Welcome to the Chemical Glycobiology Lab
In brief: Our research group is working on plant-pathogen interactions in crop plants. Especially we focus on the glycans (carbohydrate) and novel proteins that play important role in plant defense. Identification of these key players will eventually lead to the generation of disease-resistant crops using plant biotechnology tools such as CRISPR/cas9. Our research focus is also on the application part of glycans (carbohydrates) for crop protection and human health.
RP1: Biology: Glycans are carbohydrate-based molecules that play an important role in several biological processes across various domains of life. From a biological perspective, we would like to unravel the roles of novel glycans (in microbes and plants) that are generated by CAZymes (glycosidases and glycosyltransferases) during plant-microbe interactions. Specifically, we would focus on the novel glycan-derived elicitors that are important for immune signaling and disease resistance in crop plants.
RP2: Plant Biotech: The mechanistic insights gained in the RP1 will be used for translational purposes for crop improvement such as generating disease-resistance crops using biotechnology tools such as CRISPR/Cas9.
RP3: Glyco-biotech: Glycan has a tremendous impact on crop protection by acting as elicitors or biostimulants that trigger the plant immune system. We are using cutting-edge glyco analytical technologies to unravel molecules for crop protection. Furthermore, glycans also have a tremendous impact on human health and therapeutics. We aim to synthesize novel glycans in heterologous systems using synthetic biology approaches.
Technology: We will employ state-of-the-art of complex carbohydrate analytics and advanced proteomic approaches to address our research questions.
An Institute of Eminence
