Dr. Mainak Dutta

Assistant Professor, Department of Biotechnology 

Applied Biochemistry, Systems Biology, Proteomics, Metabolomics, Cancer therapeutics
BITS Pilani, Dubai Campus Dubai International Academic City P. O. Box No. - 345055  Dubai, UAE Chamber no:314

Mainak Dutta was awarded PhD from the Indian Institute of Technology Kharagpur, India in 2016. He is the recipient of Fulbright USA Doctoral Research Fellowship, United States-India Educational Foundation (USIEF), 2014. He was a visiting doctoral research scholar at Pennsylvania State University, USA from 2014-2015. He was also awarded the Sigma Xi Grants-in-Aid for graduate research, Sigma Scientific Research Society, USA, 2015. After completing his PhD he joined the Institute of Genomics and Integrative Biology, India as a postdoctoral fellow. In 2017, Dr. Dutta joined the Department of Biotechnology, Birla Institute of Technology Pilani-Dubai Campus as Assistant Professor.

Mainak Dutta has expertise in systems biology and the use of ‘omics’ approaches, such as proteomics, transcriptomics, and metabolomics, to identify biomarkers and understand disease pathogenesis. Currently, his research group uses these approaches to identify novel drug targets against cancer pathways, especially, but not limited to, cancer metabolic pathways.

Cancer is a polygenic disease associated with altered metabolic pathways as a result of continuous demand for energy and nutrients. Though most of the cancer promoting genes are widely studied for their role in cancer signaling pathways, their propensity to regulate metabolic pathways is not well understood. Mainak Dutta aims to understand the role of these genes in bidirectional relationship between cancer signaling pathways and metabolism from a Systems view. His research group uses a combination of high throughput omics, basic research, bioinformatics and mammalian tissue culture models to translate the findings into effective therapeutics

The current research areas of the lab are:

  • Role of cell cycle regulatory kinases in cancer cell metabolism
  • Cell cycle regulatory kinases and chaperones as therapeutic targets
  • Synergistic therapy and drug repurposing to decrease dose-related toxicity in cancer chemotherapy
  • Metabolomics approaches using LC-MS/MS and GC-MS to identify metabolites and lipids