Dr. Atish T. Paul

Associate Professor, Department of Pharmacy,
BITS Pilani, Pilani Campus

Natural Product Chemistry
Department of Pharmacy, Birla Institute of Technology & Science, Pilani- 333031, Rajasthan. India.
Atish T. Paul



Research Articles


  • U Jagtap, A T Paul. UCP1 activation: hottest target in the thermogenesis pathway to treat obesity using molecules of synthetic and natural origin. Drug Discovery Today, 103717 [IF=7.4]
  • P Auti, S Jagetiya, A T Paul. Chromone-3-acrylic acid ester Analogues: Design, Synthesis and Biological Evaluation as Potential Pancreatic Lipase Inhibitors. Journal of Molecular Structure [IF=3.8]
  • P Auti, S Jagetiya, A T Paul. Chromone Containing Hybrid Analogues: Synthesis and Applications in Medicinal ChemistryChemistry & Biodiversity, e202300587 [IF=2.9]
  • KS Prayag, A T Paul, S Kumar, A B Jindal. Preclinical evaluation of quinapyramine sulphate-loaded lipidic nanocarriers for trypanocidal effect against Trypanosoma evansiJournal of Drug Delivery Science and Technology, 2023, 81, 104215 [IF=5.062]
  • M Sandhu, A T Paul, J Procków, J M P de la LastraP N Jha. PCB-77 biodegradation potential of biosurfactant producing bacterial isolates recovered from contaminated soil. Frontiers in Microbiology, 2022 13:952374 [IF- 6.064]
  • P Auti, A Nandi, V Kumari, A T Paul. Design, synthesis, biological evaluation and molecular modelling studies of oxoacetamide warhead containing indole-quinazolinone based novel hybrid analogues as potential pancreatic lipase inhibitors. New Journal of Chemistry, 2022, 46, 11648-11661 [IF- 3.925

  • G George, P Auti, P Sengupta, AT Paul. Design and Synthesis of Echitamine-Inspired Hybrid Analogues Containing Thiazolidinediones as Potential Pancreatic Lipase Inhibitors. Letters in Drug Design 2022,19 (11),956 - 968 [IF- 1.099]

  • M Sandhu, AT Paul, P N Jha. Metagenomic analysis for taxonomic and functional potential of Polyaromatic hydrocarbons (PAHs) and Polychlorinated biphenyl (PCB) degrading bacterial communities in steel industrial soil. PLOS one 2022, 17(4) e0266808  [IF- 3.24]

  • P Sengupta, N Tiwari, T Bhat, A T Paul. Mechanistically acting anti-obesity compositions/formulations of Natural origin: A Patent Review (2010-2021), Expert Opinion on Therapeutic Patents 2022 32(1),29-46  [IF-6.674]
  • <span "="">SNC<span "=""> Sridhar,  <span "="">P Sengupta, <span "="">S Palawat, PS <span "="">Dileep , <span "="">G George , <span "="">A T Paul. Synthesis, molecular modelling, in vitro and in vivo evaluation of conophylline inspired novel benzyloxy substituted Indole glyoxylamides as potent pancreatic lipase inhibitors, Journal of Structure and Biomolecular Dynamics 2021,25,1-13  [IF-3.549]
  • G George, P Auti , AT Paul. Design, synthesis and biological evaluation of N-substituted indole-thiazolidinedione hybrid analogues as potential pancreatic lipase inhibitors, Chemical Biology & Drug  Design 2021,98(1),49-59 [IF-2.548]

  • P Bhutani, G Joshi, N Raja, N Bachhav, PK Rajanna, H Bhutani, AT Paul*, R Kumar*. U.S. FDA Approved Drugs from 2015−June 2020: A Perspective, Journal of Medicinal Chemistry 2021, 64(5),2339-2381 [IF-6.205]

  • KS Prayag, AT Paul, SK Ghorui, AB Jindal. Preparation and Evaluation of Quinapyramine Sulphate-Docusate Sodium Ionic Complex Loaded Lipidic Nanoparticles and Its Scale Up Using Geometric Similarity Principle.  Journal of Pharmaceutical Sciences, 2021,110(5):2241-2249  [IF-2.997]

  • G George, P Sengupta, AT Paul. Design, synthesis, in silico molecular modelling studies and biological evaluation of novel indole-thiazolidinedione hybrid analogues as potential pancreatic lipase inhibitors. New Journal of Chemistry 2021, 45, 1381 - 1394  [IF-3.288]

  • P Auti, G George, AT Paul. Recent advances in the pharmacological diversification of quinazoline/quinazolinone hybrids. RSC Advances 2020,10, 41353-41392 [IF-3.119]
  • G George, SNC Sridhar, AT Paul. Investigation of anti-obesity potential of green tea polyphenols and orlistat  combination using pancreatic lipase assay based synergy directed fractionation strategy. South African Journal of   Botany. 2020,135,50-57 [IF-1.792]
  • N Yadav, P Auti, G George and AT Paul. Design, synthesis and biological evaluation of O-alkyl umbelliferone derivatives as pancreatic lipase inhibitors. Journal Indian Chemistry Society, 2020, 97(8),1-6 [IF-0.150]
  • P Bhutani, PK Rajanna, AT Paul. Impact of quercetin on pharmacokinetics of quetiapine: Insights from in-vivo studies in wistar rats. Xenobiotica,2020, 50(12) 1483-1489 [IF-1.770]
  • SNC Sridhar, S Palawat, AT Paul. Design, synthesis, biological evaluation and molecular modelling studies of conophylline Inspired novel indolyl oxoacetamides as potent pancreatic lipase inhibitors. New Journal of Chemistry, 2020,44,12355-12369 [IF-3.288]
  • G George, P Sengupta, AT Paul. Optimization of an extraction conditions for Rumex nepalensis anthraquinones and its correlation with pancreatic lipase inhibitory activity. Journal of Food Composition and Analysis 2020,92,202,103575 [IF-3.721]
  • M Sandhu, P Jha, AT Paul, RP Singh and P N Jha. Evaluation of biphenyl- and polychlorinated-biphenyl (PCB) degrading Rhodococcus sp. MAPN-1 on growth of Morus alba by pot studyInternational Journal of Phytoremediation 2020,23(14),1487-1496 [IF-2.237]
  • P Bhutani, R U, HN Shivakumar, KR Prabhakar, AT Paul. Rapid and cost‐effective LC‐MS/MS method for determination of hydroxycitric acid in plasma: Application in the determination of pharmacokinetics in commercial Garcinia preparations. Biomedical Chromatography, 2020, 34(10), e4902 [IF-1.748]
  • SNC Sridhar, S Palawat, AT Paul. Design, synthesis, evaluation, and molecular modeling studies of indolyl oxoacetamides as potential pancreatic lipase inhibitors. Archiv der Pharmazie 2020,353 (8),2000048 [IF- 2.145]
  • K Prayag, DH Surve, AT Paul, S Kumar, AB Jindal. Nanotechnological interventions for treatment of trypanosomiasisin humans and animals. Drug Delivery and Translational Research, 1-17 [IF- 3.111]
  • G George, Dileep P.S, AT Paul. Development and validation of a new HPTLC-HRMS method for the quantification of a potent pancreatic lipase inhibitory lead Echitamine from Alstonia scholarisNatural Product Research, 1-5 [IF-1.999]
  •  D Chauhan, G George, SNC Sridhar, R Bhatia, AT Paul, V Monga. Design, synthesis, biological evaluation, and molecular modeling studies of rhodanine derivatives as pancreatic lipase inhibitors. Archiv der Pharmazie 352 (10), 1900029 [IF- 2.145]
  • SNC Sridhar, S Palawat, AT Paul. Design, synthesis, biological evaluation and molecular modelling studies of indole glyoxylamides as a new class of potential pancreatic lipase inhibitors. Bioorganic Chemistry 85, 373-381 [IF-4.831]
  • G Joshi, AA Wani, S Sharma, P Bhutani, PV Bharatam, AT Paul, R Kumar. Unanticipated Cleavage of 2-Nitrophenyl-Substituted N-Formyl Pyrazolines under Bechamp Conditions: Unveiling the Synthesis of 2-Aryl Quinolines and their  and Their Mechanistic Exploration via DFT Studies. ACS Omega 3 (12), 18783-18790 [IF-2.87]
  • SNC Sridhar, P Sengupta, AT Paul. Development and validation of a new HPTLC method for quantification of conophylline in Tabernaemontana divaricata samples obtained from different seasons and extraction  techniques: Insights into variation of pancreatic lipase inhibitory activity. Industrial Crops and Products 111, 462-470 [IF-4.244]
  • P Sengupta, S Raman, R Chowdhury, K Lohitesh, H Saini, S Mukherjee, AT Paul. Evaluation of apoptosis and autophagy inducing potential of Berberis aristataAzadirachta indica, and their synergistic combinations in parental and resistant human  osteosarcoma cells. Frontiers in Oncology 7, 296 [IF-4.848]
  • M Katoch, AT Paul, G Singh, SNC Sridhar. Fungal endophytes associated with Viola odorata Linn. as bioresource for pancreatic lipase inhibitors. BMC Complementary and Alternative Medicine 17 (1), 385 [IF-2.610]
  • SNC Sridhar, D Bhurta, D Kantiwal, G George, V Monga, AT Paul. Design, synthesis, biological evaluation and molecular modelling studies of novel diaryl substituted pyrazolyl thiazolidinediones as potent pancreatic lipase inhibitors. Bioorganic & Medicinal Chemistry Letters 27 (16), 3749-3754 [IF-2.572]
  • SNC Sridhar, S Mutya, AT Paul. Bis-indole alkaloids from Tabernaemontana divaricata as potent pancreatic lipase inhibitors: molecular modelling studies and experimental validation. Medicinal Chemistry Research 26 (6), 1268-1278 [IF-1.783]
  • SNC Sridhar, G Ginson, POV Reddy, MP Tantak, D Kumar, AT Paul. Synthesis, evaluation and molecular modelling studies of 2-(carbazol-3-yl)-2-oxoacetamide analogues as a new class of potential pancreatic lipase inhibitors.Bioorganic & Medicinal Chemistry 25 (2), 609-620 [IF-3.073]
  • SD Katekhaye, AT Paul, KS Laddha. Lupane Analogue from Bark of Pithecellobium dulce and in vitro α-glucosidase and α-amylase enzyme inhibition assay of extract for potential antidiabetic activity. Chemistry of Natural Compounds 52 (2), 359-362 [IF-0.567]
  • S. Kumari, AT Paul, SNC. Sridhar. Diabetic Complications: A Natural Product Perspective. Pharmaceutical Crops 5, 39-60
  • M Singh, N Kaur, AT Paul. Physicochemical standardization, HPTLC profiling, and biological evaluation of Asvagandhadyarista: A comparative study of three famous commercial brands. Ancient Science of Life 33 (3), 165
  • KK Bhutani, AT Paul, W Fayad, S Linder. Apoptosis inducing activity of steroidal constituents from Solanumxanthocarpum and Asparagus racemosusPhytomedicine 17 (10), 789-793 [IF-4.268]
  • AT Paul, S Vir, KK Bhutani. Liquid chromatography–mass spectrometry-based quantification of steroidal glycoalkaloids from Solanum xanthocarpum and effect of different extraction methods on their content. Journal of Chromatography A 1208 (1-2), 141-146 [IF-4.049]
  • RU Kadam, D Garg, AT Paul, KK Bhutani, N Roy. Evaluation of pro-inflammatory cytokine pathway inhibitors for p38 MAPK inhibitory potential. Journal of Medicinal Chemistry 50 (25), 6337-6342 [IF-6.205]
  • AS Kanwar, AT Paul, KK Bhutani. Pro-inflammatory cytokines and nitric oxide inhibitory activity of two Indian   medicinal plants.  Inflammation Research [Conference Proceedings] 56, S399-S400
  • AT Paul, VM Gohil, KK Bhutani. Modulating TNF-α signaling with natural products. Drug Discovery Today 11 (15-16), 725-732 [IF-7.321]


  •  Antimicrobial Resistance: Underlying Mechanism and Therapeutic Approaches [Editors: Dr. Vinay Kumar, Dr. Varsha Shriram, Dr. Atish Paul & Dr. Mansee Thakur]



Book Chapters

  • K Sriravali, AB Jindal, B P Singh, AT Paul. Plant associated endophytic fungi and its secondary metabolites against drug resistant pathogenic microbes In: Antimicrobial Resistance: Underlying Mechanisms & Therapeutic Approaches [SPRINGER NATURE, Switzerland]
  • G George, N Yadav, A Jeswani, P Auti. Pharmaceutical Application of Bio-actives from Alstonia Genus: Current Findings and Future Directions In: Bioactive Natural Products for Pharmaceutical Applications, [SPRINGER NATURE, Switzerland]
  • SNC Sridhar, G George, A Verma, AT Paul. Natural Products-Based Pancreatic Lipase Inhibitors for Obesity Treatment In: Natural Bio-active Compounds, 149-191, [SPRINGER NATURE, Switzerland]
  • DH Surve, AT Paul, AB Jindal. Nanotechnology Based Delivery of Nutraceuticals In: Environmental Nanotechnology,63-107 [SPRINGER NATURE, Switzerland]
  • AT Paul, A Jindal. Nano-natural Products as Anticancer Agents In: Anticancer Plants: Clinical Trials and Nanotechnology, 27-50 [SPRINGER NATURE, Switzerland]