolopiperidine derivatives for the treatment of tuberculosis, RSC MedChem-2011, 25-26th February 2011, Indian Institute of Chemical Technology, Hyderabad, India.
  75. Monika A., Thimmappa H.M., P. Yogeeswari, D. Sriram, Dicyclohexylcarbodiimide mediated one pot synthesis of novel substituted 1,3- thiazinylisonicotinamides and evaluation for the treatment of tuberculosis, RSC MedChem-2011, 25-26th February 2011, Indian Institute of Chemical Technology, Hyderabad, India.
  76. Mallika A., Ravikiran A., P. Yogeeswari, D. Sriram, Development of homology model and docking studies of Mycobacterium tuberculosis sirtuin protein (Rv1151c), RSC MedChem-2011, 25-26th February 2011, Indian Institute of Chemical Technology, Hyderabad, India.
  77. P. Yogeeswari, A. Sunil Kumar Reddy, A. Semwal, D. Sriram, Novel role of GABAergic anticonvulsant compounds in alleivating neuropathic pain in two animal models, 43rd Annual Conference of Indian Pharmacological Society & International Conference on Pharmacology & Translational Research & ICMR Centenary Year Celebrations, 13-16th December 2010, NIN, Hyderabad, India.
  78. Monika Sharma, A. Sunil Kumar Reddy, A. Semwal, D. Sriram, P. Yogeeswari, Effectiveness of Newer Lipophilic GABA analogues against epilepsy, 43rd Annual Conference of Indian Pharmacological Society & International Conference on Pharmacology & Translational Research & ICMR Centenary Year Celebrations, 13-16th December 2010, NIN, Hyderabad, India.
  79. P. Yogeeswari, M. Arjun, A. Semwal, R. Thirumurugan, D. Sriram, Novel role of GABAergic Anticonvulsant Compounds in allievating neuropathic pain like behaviour in rodent models of incisional pain by inhibiting nitric oxide, 24th Annual Conference of Indian Society of Pain, 6-8 February 2009, Hyderabad, India.
  80.  P. Senthil Kumar, M. Dinakaran, P. Yogeeswari, D. Sriram, A. China, V. Nagaraja, Synthesis and antimycobacterial activities of novel 6-nitoquinolones-3-carboxylic acid, 59 th Indian Pharmaceutical Congress,20-23rd December 2007, Varanasi, India.
  81.  A. Sunil Kumar Reddy,  D. Sriram, V. Ranganadh, P. Yogeeswari, Synthesis  of newer N-spiro substituted GABA derivatives as anticonvulsants, 59th Indian Pharmaceutical Congress,20-23rd December 2007, Varanasi, India.
  82.  Meena K. Purohit, Niloufer M, P. Senthil Kumar, P. Yogeeswari, D. Sriram, A facile microwave-assisted synthesis of novel 3,5-dinitrosalicylamides and their antimycobacterial activity, 59th Indian Pharmaceutical Congress,20-23rd December 2007, Varanasi, India.
  83. Niloufer M, Meena K. Purohit, P. Senthil Kumar, J. Vaigunda Ragavendran, M. Arjun, D. Sriram, P. Yogeeswari,  Synthesis, antiallodynic and antihyperalgesic activities of 5-(4-nitrophenyl)furoic 2-acid hydrazones in two in-vivo models of neuropathic pain, 59th Indian Pharmaceutical Congress,20-23rd December 2007, Varanasi, India.
  84. D. Sriram, M. Dinakaran, R.V. Devakaram, P. Yogeeswari, Synthesis and antimalarial activity of aromatic amino analogues of artemisinin, 58th Indian Pharmaceutical Congress, 1-3rd December 2006, Mumbai, India.
  85. A.S.K. Reddy, Y. Nageswari, S.K. Patel, D. Sriram, P. Yogeeswari, Newer GABA analogs as CNS agents: Synthetic integration of GABA in 1,2,4-triazol-2H-3-one, 58th Indian Pharmaceutical Congress, 1-3rd December 2006, Mumbai, India.
  86. P. Senthil kumar, M. Dinakaran, P. Yogeeswari, D. Sriram, Synthesis and in vitro antimycobacterial activity of some novel fluoroquinolones, 58th Indian Pharmaceutical Congress, 1-3rd December 2006, Mumbai, India.
  87. J.V. Ragavendran, I. Vikram Reddy, P. Yogeeswari, D. Sriram, Synthesis of 4-{[(3Z)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]amino}-N-substituted phenyl) butanamides possessing antiallodynic and antihyperalgersic activities in two rat models of neuropathic pain, 3rd International Symposium on Current Trends In Drug Discovery Research CTDDR - 2007, 17 - 21st February 2007, Chandigarh, India.
  88. D. Banerjee, T.R. Bal, P. Yogeeswari, D. Sriram, L. Sebastin, A. Desai, S.N. Madhusudhana, V. Ravi, Isatin derivatives inhibit Japanese encephalitis virus entry and replication in-vitro, 3rd International Symposium on Current Trends In Drug Discovery Research CTDDR - 2007, 17 - 21st February 2007, Chandigarh, India.
  89. P. Senthil Kumar, M. Dinakaran, P. Yogeeswari, D. Sriram, Synthesis and antitubercular activities of 1-(cyclopropyl/t-butyl/4-fluorophenyl)-1,4-dihydro-6-nitro-4-oxo-7-(substituted secondary amines)-1,8-naphthyridine-3-carboxylic acid, 3rd International Symposium on Current Trends In Drug Discovery Research CTDDR - 2007, 17 - 21st February 2007, Chandigarh, India.
  90. A.S.K. Reddy,  J.V. Ragavendran, P. Yogeeswari, D. Sriram, Pharmacological screening of candidate anticonvulsants in the animal model of febrile seizures, 3rd International Symposium on Current Trends In Drug Discovery Research CTDDR - 2007, 17 - 21st February 2007, Chandigarh, India.
  91. K.N. Purna, P. Dhakla, P. Senthil Kumar, P. Yogeeswari, D. Sriram, 5-Nitro-2-furaldehyde thiosemicarbazones: Synthesis and in-vitro antimycobacterial activities, 3rd International Symposium on Current Trends In Drug Discovery Research CTDDR - 2007, 17 - 21st February 2007, Chandigarh, India.
  92. M. Dinakaran, C. Yogesh, P. Yogeeswari, D. Sriram, Synthesis of various 7-substituted-1-t-butyl-1,4-dihydro-8-methyl-6-nitro-4-oxo quiniline-3-carboxylic acid, 3rd International Symposium on Current Trends In Drug Discovery Research CTDDR - 2007, 17 - 21st February 2007, Chandigarh, India.
  93. P. Yogeeswari, Synthesis of 4-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)N-(substitutedphenyl)butanamides possessing antiallodynic and antihyperalgesic activities in two rat models of neuropathic pain, 11th APTI National Convention, 1-3 September, 2006, Bangalore, India (WON THE BEST PAPER IN PODIUM SECTION)
  94. P. Yogeeswari, R. Kavya, V. Reddy, D. Sriram, Newer approaches in the design of Anticonvulsants effective in hyperthermia-induced febrile seizures, 6th Asian & Oceanian Epilepsy Congress, 16-19th Novemeber 2006, Kuala Lumpur, Malaysia.
  95. D. Sriram, S. Mehta, Discovery of lesser neurotoxic and effective anticonvulsant agents active in four animal models of seizure, 6th Asian & Oceanian Epilepsy Congress, 16-19th Novemeber 2006, Kuala Lumpur, Malaysia.
  96. V. Ragavendran, R. Kumar, P. Yogeeswari, Design of GABA uptake inhibitors: Synthesis and anticonvulsant properties, 6th Asian & Oceanian Epilepsy Congress, 16-19th Novemeber 2006, Kuala Lumpur, Malaysia.
  97. D. Sriram, M. Dinakaran, R.V. Devakaram, P. Yogeeswari, Synthesis and antimalarial activity of aromatic amino analogues of artemisinin, 58th Indian Pharmaceutical Congress, 1-3rd December 2006, Mumbai, India.
  98. A.S.K. Reddy, Y. Nageswari, S.K. Patel, D. Sriram, P. Yogeeswari, Newer GABA analogs as CNS agents: Synthetic integration of GABA in 1,2,4-triazol-2H-3-one, 58th Indian Pharmaceutical Congress, 1-3rd December 2006, Mumbai, India.
  99. P. Senthil kumar, M. Dinakaran, P. Yogeeswari, D. Sriram, Synthesis and in vitro antimycobacterial activity of some novel fluoroquinolones, 58th Indian Pharmaceutical Congress, 1-3rd December 2006, Mumbai, India.
  100. Rohit Nelli, P. Senthil Kumar, P. Yogeeswari, D. Sriram, Microwave-assisted synthesis of some novel 2-[3-(4-bromo-2-fluorobenzyl)-4-oxo-3,4-dihydrophthalazin-1-yl]-N-substituted amides, National Symposium on Challenges in Drug Discovery Research: Networking Opportunities between Academia & Industries, 7-8th April, 2006, Pilani, India.
  101. V. Ranganadh, P. Roheeth Kumar, M. Mallika, P. Yogeeswari, D. Sriram, Synthesis of copper complexes of thiosemicarbazones as antitumour agents, National Symposium on Challenges in Drug Discovery Research: Networking Opportunities between Academia & Industries, 7-8th April, 2006, Pilani, India.
  102. J.V. Ragavendran, R. Kavya, S.K. Patel, D. Sriram, P. Yogeeswari, Design and synthesis of 4-[(2-oxo-1,2-dihydro-3H-indol-3-ylidene)amino] butanmaides as 4-aminobutyric acid (GABA) mimetics,  National Symposium on Challenges in Drug Discovery Research: Networking Opportunities between Academia & Industries, 7-8th April, 2006, Pilani, India.
  103. Y. Nageswari, P. Sahithya, J.V. Ragavendran, D. Sriram, P. Yogeeswari, Synthesis and anticonvulsant evaluation of 2,6-dimethylphenylaminoacetylamino butanamides, National Symposium on Challenges in Drug Discovery Research: Networking Opportunities between Academia & Industries, 7-8th April, 2006, Pilani, India.
  104. M. Mallika, P. Yogeeswari, D. Sriram, Design and synthesis of gold (III) and platinum (III) complexes of aryl-substituted semicarbazones as antitumour agents, National Symposium on Challenges in Drug Discovery Research: Networking Opportunities between Academia & Industries, 7-8th April, 2006, Pilani, India.
  105. Jatinder Kaur, Simarjeet Kaur, P. Yogeeswari, D. Sriram, Pharmacophore modeling of COX-2 inhibitors, National Symposium on Challenges in Drug Discovery Research: Networking Opportunities between Academia & Industries, 7-8th April, 2006, Pilani, India.
  106.  Debjani Banerjee, M. Dinakaran, P. Senthil Kumar, R.V. Devakaram, P. Yogeeswari, D. Sriram, Synthesis and Antibacterial evaluation of Phenothiazine derivatives, National Symposium on Challenges in Drug Discovery Research: Networking Opportunities between Academia & Industries, 7-8th April, 2006, Pilani, India.
  107. Bhargava, P. Senthil Kumar, P. Yogeeswari, D. Sriram, Synthesis of certain 7-substituted fluoroquinolones, National Symposium on Challenges in Drug Discovery Research: Networking Opportunities between Academia & Industries, 7-8th April, 2006, Pilani, India.
  108. Y. Nageswari, J.V. Ragavendran, D. Sriram, P. Yogeeswari, Design and Synthesis of 4-(1,3-Dioxoisoindolin-2-yl)butane hydrazones as anticonvulsant pharmacophoric hybrids, 2nd International Symposium on Drug Discovery & Process Research, 10-12th Feb, 2006, Belgaum, India.
  109. J.V. Ragavendran, S.K. Patel, D. Sriram, P. Yogeeswari, Design and Synthesis of Newer amino derivatives of 4-aminobutyric acid as anticonvulsants, 2nd International Symposium on Drug Discovery & Process Research, 10-12th Feb, 2006, Belgaum, India.
  110. R. Kavya, J.V. Ragavendran, D. Sriram, P. Yogeeswari, Pharmacological evaluation of the analgesic efficacy of candidate anticonvulsant compounds in neuropathic pain models, 2nd International Symposium on Drug Discovery & Process Research, 10-12th Feb, 2006, Belgaum, India.
  111. M. Shalini, J.V. Ragavendran, P.R. Kumar, D. Sriram, P. Yogeeswari, Quantum mechanical modeling of aryl semicarbazones as anticonvulsants, 2nd International Symposium on Drug Discovery & Process Research, 10-12th Feb, 2006, Belgaum, India.
  112. P. Yogeeswari, J.V. Ragavendran, Animal models of seizures, '6th EMBL International Predoc Symposium "Animal Models - Tips and Tricks from Nature", 11-13th May 2005, Rome, Italy.
  113. P. Yogeeswari, Drug design based on Molecular hybridization and integration, International Symposium on Recent Advances in drug design and delivery systems, 26-27th Feb, 2005, BITS, Pilani, India.
  114. D. Sriram, T.R. Bal, P. Yogeeswari, Aminopyrimidinimino isatin analogues: Design and synthesis of novel non-nucleoside HIV-1 reverse transcriptase inhibitors with broad spectrum Antimicrobial properties, National Symposium on Futiritic trends in Pharmacotherapeutics and formulation development, Banaras Hindu University, Varanasi, March 4-5th, 2005.
  115. P. Yogeeswari, D. Sriram, P. Roheeth Kumar, Development of Anticonvulsant leads by integrating structure-based drug design and database screening, National Symposium on Futiritic trends in Pharmacotherapeutics and formulation development, Banaras Hindu University, Varanasi, March 4-5th, 2005.
  116. R.V. Devakaram, N.S. Myneedu, P. Yogeeswari, D. Sriram, Microwave-assisted synthesis and anti-YFV activity of 2,3-diaryl-1,3-thiazolidin-4-ones, International Symposium on Recent Advances in drug design and delivery systems, 26-27th Feb, 2005, BITS, Pilani, India.
  117. P.R. kumar, G.A. Nilkanth, P. Yogeeswari, Rational approach for the design of a central nervous system active chemical library, International Symposium on Recent Advances in drug design and delivery systems, 26-27th Feb 2005, BITS, Pilani, India.
  118. K. Srikanth, V. Ranganadh, D.R.K. Vyas, B. Murali Krishna, P. Yogeeswari, D. Sriram, Design of anticonvulsant drug database, International Symposium on Recent Advances in drug design and delivery systems, 26-27th Feb, 2005, BITS, Pilani, India.
  119. V.N.R. Pavan Kumar, P. Yogeeswari, D. Sriram, T.R. Bal, QSAR studies on Non-Nucleoside reverse transcriptase inhibitors belonging to phenylethylthiazolylthiourea, International Symposium on Recent Advances in drug design and delivery systems, 26-27th Feb, 2005, BITS, Pilani, India.
  120. P. Kudyar, P. Yogeeswari, M. Shalini, D. Sriram, Synthesis of 2,5-dimethylphenyl substituted semicarbazones as anticonvulsants, International Symposium on Recent Advances in drug design and delivery systems, 26-27th Feb, 2005, BITS, Pilani, India.
  121. K. Purna Nagasree, P. Yogeeswari, D. Sriram, Newer isonicotinoyl hydrazones: Synthesis and in-vitro antimycobacterial activity, International Symposium on Recent Advances in drug design and delivery systems, 26-27th Feb, 2005, BITS, Pilani, India.
  122. J. V. Ragavendran, P. Yogeeswari, R. Thirumurugan, D. Sriram, In-vitro and ex-vivo enzyme inhibition studies on some BITS anticonvulsant compounds, International Symposium on Recent Advances in drug design and delivery systems, 26-27th Feb, 2005, BITS, Pilani, India.
  123. M. Shalini, P. Yogeeswari, D. Sriram, J. P. Stables, Synthesis of some 4,5-(substituted diphenyl)-2H-1,2,4-triazole-3(4H)-one derivatives and their anticonvulsant properties, International Symposium on Recent Advances in drug design and delivery systems, 26-27th Feb, 2005, BITS, Pilani, India.
  124. R. Kavya, S. Tiwari, P. Yogeeswari, D. Sriram, Synthesis and in-vitro cytotoxicity evaluation of gatifloxacin Mannich bases, International Symposium on Recent Advances in drug design and delivery systems, 26-27th Feb, 2005, BITS, Pilani, India.
  125. T.R. Bal, P. Yogeeswari, D. Sriram, Aminopyrimidinimino isatin analogues: Design and synthesis of novel non-nucleoside HIV-1 reverse transcriptase inhibitors with broad spectrum Antimicrobial properties, International Symposium on Recent Advances in drug design and delivery systems, 26-27th Feb, 2005, BITS, Pilani, India.
  126. R. Kavya, R. Thirumurugan, D. Sriram, P. Yogeeswari; “Pharmacological Evaluation of aryl(heteroaryl) semi(thio)carbazones for CNS activity” 55th Indian Pharmaceutical congress, Chennai, December 19-21, 2003.
  127. J. Vaigunda Ragavendran, R. Thirumurugan, I. Sridharan, D. Sriram, P. Yogeeswari; “4-amino butyrate amino transferase (GABA-T) inhibition as a possible mechanism of some novel anticonvulsant aryl semicarbazones”, 55th Indian Pharmaceutical Congress, Chennai, December, 19-21, 2003.
  128. R. Thirumurugan, D. Sriram, P. Yogeeswari; “Design and synthesis of novel aryl semicarbazone derivatives as anticonvulsants with GABA and glycine mediated mechanism”, International symposium on drug discovery and process research, Shivaji University, Kolhapur, January 23-25, 2003.
  129. T. R. Bal, D. Sriram, P. Yogeeswari, Non-nucleoside reverse transcriptase inhibitors for the treatment of AIDS, International symposium on Emerging trends in Genomics and Proteomics education and research, BITS, Pilani, Jan 12-13th, 2003.
  130. K. Jyothi Mallika, R. Thirumurugan, N.S. Chakravarthy, P. Yogeeswari, D. Sriram; “Tetrahydro-2H-1,3,5-thiadiazine-5-(4-Pyridyl carboxamide)-2-thione derivatives as prodrugs for isoniazid : synthesis and Antituberculous Activity”, 54th Indian Pharmaceutical Congress, Pune, December, 13-15, 2002.
  131. I. Sridharan, B. Archana, R. Thirumurugan, P. Yogeeswari, D. Sriram; “γ-Aminobutyric acid (GABA) level studies on novel anticonvulsant compounds in rat brain tissue preparation”, 54th Indian Pharmaceutical Congress, Pune, December 13-15, 2002.

 

 

 

International Visits

 

 
  1. Dubai, UAE, BITS-Pilani, Dubai campus conference on Biotechnological Innovations in Food and Healthcare, January 2019.
  2. Kuala Lumpur, Malaysia - Entrepreneurship summit, December 2018.
  3. Dubai, UAE- Speaker at 18th International Conference on Medicinal and Pharmaceutical Chemistry held in October 2018
  4. Irvine, California, USA- Visited UCI Technology Business Centre for a Business Plan Competition in June 2017.
  5. Barcelona, Spain- Speaker at the 8th Annual Congress of Neurotalk-2017 in May 2017.
  6. Whistler, British Columbia, Canada-Presented research paper at the Keystone Symposia on Cancer Immunology and Immunotherapy in March 2017
  7. Lille and Paris, France- Research exchange visit to Pasteur Institute at Lille and Paris in April 2015.
  8. Buenos Aires, Argentina- To receive IASP2014 award for excellence in Pain research among the developing country scientists in October 2014.
  9. Dubai, UAE- To present a research paper on Antiviral drug design in the 3rd ScienceOne Conference on Drug Discovery & Development in Jan 2014.
  10. Kiev, Ukraine- Visited Bogomoletz Institute of Physiology and Institute of Organic Chemistry for a collaborative research visit in May 2013.
  11. Singapore- Presented a research paper on Neuropathic pain research in the 5th Association of South-East Asian Pain Societies Conference in May 2013.
  12. Durban, South Africa- Visited KwaZuluNatal University for collaborative research visit and K-RITH as invited speaker in February 2013.
  13. Belem, Brasil- Visited Federal University of Para on a collaborative research visit during September 2012.
  14. Stockholm, Sweden- Visited Karolinska Institute on a collaborative project visit during May 2012.
  15. Stockholm, Sweden- Visited Karolinska Institute on a collaborative project visit during October-November 2010.

 

International student exchanges and training

 

     1. Mr. Ahik Seal, Ph.D. student of Indiana University, Bloomington, USA was offered training in CADD lab for 3 months from June 2012-August 2012 under IUSSTF RISE program under the supervision of Prof. P. Yogeeswari and Prof. D. Sriram.
     2. Mr. Edikarlos, Ph.D. student of Federal University of Para, Brazil spent 2 months for research project training in Drug Synthesis during November 2012-December 2012 sponsored by IBSA project.
     3. Ms. Glacia Nascimoto, Ph.D. student of  Federal University of Para, Brazil spent 2 months for research project training in High-throughput cell assays during November 2012-December 2012 sponsored by IBSA project.
     4. Mr. Guilherme Peterson, Ph.D. student of  Instituto Nacional de Ciência e Tecnologia em Tuberculose, Brazil was on exchange fellowship under Science Without Borders for 6 months at our CADD and Drug screening lab from October 2013 till April 2014.
     5. Mr. Bomba Tatsinkou Francis Desire, Ph.D. student of University of Dschang, Cameroon was on exchange fellowship supported by NAM S&T Centre under the research training fellowship for developing countries scientist in our Neuropathic pain research lab from March 2014 till September 2014.
      6. Ms. Kenia Pissinate, Post Doc of Instituto Nacional de Ciencia e Technologia em Tuberculose, Brazil was on exchange fellowship under Science Without Borders for 2 months at our CADD and Drug synthesis labs under the supervision of Prof. Yogeeswari and Prof. Sriram from 1st Feb 2015 till 31st March 2015.
7. Ms. Mediesse Kengne Francine, Research Assistant, The Biotechnology Centre of Nkolbisson, University of Yaounde I Messa is being approved on  exchange fellowship supported by NAM S&T Centre under the research training fellowship for developing countries scientist in our Research lab from May 2015 till October 2015.

 

 

 

Research Students
B.Pharm Projects guided: 150
B.Pharm thesis guided: 9
B.E. projects guided: 10
M.Pharm projects guided: 55
M.Pharm dissertation guided:7

Ph.D. Students Details:
Completed: 21
1. Dr. Shalini Mehta on “SYNTHESIS AND STRUCTURE-ACTIVITY RELATIONSHIP OF NEW ARYL AND HETEROARYL SEMICARBAZONES AS ANTICONVULSANTS”- Completed in 2007. (Current position: Works at FDA & F. Hoffmann La Roche AG, USA)
2. Dr. J.Vaigunda Raghavendran on "DESIGN OF GABA ANALOGUES AS ANTICONVULSANTS - SYNTHESIS & NEUROPHARMACOLOGY"- Completed in 2008. (Current position: Scientific Medical Writer, Ogilvy CommonHealth Worldwide, Montreal, Canada)
3. Dr. A.S.K. Reddy on "SYNTHESIS AND NEUROPHARMACOLOGY OF 4-AMINOBUTYRIC ACID ANALOGUES"- Completed in 2009. (Current position: Scientist at Aurobindo Pharma, Hyderabad, India)
4. Dr. Arvind Semwal on "PHARMACOLOGICAL INTERVENTIONS TO IDENTIFY POTENTIAL DRUG CANDIDATES FOR THE TREATMENT OF NEUROPATHIC PAIN"- Completed in 2012 (Current position: senior Manager, Medical Writing, Parexel International, Hyderabad, India)
5. Dr. Pritesh Bhat on “DESIGN OF VARIOUS NEW ENZYME INHIBITORS AS ANTIMYCOBACTERIAL AGENTS USING IN-SILICO HIGH-THROUGHPUT SCREENING"- Completed in 2013. (Current position: Senior Applications Scientist at Schrodinger, Bangalore, India)
6. Dr. Monika Sharma on "DESIGN AND SYNTHESIS OF MULTIFUNCTIONAL LEADS FOR THE TREATMENT OF NEUROPATHIC PAIN"- Completed in 2013. (Current position: Postdoctoral Fellow, Nanyang Technical Universty (NTU), Singapore)
7. Dr. J.T. Patrisha on "PHARMACOPHORE MODELING AND 3D QSAR COMBINED WITH VIRTUAL SCREENING TO IDENTIFY NOVEL INHIBITORS OF PROTEIN TARGETS OF INFECTIOUS DISEASES"-Completed in 2015. (Current position: Entrepreneur, Trinity Groups, India)
8. Dr. Madhu Babu B on "DESIGN, SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF NOVEL CATHEPSIN S INHIBITORS"- Completed in 2015. (Current position: Entrepreneur- Started a Diagnostic Centre)
9. Dr. Saketh Sriram on "STRUCTURE-BASED DESIGN AND SYNTHESIS OF NOVEL AKT INHIBITORS FOR PRECLINICAL EVALUATION IN LUNG CANCER CELL LINES"-Completed in 2015.(Current position: PostDoc, Penn State College of Medicine, Hershey, PA)
10. Dr. P. Brindha Devi on "DEVELOPMENT OF NOVEL PANTOTHENATE SYNTHETASE AND LYSINE AMINOTRANSFERASE INHIBITORS AGAINST ACTIVE AND DORMANT TUBERCULOSIS"- Completed in 2015.(Current position: Assistant Professor, Department of Bio-Engineering, Vels Institute of Science, Technology and Advanced Studies, Chennai, India)
11. Dr. Ram Kumar Mishra on "DESIGN AND CHARACTERIZATION OF NOVEL PROTEIN KINASE INHIBITORS FOR THE TREATMENT OF NEURONAL COMPLICATIONS OF DIABETES"- Completed in 2015. (Current position: Project Analyst, ICON PLC, Bangalore, India)
12. Dr. Reshma Chowdhary on "DUAL INHIBITORS OF ROCK-I AND NOX2 TO ATTENUATE NEUROINFLAMMATION IN NEUROLOGICAL DISORDERS: HIGH THROUGHPUT VIRTUAL ND BIOLOGICAL SCREENING"- Completed in 2015. (Current position: Research Associate, Centre for DNA Fingerprinting and Diagnostics (CDFD), Hyderabad, India)
13. Dr. Venkat Koushik (CSIR SRF) on "TARGETING SIRT1 AND ITS PATHWAY FOR THERAPEUTIC INTERVENTION OF CANCER: DRUG DESIGN AND BIOLOGICAL EVALUATION"- Completed in March 2016 (Current position: Senior Product Manager, Merck Group Bangalore, India)
14. Dr. Brahmam Medapi (ICMR SRF) on DEVELOPMENT OF NOVEL QUINOLINE ANALOGUES AS MYCOBACTERIUM TUBERCULOSIS DNA GYRASE INHIBITORS- Completed in June 2016. (Current Position: Associate Scientist, GVKBio, Bangalore, India)
15. Dr. Priyanka S on "COMPUTATIONAL ANALYSES OF MYCOBACTERIUM TUBERCULOSIS ENZYME INHIBITORS: A STUDY INVOLVING FREE ENERGY PERTURBATION AND MOLECULAR DYNAMICS SIMULATIONS"-Completed in Dec 2016. (Current Position: Post Doctoral Scientist, University of Kentucky)
16. Dr. Srikant Racharla on DESIGN, SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF NOVEL ADENOSINE A2 MODULATORS FOR TREATMENT OF EPILEPSY AND PAIN- Completed in September 2016. (Current Position: Research Associate, Hospira, Pfizer company, Chennai)
17. Dr. Hasitha S Anantharaju (DST INSPIRE Fellow) on CATHEPSIN D, AN ASPARTATE PROTEASE AS A POTENT THERAPEUTIC OPTION FOR BREAST CANCER: DESIGN, SYNTHESIS AND BIOEVALUATION AGAINST TRIPLE POSITIVE AND TRIPLE NEGATIVE BREAST CANCERS- Completed in October 2017. (Current Position: Scientific Writer II, Novartis, Hyderabad, India)
18. Dr. M. Gangadhar on "MOLECULAR PHARMACOLOGICAL INVESTIGATIONS ON NEW CHEMICAL ENTITIES USEFUL IN THE TREATMENT OF NEUROPATHIC PAIN - Completed in Feb 2018 (Current Position: Senior Research Associate, GVK EXCELRA, Hyderabad)
19. Dr. Pushkar Kulkarni (ILS, Hyderabad) on "ZEBRA FISH MODELS FOR NEUROSCIENCE DRUG DISCOVERY -Completed in June 2018 (Current Position: Dr. Reddy's Institute of Life Sciences, University of Hyderabad campus, Hyderabad)
20. Mr. Shubham Diwedi (DBT JRF, BITS Scholar, ICMR SRF) on DEVELOPMENT, VALIDATION, AND EXPLORATION OF NOVEL DISEASE MODELS FOR AUTISM, Completed in December 2019 Current Position: Assistant Professor, University of Petroleum and Energy Studies, Uttarkhand )
21. Mr. Parameshwar Reddy (AMRI, Hyderabad) on SYNTHESIS OF NOVEL LEADS USEFUL FOR NEUROLOGICAL DISEASES, Completed in September 2021

Presently Guiding: 4
Ms. Purbali Chakraborty (ICMR SRF) on DRUG DISCOVERY FOR ORAL CANCER
Ms. Dipika Sahu on DRUG DISCOVERY FOR COLORECTAL CANCER
Ms. Deepika (ICMR JRF) on NEUROPHARMACOLOGICAL INTERVENTION FOR PAIN THERAPEUTICS
Mr. Madan (Almelo Industry) on DRUG SYNTHESIS FOR CANCER RESEARCH