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  • Page last updated on Wednesday, February 20, 2013

Dr. Anil Kumar

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Innovate. Achieve. Lead

Patent

K  Parang, G Sun, Anil Kumar, NH Nam, Y Wang, G Ye, Bisubstrate inhibitors of Src  tyrosine kinases and therapeutic agents, Patent No WO 2005117932, 2005.

Book Chapter

Anil Kumar, SR Meneni, Recent synthetic  methodologies for furan derivatives in “Modern Approaches to the Synthesis of O-  and N- Heterocycles” Chapter 2, Vol. 1, Ed Teodoro S. Kaufman and Enrique L. Larghi; Research Signpost, 2007, Vol. 1, Chapter 2

Research Papers in Referred Journals

2013 

70. K. Pericherla, P. Khedar, B. Khungar, Anil Kumar,  One-pot sequential C-N coupling and cross dehydrogenative couplings: Synthesis of novel azole fused imidazo[1,2-a]pyridines, Chem. Commun. 2013, (in press).

69.  B. Mishra, KP Chandra Shekar, Anil Kumar, S Phukan, S Mitra, D Kumar, Facile synthesis, characterization and fluorescence studies of novel porphyrin appended thiazoles, J. Heterocyclic Chem. 2013, (in press).

68. D Kumar, BA Mishra, KP Chandra Shekar, Anil Kumar, K Akamatsu, E Kusaka, T Ito, Remarkable photocytotoxicity of a novel triazole–linked cationic porphyrin–β–carboline conjugate, Chem. Commun. 2013, 49, 683-685.

67. S Phukan, B Mishra, KP Chandra Shekar, Anil Kumar, D Kumar, S Mitra, Fluorescence spectroscopic studies on substituted porphyrins in homogeneous solvents and cationic micellar mediumJ. Luminescence 2013, 134, 232-239.

 2012 

66. Anil Kumar, MS Rao, An expeditious and greener one-pot synthesis of 4H-chromenes catalyzed by Ba(OTf)2 in PEG-water, Green Chem. Lett. Rev. 2012, 5, 283-290.

65. K Pericherla, P Khedar, B Khungar, Anil Kumar, Click chemistry inspired structural modification of azole antifungal agents to synthesize novel “drug like” molecules, Tetrahedron Lett. 2012, 53, 6761-6764.

64. P Khedar, K Pericherla, Anil Kumar, Exploration of CuAAC reaction for the synthesis of novel 3-(triazol-1-yl)methyl-imidazo[1,2-a]pyridines, Synlett 2012, 2609-2614.

63. MS Rao, BS Chhikara, R Tiwari, AN Shirazi, K Parang, Anil Kumar, A greener synthesis of 2-aminochromenes in ionic liquid and evaluation of their antiproliferative activities, Chem. Bio. Interface 2012, 2, 362-372.

62. Anil Kumar, MK Muthyala, S Choudhary, RK Tiwari, K Parang,  Ionic liquid as soluble support for synthesis of 1,2,3-thiadiazoles and 1,2,3-selenadiazoles, J. Org. Chem. 201277, 9391−9396.

61. MK Muthyala, S Choudhary, Anil Kumar, Synthesis of ionic liquid-supported sulfonyl azide and its application in diazotransfer reaction, J. Org. Chem. 201277, 8787-8791.

60. M Rathore, A Dalvi, Anil Kumar, Ionic liquid [Bmim][BF4] - glass composites for solid state battery applications, Int. J. Phy. Math. Sci. 2012, 2(S1), 1-5.

59. D Kumar, KP Chandrashekar, B Mishra, Anil Kumar, K Akamatsu, E Kusaka, T Ito, A facile synthesis and cytotoxicity of a novel porphyrin-cryptolepine conjugate, Chem. Bio. Interface 20122, 112-114.

58. MK Muthyala, Anil Kumar, A novel and efficient one pot synthesis of 2,4-disubstituted thiazoles and oxazoles using PTT in ionic liquid, J. Heterocyclic Chem. 2012, 49, 959-964.

57. B Khungar, MS Rao, K Pericherla, P Nehra, N Jain, J Panwar, Anil Kumar, Synthesis, characterization and microbiocidal studies of novel ionic liquid tagged Schiff bases, C. R. Chimie 2012, 15, 669-674.

56. Anil Kumar, MK Muthyala, BS Chhikara, K Parang, Ionic liquid supported TBD: An efficient and recyclable organocatalyst for Michael addition to α,β-unsaturated ketones, Can. J. Chem. 2012, 90, 290-297.

55. K Pericherla, B Khungar, Anil Kumar, One-pot, three-component synthesis of 1-amidomethyl-imidazo[1,2-a]pyridines catalyzed by ytterbium triflates, Tetrahedron Lett. 2012, 53, 1253–1257.

54. MS Rao, BS Chhikara, R Tiwari, AN Shirazi, K Parang, Anil Kumar, Microwave-Assisted and scandium triflate catalyzed synthesis of tetrahydrobenzo[a]xanthen-11-ones, Monatsh Chem. 2012, 143, 263–268.

53. MK Muthayala, Anil Kumar, Ionic liquid supported aldehyde: A highly efficient scavenger for primary amines, ACS Comb. Sci. 2012, 14, 5-9.

52. MK Muthyala, BS Chhikara, K Parang, Anil Kumar, Ionic liquid-supported synthesis of sulfonamides and carboxamides, ACS Comb. Sci. 2012, 14, 60−65.

51. VK Rao, BS Chhikara, R Tiwari, AN Shirazi, K Parang, Anil Kumar, One-pot regioselective synthesis of tetrahydroindazolones and evaluation of their anticancer and Src kinase inhibition activities, Bioorg. Med. Chem. Lett. 2012, 22, 410–414.

50. K Soni, Anil Kumar, AK Sah, Saccharide derived dinuclear Cu(II) complex: An efficient catalyst for oxidation of catechol and benzylic alcohols, Catal. Commun. 2012, 17, 95–98.

2011

49. VK Rao, MS Rao, Anil Kumar, Ytterbium(III) triflate: An efficient and simple catalyst for isomerization of 2´-hydroxychalcone and 2´-aminochalcones in ionic liquid, J. Heterocyclic Chem. 2011, 48, 1356-1360.

48. VK Rao, MS Rao, N Jain, J Panwar, Anil Kumar, Silver triflate catalyzed synthesis of 3-aminoalkylated indoles and evaluation of their antibacterial activities, Org. Med. Chem. Lett. 2011, 1, 10.

47. Anil Kumar, MK Muthyala, 1-Butyl-3-methylimidazolium p-toluenesulfinate: A novel reagent for synthesis of β-ketosulfones in ionic liquid, Tetrahedron Lett. 2011, 52, 5368–5370.

46. VK Rao, BS Chhikara, AN Shirazi, R Tiwari, K Parang, Anil Kumar, 3-Substitued indoles: One-pot synthesis and evaluation of anticancer and Src kinase inhibitory activities, Bioorg. Med. Chem. Lett.2011, 21, 3511-3514.

45. Anil Kumar, VK Rao, Microwave-assisted and Yb(OTf)3 promoted one-pot multicomponent synthesis of substituted quinolines in ionic liquid, Synlett 2011, 2157-2162.

44. MK Muthyala, VK Rao, Anil Kumar, Cu(OTf)catalyzed synthesis of bis(5-methyl-2-furyl)methanes by condensation of 2-methylfuran with carbonyl compounds under solvent free conditions, Chin. J. Chem.2011, 29, 1483–1488.

43. Anil Kumar, MS Rao, V Mehta, A simple and efficient bromoazidation of alkenes using PTT and TMSN3in ionic liquid, Indian J. Chem. 2011, 50B, 1123-1127.

42. VK Rao, MM Kumar, Anil Kumar, An efficient and simple synthesis of tetraketones catalysed by Yb(OTf)3-SiO2 under solvent free conditions, Indian J. Chem. 2011, 50B, 1128-1135.

41. BS Chhikara, NS Jean, D Mandal, Anil Kumar, K Parang, Fatty-acyl amide derivatives of doxorubicin: Synthesis and in vitro anticancer activities, Eur. J. Med. Chem. 2011, 46, 2037-2042.

40. Anil Kumar, I Ahmad, BS Chhikara, R Tiwari, D Mandal, K Parang, Synthesis of 3-phenylpyrazolopyrimidine-1,2,3-triazole conjugates and evaluation of their Src kinase inhibitory and anticancer activities, Bioorg. Med. Chem. Lett. 2011, 21, 1342-1346.

39. D Kumar, VB Reddy, Anil Kumar, D Mandal, R Tiwari, K Parang, Click chemistry inspired one-pot synthesis of 1,4-disubstituted 1,2,3-triazoles and their Src kinase inhibitory activity, Bioorg. Med. Chem. Lett. 2011, 21, 449-452.

2010

38. KP Chandra Shekar, B Mishra, Anil Kumar, S Phukan, S Phukan Mitra, D Kumar, Synthesis and fluorescence studies of porphyrin appended 1,3,4-oxadiazoles, J. Porphyrin Phthalocyanines 2010, 14, 1034-1039.

37. HK Agarwal, Anil Kumar, GF Doncel, K Parang Synthesis, antiviral and contraceptive activities of nucleoside–sodium cellulose sulfate acetate and succinate conjugates, Bioorg. Med. Chem. Lett. 2010, 20, 6993–6997.

36. Anil Kumar, MS Rao, VK Rao, Sodium dodecyl sulfate-assisted synthesis of 1-(benzothiazolylamino)methyl-2-naphthols in water, Aust. J. Chem. 2010, 63, 1538–1540.

35. Anil Kumar, MS Rao, VK Rao, Cerium triflate: An efficient and recyclable catalyst for chemoselective thioacetalization of carbonyl compounds under solvent-free conditions, Aust. J. Chem. 2010, 63, 135-140.

34. D. Kumar, S Sundaree, G Patel, Anil Kumar, A novel and short synthesis of naturally occurring 5-(3'-indolyl)oxazoles, J. Heterocyclic Chem. 2010, 47, 1425-1428.

2009

33. D Kumar, G Patel, Anil Kumar and RK Roy, Ionic liquid catalyzed expeditious synthesis of 2-aryl-2,3-dihydroquinolin-4(1H)-ones and 2-aryl-2,3-dihydro-4H-chromen-4-ones under microwave irradiation,J. Heterocycl. Chem. 2009, 46, 791.

32. MS Rao, I Ahmad, B Khungar, Anil Kumar, A simple and facile synthesis of b-amidoalkyl naphthols catalyzed by ytterbium triflate in ionic liquid, Can. J. Chem. 2009, 87, 714.

31. Anil Kumar, MS Rao, I Ahmad, B Khungar, An efficient and simple one-pot synthesis of b-acetamido ketones catalyzed by ytterbium triflate in ionic liquid, Aus. J. Chem. 2009, 62, 322.

30. Anil Kumar, I Ahmad, MS Rao, Yb(OTf)3 Immobilized in [bmim][BF4]: A simple and efficient catalyst for thia-Michael addition to a,b-unsaturated ketones, J. Sulfur Chem. 2009, 30, 570.

29. Anil Kumar, I Ahmad, MS Rao, G Patel, D Kumar, An efficient PTT-mediated synthesis of a-azidoketones in ionic liquids, Indian J. Chem. 2009, 48B, 611.

2008

28. Anil Kumar, I Ahmed, MS Rao, Ytterbium triflate catalyzed synthesis of calix[4]pyrroles in ionic liquids,Can. J. Chem. 2008, 86, 899-902.

27. S Penugonda, Anil Kumar, HK Agarwal, K Parang, R Mehvar, Synthesis and in vitro characterization of novel dextran-methylprednisolone conjugates with peptide linkers: Effects of linker length on hydrolytic and enzymatic release of methylprednisolone and its peptidyl intermediates, J. Pharm. Sci. 2008, 97, 2649-2664.

2007

26. KC Chimalakonda, HK Agarwal, Anil Kumar, K Parang, R Mehvar, Synthesis, analysis, in vitro characterization, and in vivo disposition of a lamivudine-dextran conjugate for selective antiviral delivery to the liver, Bioconjugate Chem. 2007, 18, 2097-2108.

25. Anil Kumar, Y Wang, X Lin, G Sun, K Parang, Synthesis and evaluation of 3-phenylpyrazolo[3,4-d]pyrimidine-peptide conjugates as Src kinase inhibitors, ChemMedChem 2007, 2, 1346-1360.

24. G Ye, NH Nam, Anil Kumar, A Saleh, DB Shenoy, MM Amiji, X Lin, G Sun, K Parang, Synthesis and evaluation of tripodal peptide analogues for cellular delivery of phosphopeptides, J. Med. Chem. 2007, 50, 3604-3617.

23. Anil Kumar, Epoxidation of alkenes with hydrogen peroxide catalyzed by 1-methyl-3-butylimidazolium decatungstate in ionic liquid, Catal. Commun. 2007, 8, 913-916.

22. Anil Kumar, N Jain, SMS Chauhan, Biomimetic oxidation of veratryl alcohol with H2O2 catalyzed by iron(III) porphyrins and HRP in ionic liquid, Synlett 2007, 411-414.

2006

21. X Gu, Y Wang, Anil Kumar, X Lin, G Ye, G Sun, K Parang, Design and evaluation of hydroxamate derivatives as metal-mediated inhibitors of a protein tyrosine kinase, J. Med. Chem. 2006, 49, 7532-7539

20. Anil Kumar, G Ye, Y Ahmadibeni, K Parang, Synthesis of polymer-bound 4-acetoxy-3-phenylbenzaldehyde derivatives: Applications in solid-phase organic synthesis, J. Org. Chem. 2006, 71, 7915-7918

19. Anil Kumar, G Ye, Y Wang, X Lin, G Sun, K Parang, Synthesis and structure-activity relationships of linear and conformationally constrained peptide analogs of CIYKYY as Src tyrosine kinase inhibitors, J. Med. Chem. 2006, 49, 3395-3401.

18. Anil Kumar, SMS Chauhan, Reduction of carbonyl compounds with sodium borohydride in the presence of clays in aprotic solvents, Indian J. Chem. 2006, 45B, 1038-1041. 

2005-2002

17. MK Ayrapetov, NH Nam, G Ye, Anil Kumar, K Parang, Sun G. Functional diversity of Csk, Chk, and Src SH2 domains due to a single residue variation, J. Biol. Chem. 2005, 280, 25780-25787.

16. C Angrish, Anil Kumar, SMS Chauhan, Microwave-assisted aromatic nucleophilic substitution reaction of chloronitrobenzenes with amines in ionic liquids, Indian J. Chem. 2005, 44B, 1515-1518.

15. N Jain, Anil Kumar, SMS Chauhan, Synthesis of transition metal porphyrins from free-base 5,10,15,20-tetraarylporphyrins under microwave irradiation in ionic liquids, Synth. Commun. 2005, 35, 1223-1230.

14. N Jain, Anil Kumar, SMS Chauhan, Metalloporphyrin and heteropoly acid catalyzed oxidation of C=NOH bonds in ionic liquids: Biomimetic models of Nitric Oxide Synthase, Tetrahedron Lett. 2005, 46, 2599-2602.

13. N Jain, Anil Kumar, S Chauhan, SMS Chauhan, Chemical and biochemical transformations in ionic liquids, Tetrahedron 2005, 61, 1015-1060,

12. BS Chhikara, S Tehlan, Anil Kumar, 1-Methyl-3-butylimidazolium decatungstate in ionic liquid: An efficient catalyst for the oxidation of alcohols, Synlett 2005, 63-66.

11. Anil Kumar, N Jain, S Rana, SMS Chauhan, Ytterbium(III) triflate in ionic liquids: An efficient catalyst for conversion of carbonyl compounds into 1,3-oxathiolanes, Synlett 2004, 2785-2787.

10. Anil Kumar, N Jain, SMS Chauhan, Oxidation of benzylic alcohols to carbonyl compounds with potassium permanganate in ionic liquids, Synth. Commun. 2004, 34, 2835-2842.

9. SMS Chauhan, Anil Kumar, KA Srinivas, β-polynitration of 5,10,15,20-tetra(2,6'-dichlorophenyl)porphyrins using HNO3 and Cu(NO2)3 on clays under microwave irradiation, Synth. Commun. 2004, 34, 2673-2680.

8.  SMS Chauhan, M Singh, Anil Kumar, Isolation and characterization of selected secondary metabolites from dry leaves of Quercus Semicarpifolia, Indian J. Chem. 2004, 43B, 223-226.

7.  SMS Chauhan, Anil Kumar, KA Srinivas, MK Mishra, Effect of chain length on the aggregation of 5,10,15-tris(1-methylpyridinium-4yl)-20-[4-(alkoxy)phenyl]-21H, 23H-poprhyrin tritosylates, Indian J. Biochem. Biophy. 2003, 40, 429-438.

6.  SMS Chauhan, Anil Kumar, KA Srinivas, Oxidation of thiols with molecular oxygen catalyzed by cobalt(II) phthalocyanines in ionic liquids, Chem. Commun. 2003, 2348-2349.

5.  SMS Chauhan, KA Srinivas, N Jain, Anil Kumar, Biomimetic oxidation of curcumin with hydrogen peroxide catalyzed by 5,10,15,20-tetraarylporphyrinato(III) chlorides in dichloromethane, Chem. Pharm. Bull. 2003, 51, 1345-1347.

4.  SMS Chauhan, N Jain, Anil Kumar, KA Srinivas, Copper(I) catalyzed synthesis of diarylethers in ionic liquids under mild conditions, Synth. Commun. 2003, 33, 3607-3614.

3.  SMS Chauhan, Anil Kumar, BB Sahoo, Deprotection of 1,3-oxathiolanes to carbonyl compounds with montmorillinite K10, Indian J. Chem. 2003, 42B, 2635-2637.

2.   KA Srinivas, Anil Kumar, SMS Chuahan, Epoxidation of alkenes with hydrogen peroxide catalyzed by iron(III) porphyrins in ionic liquids, Chem. Commun. 2002, 2456-2457.

1. SMS Chauhan, KA Srinivas, Anil Kumar, Biomimetic reduction of nimesulide with NaBH4 catalyzed by metalloporphyrins, Chem. Pharm. Bull. 2002, 50, 1421-1422.

 

 

 

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