Ghosh S, Isma J, Mazzeo L, Toniolo A, Ostano P, Das M, Simon C, Dotto G. P, Nuclear lamin A/C phosphorylation by loss of Androgen Receptor is a global determinant of cancer-associated fibroblast activation (In revision Nature Communications).
Mazzeo L, Ghosh S, Di Cicco E, Isma J , Tavernari D , Samarkina A, Ostano P, Youssef MK, Simon C & Dotto GP, ANKRD1 is a mesenchymal-specific driver of cancer-associated fibroblast activation, bridging loss of the androgen receptor to AP-1 activation. Nature Communications, 2024, 15:1038.
Samarkina A, Youssef MK, Ostano P, Ghosh S, Ma M, Tassone B, Proust T, Chiorino G, Levesque M. P, Goruppi S, Dotto GP, Androgen Receptor is a Determinant of Melanoma targeted drug resistance. Nature Communications, 2023; 14: 6498.
Ma M*, Ghosh S*, Tavernari D, Katarkar A, Clocchiatti A, Mazzeo L, Samarkina A, Epiney J, YuYi-Ru, Ho PC, Levesque M, Özdemir BC, Ciriello G, Dummer R, & Dotto GP. Sustained AndrogenReceptor signaling is a determinant of melanoma cell growth potential and tumorigenesis. Journal of Experimental Medicine, 2021, 218: e20201137. (*Contributed equally)
Bottoni G, Katarkar A, Tassone B, Ghosh S, Clocchiatti A, Goruppi S, Bordignon P, Jafari P, Tordini F, Lunardi T, Hoetzenecker W, Neel V, Lingner J & Dotto GP. CSL controls telomere maintenance and genome stability in human dermal fibroblasts. Nature Communications, 2019, 10, 3884.
Datta C, Jha RK, Ahmed W, Ganguly S, Ghosh S, Nagaraja V. Physical and functional interactionbetween nucleoid-associated proteins HU and Lsr2 of Mycobacterium tuberculosis: altered DNAbinding and gene regulation. Molecular Microbiology, 2019, 111: 981–994.
Clocchiatti A*, Ghosh S*, Procopio MG, Mazzeo L, Bordignon P, Ostano P, Goruppi S, Bottoni G,Katarkar A, Levesque M, Kölblinger P, Dummer R, Neel V, Berna C. Özdemir BC & Dotto GP.Androgen receptor functions as a transcriptional repressor of Cancer Associated Fibroblast (CAF)activation. Journal of Clinical Investigations, 2018, 128: 5531-5548. (*Contributed equally)
Kim DE*, Procopio MG*, Ghosh S*, Jo SH, Goruppi S, Magliozzi F, Bordignon P, NeelV, Angelino P, & Dotto GP. Convergent roles of ATF3 and CSL in chromatin control of cancer-associated fibroblast activation. Journal of Experimental Medicine, 2017, 214: 2349-2368.
Anand C, Garg R, Ghosh S, & Nagaraja V. A Sir2 family protein Rv1151c deacetylates HU to alter its DNA binding mode in Mycobacterium tuberculosis. Biochem Biophys Res Commun, 2017, 493:1204-1209.
Ghosh S, Padmanabhan B, Anand C & Nagaraja V. Lysine acetylation of the Mycobacterium tuberculosis HU protein modulates its DNA binding and genome organization. Molecular Microbiology, 2016, 100: 577-588.
Ghosh S, Padmanabhan B, Godbole AA, Tare P, Ahmed W, Vasu K, China A, Kumar R, Mitra A & Nagaraja V. Transcriptional regulation of topology modulators and transcription regulators of Mycobacterium tuberculosis. Biochem Biophys Res Commun., 2016, 475:257-263.
Bhowmick T*, Ghosh S*, Dixit K, Ganesan V, Ramagopal UA, Dey D, Sarma SP, Ramakumar S& Nagaraja V. Targeting Mycobacterium tuberculosis nucleoid-associated protein HU withstructure-based inhibitors. Nature Communications, 2014, 5, 4124. (*Contributed equally)
Ghosh S, Mallick B & Nagaraja V. Direct control of mycobacterial topoisomerase I activity by anucleoid-associated protein. Nucleic Acids Research, 2014, 42:11156-11165.
Gupta M, Sajid A, Sharma K, Ghosh S, Arora G, Singh R, Nagaraja V, Tandon V & Singh Y. HupB, a nucleoid-associated protein of Mycobacterium tuberculosis, is modified by serine/threonine protein kinases in vivo. Journal of Bacteriology, 2014, 196: 2646-2657.
Ghosh S, Indi SS & Nagaraja V. Regulation of lipid biosynthesis, sliding motility and biofilmformation by a membrane-anchored nucleoid-associated protein of Mycobacterium tuberculosis. Journal of Bacteriology. 2013, 195: 1769-1778.
Sengupta S, Ghosh S & Nagaraja V. Moonlighting function of glutamate racemase from Mycobacterium tuberculosis: racemization and DNA gyrase inhibition are two independent activities of the enzyme. Microbiology. 2008, 154: 2796-2803.
Suryanarayanarao R, Bhowmick T, Ghosh S, Udupi R A & Nagaraja V. Crystal structure and structure-based drug design of HU (histone-like protein) from tuberculosis, Acta Cryst. 2008, A64, C342.
Saravanan M, Vasu K, Ghosh S & Nagaraja V. Dual role for Zn2+in maintaining structural integrity and inducing DNA sequence specificity in a promiscuous endonuclease. Journal of Biological Chemistry, 2007, 282: 32320-32326.