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Prof. Gaikwad Anil Bhanudas

Professor, Department of Pharmacy,
BITS Pilani, Pilani Campus

Pharmacology
Department of Pharmacy, Birla Institute of Technology & Science, Pilani- 333031, Rajasthan. India.

Lab Members

 

Post-Doctoral Fellows

S.No Name Project title Year started Funding
1 Dr. Vigneshwaran Pitchaimani Alternate day fasting resembles recurrent insulin-induced hypoglycemia model in rat April 2018 to March 2020 SERB-NPDF
2 Dr. Vivek Akhouri Interdisciplinary life science programme for advanced research and education in epigenetics and genome editing 29 August 2022 DBT-BUILDER

 

Ph.D. Students (Completed)

S.No Name Thesis title Completion year  Present status
1
Dr. Almesh Kadakol
(Supervisor) 
Role of angiotensin II on vascular epigenetics in the development of atherosclerosis and therapeutic intervention of esculetin under type 2 diabetic conditions associated with renal failure 23rd April 2018 Therapy Lead, MedTech & Lead MSL, Oncology, Alkem Laboratories Ltd., Mumbai
2
Dr. Santosh Kumar Goru
(Supervisor) 
Role of histone ubiquitination and ACE2 activation in the progression of renal fibrosis in type I diabetic kidney 9th Jan 2018 Community Pharmacist
New Brunswick, Loblaw companies Limited, Canada
3
Dr. Anuradha Pandey 
(Supervisor)  
Role of epigenetics in modulating inflammatory response mediated by NF-kB through AT1 or AT2 receptor in the development of renal failure under type II diabetic condition 21st March 2018 Senior medical writer, Indegene Ltd, Bengaluru
4
Dr. Vajir Malek 
(Supervisor)
Role of neprilysin in the development of cardiovascular and renal complications associated with type 1 diabetes 5th Feb 2020 Postdoctoral fellow, Beckman Research Institute, City of Hope, California, United States
5
Dr. Nisha Sharm
(Supervisor) 
Involvement of histone H3 methylation, angiotensin converting enzyme 2, and angiotensin II type 2 receptor in the pathogenesis of acute kidney injury under type 1 diabetic and non-diabetic conditions 22nd Oct 2020 Postdoctoral fellow, Arthur Riggs Diabetes Metabolism Research Institute, City of Hope, California, United States
6
Dr. Himanshu Sankrityayan (Supervisor) 
Understanding the role and regulation of endoplasmic stress in the development of endothelial dysfunction and kidney disease under type 1 diabetic condition 27th Sept 2022 Medical Science Liaison (Ophthalmology), North India, Bayer Zydus Pharmaceuticals Pvt. Ltd., Delhi
7
Dr. Ajinath Kale 
(Supervisor)
Klotho regulation as a novel therapeutic strategy against acute kidney injury-diabetes comorbidity   4th Aug 2023 Senior research associate, Pharmacology department, 
Zydus research centre, Ahemadabad, Gujarat
Dr. Vishwadeep Shelke 
(Supervisor) 
Inflammation targeted pharmacotherapy for diabetic acute kidney injury: Exploring novel combinations 6th June 2024 Postdoctoral fellow, Department of Physiology, School of Medicine, Tulane University, New Orleans, LA, United States
Dr. Prabhjeet Singh
(Co-supervisor)
Actively targeted nano-carrier system for the co-delivery of temozolomide and an autophagy modulator for the treatment of glioblastoma multiforme 13th Sept 2024 ---

 

 

Ph.D. Students (Ongoing)

S.No Name Thesis title Year started Status
1 Ms. Ankita Sharma
(Co-supervisor)
Understanding hyperglycemia-induced epigenetic alterations contributing to drug resistance and progression of human pancreatic cancer  Dec 2020 Thesis submitted
2
Ms. Neha Dagar 
(Supervisor)  
Evaluating the role and putative mechanisms of selected nutraceuticals against acute kidney injury under diabetic condition based on network pharmacology approach and experimental validation Sept 2021 Work in progress
3
Ms. Shikha Thakur
(Co-Supervisor)
Design, synthesis, and biological evaluation of Angiotensin II type 1 receptor (AT1R) – neprilysin (NEP) inhibitors (ARNi) against diabetic cardiomyopathy (DCM) Sept 2021  Work in progress
4
Mr. Srinjoy Chakraborty
(Co-Supervisor)
Investigating the epigenetic landscape of histone H4 modifications in endothelial dysfunction during diabetes Sept 2022  Work in progress
5
Mr. Gurmeet Singh
(Co-Supervisor)  
Identification, isolation, characterization of process and degradation impurities of active pharmaceutical ingredients Jan 2023  Work in progress
6
 Mr. Bhupendra Puri
(Supervisor)
Role of long non-coding RNAs in acute kidney injury-to-chronic kidney disease (AKI-to-CKD) transition July 2023  Work in progress
7
Mr. Rohan Bhadange
(Supervisor)
Novel pharmacological interventions against chronic kidney disease using clinically approved inodilators, ET-1A antagonists, and bisphosphonates: drug repurposing approach

Jan 2024 

Work in progress
8
 Mr. Yugant Talati
(Supervisor)
A network pharmacology-based evaluation and experimental validation of phytopharmaceuticals as promising pharmacological interventions for chronic kidney disease Jan 2024  Work in progress
9
 Ms. Mansi Trivedi
(Supervisor)
Study of novel pharmacological combinations against diabetic cardiomyopathy Jan 2024  Work in progress
10
 Mr. Aditya Dipakrao Hajare
(Supervisor)
Pharmacological intervention using α-Klotho with AT1 receptor blocker and sodium-glucose co-transporter 2 (SGLT-2) inhibitor against diabetic kidney disease May 2024 Work in progress

 

 

M. Pharm Students

S.No Name Thesis title Year
1 Mr. Jaspreet Singh To evaluate the hepatoprotective and hepatocurative activity of Punica Granatum peels 2013
2 Mr. Virendra Singh Life saving potential of NMD 04 intravenous fluid against animal models of hemorrhagic shock 2013
3 Mr. Vishakh Prabhkar Biological clock and parkinsonism: Influence of the neurohormone, melatonin on experimental model of parkinson’s disease (Co-supervisor) 2014
4 Mr. Shreyash Bagal To study the expression of angiotensin – II (AT1 & AT2) receptors, oxidative stress and fibrotic markers in the aorta of type II diabetic rats 2015
5 Ms. Vibha Kumari To study the different animal models for AKI 2018
6 Ms. Jyotima Mishra Role PARP inhibitors in fibrosis 2018
7 Ms. Niharika Shiva Simultaneous activation of ACE2 and ER stress inhibition in the development of type 1 diabetic cardiomyopathy 2020
8 Ms. Pooja Dhileepkumar Rao
Role of ER stress inhibition and ACE2 activation in endothelial dysfunction under hyperglycemic condition
2020
9 Mr. Tahib Habshi Evaluating the renoprotective role of hinokitiol against acute kidney injury under diabetic condition 2023
10 Mr. Niraj Patil Exploring the renoprotective potential of bifendate against chronic kidney disease 2024
11 Ms. Shruti Shreya

Evaluating the beneficial effects of guaiacol against chronic kidney disease

2024

 

B. Pharm Students

S.No Name Thesis/Project title Year
1 Mr. Monil Thakkar cGMP for phase I investigational drugs 2011
2 Ms. Masuma Hasan Good manufacturing practices for processing of mesenchymal stromal cells 2011
3 Ms. Anjana Ramnath Current good manufacturing practices for positron emission tomography drugs 2011
4 Mr. Karthik Gangavarapu The Cure: Developing an interactive decision tree builder for breast cancer survival prediction (Co-supervisor) 2014
5 Ms. Garima Partial parallelization of de novo genome assembler (Co-supervisor) 2015
6 Mr. Priyank Raj Role of epigenetics in the development of liver dysfunction under type II diabetic conditions 2016
7 Ms. Ananya Role of hyperglycemia in kidney injury 2017
8 Mr. Lakshya Sharma The preclinical and clinical status of klotho: A review of its therapeutic potential in acute and chronic kidney diseases 2023

 

Research Practice Students

S.No Name Project title Year
1 Ms. Anshima Sharma Clinical outcomes of SGLT2 inhibitors alone and in combination with existing antidiabetic and cardiovascular therapies: an update 2021
2 Mr. Uma Mahesh Epigenetic regulation of ER stress and autophagy in kidney disease 2021
3 Ms. Anjana S. Herbal medicine-the future of diabetic nephropathy treatment 2021
4 Mr. Tahib Habshi Role of endoplasmic reticulum stress and autophagy in acute kidney injury to chronic kidney disease transition 2022
5 Ms. Tathambika Sen Novel promising therapeutic targets for kidney diseases: Emphasis on kidney-specific proteins 2022
6 Ms. Soumya Sikka Role of lncRNAs in the regulation of ER stress in AKI/Kidney diseases 2022
7 Mr. Vinayak Yelgonde Epigenetic regulation of organelle dynamics in kidney diseases 2022
8 Ms. Swati Mishra Immunosuppression in AKI: What to prefer or to avoid 2023
9 Mr. Mayur Chandanani Future therapeutics and biomarkers for diabetic kidney disease: A clinical review 2023
10 Ms. Shruti Shreya Future therapeutics for type 1 diabetes: A clinical review 2023
11 Ms. Shubhangi Saxena Unveiling the therapeutic potential of metabolic reprogramming targeted therapies in kidney diseases 2023
12 Mr. Hrushikesh Kulkarni

The crucial nexus of Polo-like kinase 1 (PLK1) in pathogenesis of kidney diseases

2024