Extramural and Intramural Projects (Completed as PI and co-PI between 2013-2025):

1. Science and Engineering Research Board (SERB) (2013-2016-Completed as PI): The Role of Hippo Signaling Pathway Components in Autophagy Regulation in Hepatocellular Carcinoma.
2. University Grants Commission (UGC) (2013-2015-Completed as PI): Identifying miRNA signatures associated with autophagy induced chemoresistance in hepatocellular carcinoma.
3. Department of Biotechnology (DBT) (2015-2019-Completed as PI): Mutant-p53 gain-of-function: its role in regulating long noncoding RNA (lncRNA) expression and associated chemo-resistance.
4. Science and Engineering Research Board (SERB) (2017-2020-Completed as co-PI): Evaluation of anti-tumor efficacy and pharmacokinetics of polymeric nanoparticle formulation targeted to cancer stem cells.
5. Department of Science and Technology (DST, Rajasthan) (2018-2021-Completed as co-PI): Activity targeted nano-formulations for co-delivery of a taxane and anti-oxidant molecule, alpha lipoic acid for treating breast cancer.
6. Science and Engineering Research Board (SERB) (2018-2022-Completed as PI): Understanding hyperglycemia induced alterations in non-coding RNA expression pattern and post–translational histone protein modifications contributing to drug resistance and progression of pancreatic cancer.
7. Indian Council of Medical Research (ICMR) (2019-22-Completed as co-PI): Studying the Efficacy of ADAM Inhibitors in Treating Diabetic Nephropathy.
8. Science and Engineering Research Board (SERB) (2019-22-Completed as co-PI): Analysis of mitochondrial dynamicity (fusion/fission and mitophagy) post drug exposure in human glioblastoma cells and understanding its correlation with drug resistance.
9. Indian Council of Medical Research (ICMR) (2019-23-Completed as co-PI): Repurposing of CNS accumulating drugs as autophagy modulators for potential treatment against glioblastoma: an in-silico, in-vitro and in-vivo study.
10. Life Sciences Research Board (LSRB, DRDO) (2019-2023-Completed as PI): High Altitude-Hypoxia Mediates Thrombosis in Soldiers; Modulation of Autophagy as A Strategy to Combat High Altitude-Hypoxia Induced Thrombosis.
11. Indian Council of Medical Research (ICMR) (2021-23-Completed as co-PI): An in silico and in vitro characterization of binding affinity and internalization potential of Indian SARS-CoV-2 spike protein variants with hACE-2 and identification of potential small molecules hindering the interaction.
12. BITS BioCyTiH Foundation (BioCyTIH) (2022-2024-Completed as PI): Identification of novel biomarkers in ovarian cancer and design of appropriate prognostic probes.
13. Science and Engineering Research Board (SERB) (2021-24-Completed as co-PI): Neuronal regulation of tumor cell migration- understanding the role of semaphorins in tumor cells undergoing EMT and subjected to differential flow dynamics.
14. Indian Council of Medical Research (ICMR) (2021-24-Completed as PI): Targeting chromatin modifiers- Jumonji Histone Demethylases in tumor cells surviving acute drug stress: an in vitro and in vivo study.
15. Indian Council of Medical Research (ICMR) (2021-24-Completed as co-PI): Development of novel Aggregation Induced Emission (AIE) Active iridium (III) based Near IR Emissive compounds and their encapsulation into pH sensitive nanoparticles for tumor targeting and photodynamic therapy.
16. Indian Council of Medical Research (ICMR) (2021-2024-Completed as co-PI): Exploring the role of 'Secretary Arm of Autophagy' in Glioblastoma therapy resistance: an in vitro and patient data based study.
17. Department of Biotechnology (DBT) (2021-24-Completed as co-PI): Rapid, low cost fluorescent AIE based detection of renal dysfunction from urine samples and fabrication of portable and real time device.
18. Cross-Disciplinary Research Framework (CDRF) (2022-2024- Intramural-Completed as PI) Exploring the efficacy of chemo-photodynamic combination therapy for skin cancer and design of nanocarriers for their side-specific delivery.