Dr. Aditya Sharma

Assistant Professor, Department of Biotechnology

Bioinformatics and Computational Biology, human genetics, Next Generation Sequencing data analysis (WES), Computer Aided Drug Design, computational chemistry/cheminformatics, computational genomics, genetic disorders (Mendelian and complex)
Room No. 317, BITS Pilani, Dubai Campus Dubai International Academic City P.O. Box No. – 345055, Dubai, UAE


  1. Saini M, Upadhyay N, Dhiman K, Manjhi SK, Kattuparambil AA, Ghoshal A, Arya R, Dey SK, Sharma A, Aduri R, Thelma BK, Ashish F, Kundu S. ARL15, a GTPase implicated in rheumatoid arthritis, potentially repositions its truncated N-terminus as a function of guanine nucleotide binding. International Journal of Biological Macromolecules. 2023 Nov 6:127898. doi: 10.1016/j.ijbiomac.2023.127898. Epub ahead of print. PMID: 37939768. ISSN: 0141-8130, 1879-0003
  2. Saini M, Anand V, Sharma A, Pandey A, Thelma BK, Kundu S. ARL15 and its multiple disease associations: Emerging functions and potential therapeutic applications; Current Protein & Peptide Science,  2023 Sep 15. doi: 10.2174/1389203724666230915123217. Epub ahead of print. PMID: 37718516. ISSN: 13892037, 18755550
  3. Sharma A, Saini M, Kundu S, Thelma BK. Computational insight into the three-dimensional structure of ADP Ribosylation factor like protein 15, a novel susceptibility gene for rheumatoid arthritis; Journal of Biomolecular Structure and Dynamics, 2020 Dec Dec 23;1-16. doi: 10.1080/07391102.2020.1860826.: Print ISSN: 0739-1102 Online ISSN: 1538-0254
  4. Sharma A, Thelma BK; Pharmacophore modeling and virtual screening in search of novel Bruton’s Tyrosine Kinase inhibitors; Journal of Molecular Modelling, 2019 Jun 6;25(7):179. doi:10.1007/s00894-019-4047-y : Electronic ISSN 0948-5023 Print ISSN 1610-2940
  5. John J, Kukshal P, Sharma A, Bhatia T, Nimgaonkar VL, Deshpande SN, Thelma BK; Rare variants in Protein tyrosine phosphatase, receptor type A (PTPRA) in schizophrenia: Evidence from a family based study; Schizophrenia Research, 2019 Apr;206:75-81; doi: 10.1016/j.schres.2018.12.012 : (2020) ISSN: 0920-9964
  6.   John J, Sharma A, Kukshal P, Bhatia T, Nimgaonkar VL, Deshpande SN, Thelma BK; Rare Variants in Tissue Inhibitor of Metalloproteinase 2 as a Risk Factor for Schizophrenia: Evidence From Familial and Cohort Analysis; Schizophrenia Bulletin, 2019 Jan 1;45(1):256-263; sbx196, : ISSN: 0586-7614 (print); 1745-1701 (web)
  7. Jatana N, Apoorva N, Malik S, Sharma A, Latha N; Inhibitors of catechol-O-methyltransferase in the treatment of neurological disorders; Central nervous system agents in medicinal chemistry, 2013;13(3):166-94; DOI: 10.2174/1871524913666140109113341; ISSN - 1871-5249
  8.  Jatana N, Sharma A, Latha N; Pharmacophore modeling and virtual screening studies to design potential COMT inhibitors as new leads; Journal of Molecular Graphics and Modelling, 2013; 39:145-64; DOI10.1016/j.jmgm.2012.10.010; ISSN - 1093-3263
  9. Sharma A, Pan AIdentification of potential drug targets in Yersinia pestis using metabolic pathway analysis: MurE ligase as a case study; European Journal of Medicinal Chemistry, 2012; Nov,57, 185-195; DOI: 10.1016/j.ejmech.2012.09.018; ISSN: 0009-4374 (print), 0223-5234 (web)



  • Oral presentation on “Computer Aided Drug Discovery Efforts for Rheumatoid Arthritis” at the 8th National Science Day Symposium, at University of Delhi South Campus, New Delhi; 27th – 28th February, 2019
  • Poster on “Development of Lead Molecules for Complex Genetic Disorders: Rheumatoid Arthritis – A Case Study” by Sharma A. & Thelma B.K, presented at the 42nd Annual Meeting of the Indian Society of Human Genetics (ISHG) & International Symposium on Trends in Human Genetic Research & Management, at Indian Institute of Science (IISc.), Bangalore; 2nd to 4th March, 2017. (Best poster award)
  • Abstract on “Integrating CADD Methodologies for the Design of Novel COMT Inhibitors” by Nidhi Jatana, Aditya Sharma and N. Latha for poster presentation at “Albany 2011: the 17th  conversation”, ”, published in “Book of Abstracts: Albany 2011” - Albany 2011, Conversation 17, June 14-18 2011©Adenine Press (2010)